Hla complex group 22

HCG22
Identifiers
Aliases	HCG22 , PBMUCL2, HLA complex group 22, HLA complex group 22 (gene/pseudogene)
External IDs	GeneCards: HCG22
Gene location (Human)
Chr.	Chromosome 6 (human) [1]
End	31,059,890 bp [1]
Orthologs
	285834
	n/a
ENSG00000228147 ; ENSG00000225629 ; ENSG00000237894 ; ENSG00000238234 ; ENSG00000228789 ;
	ENSG00000227974 ; ENSG00000237093 ; ENSG00000229501
	n/a
	E2RYF7
	n/a
	NM_001348249
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

Last updated April 07, 2019

HLA complex group 22 is a protein that in humans is encoded by the HCG22 gene. ^[3]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

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HLA-E protein-coding gene in the species Homo sapiens

HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E gene. The human HLA-E is a non-classical MHC class I molecule that is characterized by a limited polymorphism and a lower cell surface expression than its classical paralogues. The functional homolog in mice is called Qa-1b, officially known as H2-T23.

HLA-DQB1 protein-coding gene in the species Homo sapiens

Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.

Transporter associated with Antigen Processing 1 is a protein that in humans is encoded by the TAP1 gene.

Major histocompatibility complex, class II, DQ alpha 1 protein-coding gene in the species Homo sapiens

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HLA class II histocompatibility antigen, DM beta chain is a protein that in humans is encoded by the HLA-DMB gene.

HLA class II histocompatibility antigen, DM alpha chain is a protein that in humans is encoded by the HLA-DMA gene.

Killer cell immunoglobulin-like receptor 2DL1 is a protein that in humans is encoded by the KIR2DL1 gene.

HLA class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene.

HLA class II histocompatibility antigen, DO beta chain is a protein that in humans is encoded by the HLA-DOB gene.

Killer cell immunoglobulin-like receptor 3DL2 is a protein that in humans is encoded by the KIR3DL2 gene.

HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23.2, it is part of the human leucocyte antigen system.

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Serine/threonine-protein kinase 19 is an enzyme that in humans is encoded by the STK19 gene.

TAP2 is a gene in humans that encodes the protein Antigen peptide transporter 2.

Protein BAT4 is a protein that in humans is encoded by the BAT4 gene.

Complement component 4B is a protein that in humans is encoded by the C4B gene.

Hla complex group 22

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References

Further reading