Holliday-Segar formula

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The Holliday-Segar formula is a formula to help approximate water and caloric loss (and therefore the water requirements) using a patient's body weight. [1] Primarily aimed at pediatric patients, the Holliday-Segar formula is the most commonly used estimate of daily caloric requirements. [2] To date, the formula continues to be recommended in the current clinical practice guidelines of the American Academy of Pediatrics, American Society of Parenteral and Enteral Nutrition, and National Health Service. [3] [4] [5] Developed in 1957 by Drs. Malcolm A. Holliday and William E. Segar while at the Indiana University School of Medicine, the researchers concluded a non-linear relationship between energy expenditure and weight alone to determine fluid requirements.

Contents

The Holliday-Segar Formula
For each kilogram in this rangeDaily caloric cost per kilogram
1–10 kg100 kcal/kg/day
11–20 kg50 kcal/kg/day
>20 kg20 kcal/kg/day

Worked example

To estimate the daily fluid requirements of a 9-year-old boy who weights 32 kg, 10*100 + 10*50 + 12*20 = 1740 kcal per day. At a 1 kcal / 1 mL conversion, the daily H20 requirements would therefore be 1740 mL.

Limitations

While generalizable to most cohorts, the Holliday-Segar formula may inadequately estimate caloric requirements in patients affected by fever, hypothermia, or increased activity states (i.e., hyperthyroidism or status epilepticus). [2] The formula can also only be applied to patients above 2 weeks of age.

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References

  1. Holliday, M. A.; Segar, W. E. (1957). "The maintenance need for water in parenteral fluid therapy". Pediatrics. 19 (5): 823–832. doi:10.1542/peds.19.5.823. ISSN   0031-4005. PMID   13431307.
  2. 1 2 "Dehydration in Children - Pediatrics". Merck Manuals Professional Edition. Retrieved 2021-01-12.
  3. Feld, Leonard G.; Neuspiel, Daniel R.; Foster, Byron A.; Leu, Michael G.; Garber, Matthew D.; Austin, Kelly; Basu, Rajit K.; Conway, Edward E.; Fehr, James J.; Hawkins, Clare; Kaplan, Ron L. (2018). "Clinical Practice Guideline: Maintenance Intravenous Fluids in Children". Pediatrics. 142 (6): e20183083. doi: 10.1542/peds.2018-3083 . ISSN   0031-4005. PMID   30478247. S2CID   53743151.
  4. Mehta, Nilesh M.; Skillman, Heather E.; Irving, Sharon Y.; Coss-Bu, Jorge A.; Vermilyea, Sarah; Farrington, Elizabeth Anne; McKeever, Liam; Hall, Amber M.; Goday, Praveen S.; Braunschweig, Carol (2017). "Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Pediatric Critically Ill Patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition". Journal of Parenteral and Enteral Nutrition. 41 (5): 706–742. doi: 10.1177/0148607117711387 . ISSN   0148-6071. PMID   28686844.
  5. Moritz, Michael L.; Ayus, Juan C. (2015-09-30). "Maintenance Intravenous Fluids in Acutely Ill Patients". New England Journal of Medicine. 373 (14): 1350–1360. doi:10.1056/nejmra1412877. PMID   26422725 . Retrieved 2021-01-12.