International Molecular Exchange Consortium

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International Molecular Exchange Consortium

The International Molecular Exchange Consortium (IMEx) [1] is a group of the major public providers of molecular interaction data to provide a single, non-redundant set of molecular interactions. Data is captured using a detailed curation model and made available in the PSI-MI standard formats. Participating databases include DIP, IntAct, [2] the Molecular Interaction Database (MINT), [3] MatrixDB, [4] InnateDB, IID, HPIDB, UCL Cardiovascular Gene Annotation, MBInfo, Molecular Connections and UniProt. [1] The group collates the interaction data and prevents duplicate entries in the various databases. The IMEx consortium also supports and contributes to the development of the HUPO-PSI-MI XML format, which is now widely implemented. [1] [5]

External references

IMEx website

References

  1. 1 2 3 Orchard, S.; Kerrien, S.; Abbani, S.; Aranda, B.; Bhate, J.; Bidwell, S.; Bridge, A.; Briganti, L.; Brinkman, F.; Cesareni, G.; Chatr-Aryamontri, A.; Chautard, E.; Chen, C.; Dumousseau, M.; Goll, J.; Hancock, R.; Hannick, L. I.; Jurisica, I.; Khadake, J.; Lynn, D. J.; Mahadevan, U.; Perfetto, L.; Raghunath, A.; Ricard-Blum, S.; Roechert, B.; Salwinski, L.; Stümpflen, V.; Tyers, M.; Uetz, P.; Xenarios, I. (2012). "Protein interaction data curation: The International Molecular Exchange (IMEx) consortium". Nature Methods. 9 (4): 345–350. doi:10.1038/nmeth.1931. PMC   3703241 . PMID   22453911.
  2. ↑ Kerrien, S.; Aranda, B.; Breuza, L.; Bridge, A.; Broackes-Carter, F.; Chen, C.; Duesbury, M.; Dumousseau, M.; Feuermann, M.; Hinz, U.; Jandrasits, C.; Jimenez, R. C.; Khadake, J.; Mahadevan, U.; Masson, P.; Pedruzzi, I.; Pfeiffenberger, E.; Porras, P.; Raghunath, A.; Roechert, B.; Orchard, S.; Hermjakob, H. (24 November 2011). "The IntAct molecular interaction database in 2012". Nucleic Acids Research. 40 (D1): D841 –D846. doi:10.1093/nar/gkr1088. PMC   3245075 . PMID   22121220.
  3. ↑ Zanzoni, A; Montecchi-Palazzi, L; Quondam, M; Ausiello, G; Helmer-Citterich, M; Cesareni, G (Feb 20, 2002). "MINT: a Molecular INTeraction database". FEBS Letters. 513 (1): 135–40. Bibcode:2002FEBSL.513..135Z. doi:10.1016/s0014-5793(01)03293-8. PMC   1751541 . PMID   11911893.
  4. ↑ Launay, G. (1 January 2014). "MatrixDB, the extracellular matrix interaction database: updated content, a new navigator and expanded functionalities". Nucleic Acids Research. 43 (Database issue): D321 –D327. doi:10.1093/nar/gku1091. PMC   4383919 . PMID   25378329.
  5. ↑ Hermjakob, Henning; Montecchi-Palazzi, Luisa; Bader, Gary; Wojcik, Jérôme; Salwinski, Lukasz; Ceol, Arnaud; Moore, Susan; Orchard, Sandra; Sarkans, Ugis; von Mering, Christian; Roechert, Bernd; Poux, Sylvain; Jung, Eva; Mersch, Henning; Kersey, Paul; Lappe, Michael; Li, Yixue; Zeng, Rong; Rana, Debashis; Nikolski, Macha; Husi, Holger; Brun, Christine; Shanker, K; Grant, Seth G N; Sander, Chris; Bork, Peer; Zhu, Weimin; Pandey, Akhilesh; Brazma, Alvis; Jacq, Bernard; Vidal, Marc; Sherman, David; Legrain, Pierre; Cesareni, Gianni; Xenarios, Ioannis; Eisenberg, David; Steipe, Boris; Hogue, Chris; Apweiler, Rolf (2004). "The HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data". Nature Biotechnology. 22 (2): 177–183. doi:10.1038/nbt926. PMID   14755292. S2CID   17557764.
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