Jeffrey J. Wine is an American biologist and professor. He is currently at Stanford University and an Elected Fellow of the American Association for the Advancement of Science. [1] [2] [3] His research has focused on the genetic disease cystic fibrosis. [4] [5]
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms.
Jennifer Ann Agutter is a British actress. She began her career as a child actress in 1964, appearing in East of Sudan, Star!, and two adaptations of The Railway Children—the BBC's 1968 television serial and the 1970 film version. She also starred in the critically acclaimed film Walkabout and the TV film The Snow Goose, for which she won an Emmy Award for Outstanding Supporting Actress in a Drama.
Bob Flanagan was an American performance artist and writer known for his work on sadomasochism and lifelong struggle with cystic fibrosis.
Lap-Chee Tsui is a Chinese-born Canadian geneticist and served as the 14th Vice-Chancellor and President of the University of Hong Kong.
Donald Kennedy was an American scientist, public administrator, and academic. He served as Commissioner of the U.S. Food and Drug Administration (1977–1979), President of Stanford University (1980–1992), and Editor-in-Chief of Science (2000–2008). Following this, he was named president emeritus of Stanford University; Bing Professor of Environmental Science and Policy, emeritus; and senior fellow of the Freeman Spogli Institute for International Studies.
The Carleton University Students' Association is a non-profit corporation that represents the undergraduate students at Carleton University in Ottawa, Ontario, Canada.
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.
Vertex Pharmaceuticals is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in South Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, near Oxford, England.
David Bourne, known professionally as JR Bourne, is a Canadian actor. He portrayed Chris Argent on all six seasons of the MTV supernatural drama series Teen Wolf (2011–2017) and was part of the main cast in the final season. Bourne has also appeared as a series regular on the ABC mystery drama Somewhere Between (2017) and The CW science fiction drama The 100 (2019–2020). Other notable television roles include Martouf / Lantash on the Showtime science fiction adventure Stargate SG-1 (1998–2000), CIA Agent Edwards on the Fox science fiction drama Fringe (2009–2011), and Kenny Ryan on the ABC drama Revenge (2012–2013).
Dorothy Hansine Andersen was an American physician, pediatrician, and pathologist who was the first person to identify cystic fibrosis, the first to describe the disease, and the one to name it. in 1939, she was awarded the E. Mead Johnson Award for her identification of the disease. In 2002, she was inducted into the National Women's Hall of Fame.
The Cystic Fibrosis Foundation (CFF) is a 501(c)(3) non-profit organization in the United States established to provide the means to cure cystic fibrosis (CF) and ensure that those living with CF live long and productive lives. The Foundation provides information about cystic fibrosis and finances CF research that aims to improve the quality of life for people with the disease. The Foundation also engages in legislative lobbying for cystic fibrosis.
Maynard Victor Olson is an American chemist and molecular biologist. As a professor of genome sciences and medicine at the University of Washington, be became a specialist in the genetics of cystic fibrosis, and one of the founders of the Human Genome Project. During his years at Washington University in St. Louis, he also led efforts to develop yeast artificial chromosomes that allowed for the study of large portions of the human genome.
Charlotte Morrison Anderson AM FRACP FRCP FACP FRCPCH was an internationally renowned Australian scientist, physician and academic. She pioneered the field of paediatric gastroenterology working on health issues including cystic fibrosis and coeliac disease. She was the first woman professor of paediatrics in the United Kingdom.
Davis Richard Cleveland is an American child actor. He is known for his role as Flynn Jones on the Disney Channel original series Shake It Up. Cleveland starred as Manny in the 2016 Nickelodeon Original Movie Rufus and its 2017 sequel Rufus 2.
Ivacaftor is a medication used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis. It is also included in combination medications, lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis.
Jeffrey Leiden, M.D., Ph.D. is the executive chairman of Vertex Pharmaceuticals, a biotechnology company based in Boston, Massachusetts. He was initially appointed to the board of directors of the company in 2009 and was CEO and president from February 2012 to March 2020.
Five Feet Apart is a 2019 American romantic drama film directed by Justin Baldoni and written by Mikki Daughtry and Tobias Iaconis. The film was inspired by Claire Wineland, who suffered from cystic fibrosis. Haley Lu Richardson and Cole Sprouse play two young patients with cystic fibrosis who try to have a relationship despite being forced to stay six feet apart from each other. The film was released in the United States on March 15, 2019 by CBS Films via Lionsgate. It received mixed reviews from critics and has grossed over $91 million worldwide.
Phyllis I. Gardner is a Professor of Medicine at the Stanford University School of Medicine. She has previously served as Dean of Education. Gardner was one of the first people to be publicly skeptical of Elizabeth Holmes, the founder of blood testing company Theranos, who was later found guilty of investor fraud.
Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta (US) and Kaftrio (EU), is a fixed-dose combination medication used to treat cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor is composed of a combination of ivacaftor, a chloride channel opener, and elexacaftor and tezacaftor, CFTR modulators.
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