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Jackson Thomas "Steve" Stephens Jr (born July 24, 1952) is an American businessman and the founder, chairman, and CEO of Exoxemis, Inc., a biomedical research company. [1] He is the former chairman of The Club for Growth and the chairman of The Club for Growth Foundation. Stephens also co-founded the Arkansas Policy Foundation. Stephens has recorded in Nashville studios and released several albums on which he wrote most of the music and lyrics while playing all the keyboards.
Stephens was born on July 24, 1952, and received a bachelor's degree in business and economics from Hendrix College in Conway, Arkansas. [2]
From 1973 to 1983, Stephens worked in all aspects of his family's firm, Stephens Inc., in Little Rock. At that time, it was an investment/merchant bank, which took Walmart, J.B. Hunt, and others public while making investments for its own account. During his 10 years at Stephens, the firm became the largest investment bank off Wall Street in terms of capital and remained so until 1985. [3] [4]
In 1987, Stephens began a quest to explore and understand the role of oxygen in biological systems for use in diagnostics and therapeutics. To help direct that effort, Stephens hired Robert C. Allen. [5] Allen had discovered cellular chemiluminescence. Allen's understanding of the quantum mechanics of the neutrophil, white blood cells, and the human immune system was the key to his invention of a chemiluminescence diagnostic system that provides comprehensive, point-of-care analysis of a patient's illness-disease profile. In developing this diagnostic system, Allen also discovered the role that myeloperoxidase plays in the human immune system and its natural ability to selectively bind and kill pathogens. Allen previously worked as a pathologist for Basil Pruitt, [6] surgeon, known as one of the founding fathers of modern trauma and burn medicine.
Stephens founded Exoxemis in 1987 and since that time has collaborated with Allen on the development and commercialization of Zempia, [7] the company's trade name for the first, topical antiseptic that works safely in blood. Stephens and Allen have co-authored a number of peer-reviewed journal articles on the microbicidal activity of myeloperoxidase (MPO), the active pharmaceutical ingredient in Zempia.[ citation needed ] In 2010, the American Society for Microbiology (ASM) published a paper in The Journal of Infection and Immunity titled “Myeloperoxidase Selectively Binds and Selectively Kills Microbes.” [8] An initial patent (priority date February 1991) was issued on the Zempia technology in 1999.[ citation needed ]
Stephens joined The Club for Growth board in 2003. Stephens was chairman of the club from 2010 to 2019.[ citation needed ] Stephens helped expand the club's focus from Republican House primaries into U.S. Senate races. In the 2004 Senate race, Pat Toomey challenged Senator Arlen Specter (Pennsylvania) who was supported by President George W. Bush and his cabinet and a cadre of professional politicians including Bush's senior adviser and deputy chief of staff, Karl Rove. Stephens was Toomey's principal supporter. Although Toomey lost the primary by less than 2 percent, the campaign effectively launched the Club into the center of key Senate races and established the club as a significant force in American politics. Toomey became the club's president, and in 2010 was elected senator (Pennsylvania).
Stephens was elected chairman of the club's Foundation in 2019.
Stephens cofounded the Arkansas Policy Foundation in 1995. [9] In 1996, Stephens helped recruit Madison Murphy who led the Murphy Commission (1996–1999). [10] [11]
Stephens chaired the Murphy Commission's statewide education work group. In 2001, Stephens helped establish the first open-enrollment public charter school in Arkansas: Academics Plus Charter Schools, Inc. Stephens later served on its board. [12]
Stephens began playing an electric piano with his boyhood friend Jimmy Roberts in 1964. The duo formed a band and after several name changes decided on Rayburn. They played clubs, opened for Three Dog Night, and acted as Chuck Berry’s backing band when he played in town. In 1974, Jimmy Roberts died of spinal cancer, and Stephens put his musical interests aside. In 2009, Jimmy Roberts’ older brother suggested a reunion of living band members. Since 2010, Rayburn has released two albums, one of which was nominated in three Grammy categories. [13]
Phagocytosis is the process by which a cell uses its plasma membrane to engulf a large particle, giving rise to an internal compartment called the phagosome. It is one type of endocytosis. A cell that performs phagocytosis is called a phagocyte.
The Council on Foreign Relations (CFR) is an American think tank specializing in U.S. foreign policy and international relations. Founded in 1921, it is an independent and nonpartisan nonprofit organization. CFR is based in New York City, with an additional office in Washington, D.C. Its membership has included senior politicians, numerous secretaries of state, CIA directors, bankers, lawyers, professors, corporate directors and CEOs, and senior media figures.
The University of Arkansas is a public land-grant research university in Fayetteville, Arkansas. It is the flagship campus of the University of Arkansas System. Founded as Arkansas Industrial University in 1871, classes were first held in 1872, with its present name adopted in 1899.
Hendrix College is a private liberal arts college in Conway, Arkansas. Approximately 1,000 students are enrolled, mostly undergraduates. While affiliated with the United Methodist Church, the college offers a secular curriculum and has a student body composed of people from many different religious backgrounds. Hendrix is a member of the Associated Colleges of the South.
Nathaniel Charles Jacob Rothschild, 4th Baron Rothschild,, was a British peer, investment banker and member of the Rothschild banking family. Rothschild held important roles in business and British public life, and was active in charitable and philanthropic areas.
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection, against other foreign proteins, or to one's own proteins. In either case, the procedure is simple.
