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The Israel Cancer Research Fund (ICRF) a cancer research fund founded in 1975 by a group of American and Canadian physicians, scientists, and laypeople. The ICRF was founded to prevent the permanent loss of Israel's cancer researchers to foreign universities due to the lack of funding in Israel for newly minted Ph. D.s, post-doctoral fellows and accomplished young scientists (a phenomenon known to many as Israel's "brain drain"). With chapters in New York, Los Angeles, Chicago, Toronto, Montreal, and Jerusalem, ICRF annually sponsors a grant review process conducted by an expert panel of U.S. and Canadian scientists and oncologists and modeled on the NIH grant-making process.
Awards are granted directly to Israeli cancer researchers at all the leading academic and biomedical research centers throughout Israel[ citation needed ]. To date, the ICRF has funded more than $87 million in awards to Israeli cancer researchers via more than 2,700 fellowships, project grants, career development awards, and professorships. [1] Grants have been provided to over 20 institutions including all major hospitals, universities, and cancer research projects throughout Israel. Breakthrough discoveries by ICRF-funded scientists have led to the development of Gleevec -used in the successful treatment of chronic myelogenous leukemia[ citation needed ]; Doxil - used in the treatment of breast & ovarian cancer as well as AIDS[ citation needed ]; p53 – a key tumor suppressor; RAD 51 which identifies the likelihood of breast cancer occurring in women who carry the BRCA 2 gene and Velcade[ citation needed ]. The basic research ICRF funds have led to treatments and drugs that are benefiting cancer patients around the world.
The National Institutes of Health, commonly referred to as NIH, is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program.
Cancer Research UK (CRUK) is the world's largest independent cancer research organisation. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and the Imperial Cancer Research Fund. Cancer Research UK conducts research using both its own staff and grant-funded researchers. It also provides information about cancer and runs campaigns aimed at raising awareness and influencing public policy.
Scripps Research, previously known as The Scripps Research Institute (TSRI), is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California, the institute has over 170 laboratories employing 2,100 scientists, technicians, graduate students, and administrative and other staff.
The University of Texas MD Anderson Cancer Center is a comprehensive cancer center in Houston, Texas. It is the largest cancer center in the world and one of the original three NCI-designated comprehensive cancer centers in the country. It is both a degree-granting academic institution and a cancer treatment and research center located within Texas Medical Center (TMC), Houston, the largest medical center and life sciences destination in the world. MD Anderson Cancer Center has consistently ranked #1 among the best hospitals for cancer care and research in the U.S. and worldwide, and it has held the #1 position 19 times in the last 22 years on U.S. News & World Report's Best Hospitals rankings for cancer care. As of 2023, MD Anderson Cancer Center is home to the highest number of cancer clinical trials in the world and has received more NCI-funded projects than any other U.S. institute. In 2024, Newsweek placed MD Anderson at #1 in their annual list of the World's Best Specialized Hospitals in oncology.
Research funding is a term generally covering any funding for scientific research, in the areas of natural science, technology, and social science. Different methods can be used to disburse funding, but the term often connotes funding obtained through a competitive process, in which potential research projects are evaluated and only the most promising receive funding. It is often measured via Gross domestic expenditure on R&D (GERD).
Medical research, also known as health research, refers to the process of using scientific methods with the aim to produce knowledge about human diseases, the prevention and treatment of illness, and the promotion of health.
The Canadian Cancer Society is Canada's largest national cancer charity and the largest national charitable funder of cancer research in Canada.
Susan G. Komen is a breast cancer organization in the United States.
The Jackson Laboratory is an independent, non-profit biomedical research institution which was founded by Clarence Cook Little in 1929. It employs over 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, Connecticut; Shanghai, China; and Yokohama, Japan. The institution is a National Cancer Institute-designated Cancer Center and has NIH Centers of Excellence in aging and systems genetics. The stated mission of The Jackson Laboratory is "to discover the genetic basis for preventing, treating and curing human diseases, and to enable research and education for the global biomedical community."
The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research. Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and translational research into the etiology, prevention, diagnosis, and treatment of cancer. Founded in 1907 by 11 physicians and scientists, the organization now has more than 58,000 members in 142 countries and territories. The mission of the AACR is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research.
A biomedical scientist is a scientist trained in biology, particularly in the context of medical laboratory sciences or laboratory medicine. These scientists work to gain knowledge on the main principles of how the human body works and to find new ways to cure or treat disease by developing advanced diagnostic tools or new therapeutic strategies. The research of biomedical scientists is referred to as biomedical research.
Europe PubMed Central is an open-access repository that contains millions of biomedical research works. It was known as UK PubMed Central until 1 November 2012.
Martine J. Piccart-Gebhart is a Belgian medical oncologist. She is a professor of oncology at the Université Libre de Bruxelles and scientific director at the Jules Bordet Institute in Brussels, Belgium. She is also a member of the Belgian Royal Academy of Medicine.
The Breast Cancer Research Foundation (BCRF) is an independent, not-for-profit organization which has raised $569.4 million to support clinical and translational research on breast cancer at medical institutions in the United States and abroad. BCRF currently funds over 255 researchers in 14 countries.
The Prostate Cancer Foundation (PCF), headquartered in Santa Monica, California, funds research into the prevention and cure of prostate cancer.
Biomedical sciences are a set of sciences applying portions of natural science or formal science, or both, to develop knowledge, interventions, or technology that are of use in healthcare or public health. Such disciplines as medical microbiology, clinical virology, clinical epidemiology, genetic epidemiology, and biomedical engineering are medical sciences. In explaining physiological mechanisms operating in pathological processes, however, pathophysiology can be regarded as basic science.
The PA Research Foundation (PARF) is an Australian Non for Profit Organization that raises funds for lifesaving research to develop better diagnoses and treatments for some of Australia’s biggest health challenges.
The Edinburgh Cancer Research Centre (ECRC), also known as the University of Edinburgh Cancer Research Centre, is a center for basic, translational and clinical cancer research located in Edinburgh, Scotland. ECRC constitutes a part of the Institute of Genetics & Molecular Medicine (IGMM) and is positioned in direct proximity of the Western General Hospital, where most of its clinical activities take place.
The Cancer Research Institute (CRI) is a US non-profit organization funding cancer research and based in New York City. They were founded in 1953 to develop immunologically-based treatments for cancer, and despite their name are a funding body for research rather than a research institute themselves, working with other institutes and organizations. It was founded by Helen Coley Nauts and Oliver R. Grace with a $2,000 grant from Nelson Rockefeller. CRI was created in honor of Nauts' father, William Coley (1862–1936), an American orthopedic surgeon and a pioneer of cancer immunotherapy. Grounded in Dr. Coley’s pioneering work, the Cancer Research Institute focuses on immunological treatments for cancer, both as a single treatment approach as well as a complement and enhancer to traditional treatments, such as chemotherapy and surgery.
A physician-scientist or clinician-scientist is a physician who divides their professional time between direct clinical practice with patients and scientific research. Physician-scientists traditionally hold both a medical degree and a doctor of philosophy, also known as an MD-PhD. Compared to other clinicians, physician-scientists invest significant time and professional effort in scientific research, with ratios of research to clinical time ranging from 50/50 to 80/20.