Imidacloprid/permethrin/pyriproxyfen

Imidacloprid/permethrin/pyriproxyfen
Combination of
Imidacloprid	Insecticide
Permethrin	Pyrethroid insecticide
Pyriproxyfen	Insecticide
Clinical data
Trade names	K9 Advantix II

Last updated January 31, 2026

Imidacloprid/permethrin/pyriproxyfen, sold under the trade name K9 Advantix II, is a combination insecticide product for dogs, used for the treatment and prevention of an array of common external parasites. It is effective against fleas, ticks, chewing lice and mosquitoes.^[1] The active ingredients are imidacloprid, permethrin, and pyriproxyfen. This product is toxic to cats,^[2] and it is not recommended for use on dogs which share an environment with cats.^[1] The product is applied onto the skin; administration of the product into the mouth can cause adverse effects.^[3]

References

1 2 Koch SN, Torres SM, Plumb DC (1 May 2012). Canine and Feline Dermatology Drug Handbook. John Wiley & Sons. pp. 336–337. ISBN 978-1-4051-9896-7.
↑ Bill RL (2017). "Current (2016) flea and tick products used in small animals (major U.S. brands)". Clinical Pharmacology and Therapeutics for Veterinary Technicians (4th ed.). St Louis, Missouri: Elsevier Inc. p. 278. ISBN 978-0-323-08679-0.
↑ Wanamaker BP, Massey KL (2015). "Imidacloprid, Imidacloprid with Permethrin, and Imidaclopride with Moxidectin". Applied pharmacology for veterinary technicians (5th ed.). St Louis, Missouri: Elsevier Inc. p. 226. ISBN 978-0-323-18662-9.

This veterinary medicine –related article is a stub. You can help Wikipedia by adding missing information.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[KochTorres2012-1] 1 2 Koch SN, Torres SM, Plumb DC (1 May 2012). Canine and Feline Dermatology Drug Handbook. John Wiley & Sons. pp. 336–337. ISBN 978-1-4051-9896-7.

[2] Bill RL (2017). "Current (2016) flea and tick products used in small animals (major U.S. brands)". Clinical Pharmacology and Therapeutics for Veterinary Technicians (4th ed.). St Louis, Missouri: Elsevier Inc. p. 278. ISBN 978-0-323-08679-0.

[3] Wanamaker BP, Massey KL (2015). "Imidacloprid, Imidacloprid with Permethrin, and Imidaclopride with Moxidectin". Applied pharmacology for veterinary technicians (5th ed.). St Louis, Missouri: Elsevier Inc. p. 226. ISBN 978-0-323-18662-9.

[1]

[2]

[3]