The Star-Club was a music club in Hamburg, Germany, that opened on Friday 13 April 1962, and was initially operated by Manfred Weissleder and Horst Fascher. In the 1960s, many of the giants of rock music played at the club. The club closed on 31 December 1969 and the building it occupied was destroyed by a fire in 1987. The address of the club was Große Freiheit 39 in the St. Pauli quarter of Hamburg. Große Freiheit is a side street of the Reeperbahn. The club had a capacity of 2,000 people, and cinema-style seating.
Blue Wild Angel: Live at the Isle of Wight is a posthumous live album by Jimi Hendrix released on November 12, 2002. The album documents Hendrix's last U.K. live performance at the Isle of Wight Festival on August 31, 1970, three weeks before his death. The set list for the concert contained songs from the original Experience albums, as well as new songs. Some were previously available on Isle of Wight (1971) and Live Isle of Wight '70 (1991). "Power to Love ", "Midnight Lightning", and "Foxy Lady" released in the US on the three record set The First Great Rock Festivals of the 70s: Isle of Wight/Atlanta Pop Festival" released on Columbia Records in 1971.
Allen Strange was an American composer. He authored two books, Electronic Music: Systems, Techniques, and Controls and Programming and Meta-Programming the Electro-Organism. He co-wrote The Contemporary Violin: Extended Performance Techniques with his wife, Patricia.
"Killing Floor" is a 1964 song by American blues singer-songwriter and guitarist Howlin' Wolf. Called "one of the defining classics of Chicago electric blues", "Killing Floor" became a blues standard with recordings by various artists. It has been acknowledged by the Blues Foundation Hall of Fame, which noted its popularity among rock as well as blues musicians. English rock group Led Zeppelin adapted the song for their "The Lemon Song", for which Howlin' Wolf is named as a co-author.
Stephen Mark "Steve" Saleen is an American businessman and former racing driver. He is best known for being the founder and former vice chairman of Saleen, Inc., originally named Saleen Autosport, which is an OEM manufacturer of specialty vehicles including the Saleen S1, Saleen S7 and highly modified Ford Mustangs.
Allen Bernard West is an American politician and retired military officer. A member of the Republican Party, West represented Florida's 22nd congressional district in the United States House of Representatives from 2011 to 2013 and served as the chairman of the Republican Party of Texas from 2020 to 2021.
John Walter Hendrix is a retired United States Army four-star general who served as Commander, United States Army Forces Command from 1999 to 2001.
CHI-California Healthcare Institute is a private, non-profit public policy research and advocacy organization, representing more than 250 universities, academic research centers, biotechnology, and medical device companies. Founded in 1993, and based in La Jolla, California, CHI has offices in Washington, D.C., and Sacramento, California. CHI publishes an annual California Biomedical Industry report, providing data on the scope and scale of academic and commercial life sciences research and development within the state. In 2008, the industry employed more than 270,000 Californians and produced revenues in excess of $75 billion.
Claiborne P. Deming is an American attorney, business executive and philanthropist. He served as the president and chief executive officer of Murphy Oil from 1994 to 2008. Since 2008, he has served as its chairman. Additionally, he serves as senior advisor to TPH Partners, an energy private equity firm. As a philanthropist, he has supported public schools in Arkansas and private universities in the Southern United States.
The units of the Arkansas Militia in the Civil War to which the current Arkansas National Guard has a connection include the Arkansas State Militia, Home Guard, and State Troop regiments raised by the State of Arkansas. Like most of the United States, Arkansas had an organized militia system before the American Civil War. State law required military service of most male inhabitants of a certain age. Following the War with Mexico, the Arkansas militia experienced a decline, but as sectional frictions between the north and south began to build in the late 1850s the militia experienced a revival. By 1860 the state's militia consisted of 62 regiments divided into eight brigades, which comprised an eastern division and a western division. New regiments were added as the militia organization developed. Additionally, many counties and cities raised uniformed volunteer companies, which drilled more often and were better equipped than the un-uniformed militia. These volunteer companies were instrumental in the seizure of federal installations at Little Rock and Fort Smith, beginning in February 1861.
Mayo v. Prometheus, 566 U.S. 66 (2012), was a case decided by the Supreme Court of the United States that unanimously held that claims directed to a method of giving a drug to a patient, measuring metabolites of that drug, and with a known threshold for efficacy in mind, deciding whether to increase or decrease the dosage of the drug, were not patent-eligible subject matter.
The Business Council is an organization of business leaders headquartered in Washington, D.C. It holds meetings several times a year for high-level policy discussions.
Jo Lynn "Jody" Allen is an American businesswoman, entrepreneur, and philanthropist. She is the sister of Microsoft co-founder Paul Allen, and served as the chief executive officer of his investment and project management company, Vulcan Inc., from its founding in 1986 until 2015. She is also the co-founder and president of the Paul G. Allen Family Foundation.
Eosinophil peroxidase is an enzyme found within the eosinophil granulocytes, innate immune cells of humans and mammals. This oxidoreductase protein is encoded by the gene EPX, expressed within these myeloid cells. EPO shares many similarities with its orthologous peroxidases, myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). The protein is concentrated in secretory granules within eosinophils. Eosinophil peroxidase is a heme peroxidase, its activities including the oxidation of halide ions to bacteriocidal reactive oxygen species, the cationic disruption of bacterial cell walls, and the post-translational modification of protein amino acid residues.