Jo Douglass

Last updated
Jo A. Douglass
NationalityAustralia
EducationMonash University
OccupationHealth researcher
EmployerRoyal Melbourne Hospital
Known forAsthma and Allergy research
TitleProfessor
Website https://findanexpert.unimelb.edu.au/profile/32737-jo-douglass

Jo A. Douglass or Jo Anne Douglass; (born ) is an Australian asthma researcher, Director of Research within the Royal Melbourne Hospital, James Stewart Professor of Medicine and she is also Department Head of Medicine within the Melbourne Medical School. She was awarded an Order of Australia, [1] for her "distinguished service to medical research, to clinical immunology and allergy, to respiratory medicine, and to tertiary education." [2]

Contents

Education and career

Douglass received her undergraduate degree, in Medical Science, and Bachelor of Medicine and Bachelor of Surgery at Monash University, and subsequently completed postgraduate education in London. [3] She was the president of the Australasian Society of Clinical Immunology and Allergy from 2010 to 2012, [4] as well as a member of the European Respiratory Society. [5]

At the Royal Melbourne Hospital, Douglass was the head of Department of Immunology and Allergy. [6] She specialises in the clinical and research of both asthma and allergic disease, at Royal Melbourne Hospital. [7]

Douglass's research is centered around the clinical and research of asthma and allergies, including thunderstorm asthma, diagnosis using genomic medicine, as well as immune deficiencies. [8]

Publications

Douglass has an H-index of 43, according to Google Scholar, [9] and more than 100 publications as at July 2024. [10] [11] Select examples include:

Awards

Related Research Articles

<span class="mw-page-title-main">Asthma</span> Long-term inflammatory disease of the airways of the lungs

Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise.

<span class="mw-page-title-main">Allergy</span> Immune system response to a substance that most people tolerate well

Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, coughing, a runny nose, shortness of breath, or swelling. Note that food intolerances and food poisoning are separate conditions.

An allergen is an otherwise harmless substance that triggers an allergic reaction in sensitive individuals by stimulating an immune response.

Anaphylaxis is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of the use of emergency medication on site. It typically causes more than one of the following: an itchy rash, throat closing due to swelling that can obstruct or stop breathing; severe tongue swelling that can also interfere with or stop breathing; shortness of breath, vomiting, lightheadedness, loss of consciousness, low blood pressure, and medical shock. These symptoms typically start in minutes to hours and then increase very rapidly to life-threatening levels. Urgent medical treatment is required to prevent serious harm and death, even if the patient has used an epipen or has taken other medications in response, and even if symptoms appear to be improving.

<span class="mw-page-title-main">Eosinophil</span> Variety of white blood cells

Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply.

<span class="mw-page-title-main">Rhinitis</span> Irritation and inflammation of the mucous membrane inside the nose

Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose. Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip.

<span class="mw-page-title-main">Omalizumab</span> Monoclonal antibody medication

Omalizumab, sold under the brand name Xolair among others, is an injectable medication to treat severe persistent allergic forms of asthma, nasal polyps, urticaria (hives), and immunoglobulin E-mediated food allergy.

<span class="mw-page-title-main">Aspirin-exacerbated respiratory disease</span> Chronic inflammatory disease affecting the sinuses and lungs

Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). Compared to aspirin tolerant patients, AERD patients' asthma and nasal polyps are generally more severe. Reduction or loss of the ability to smell is extremely common, occurring in more than 90% of people with the disease. AERD most commonly begins in early- to mid-adulthood and has no known cure. While NSAID intolerance is a defining feature of AERD, avoidance of NSAIDs does not affect the onset, development or perennial nature of the disease.

<span class="mw-page-title-main">Allergen immunotherapy</span> Medical treatment for environmental allergies

Allergen immunotherapy, also known as desensitization or hypo-sensitization, is a medical treatment for environmental allergies and asthma. Immunotherapy involves exposing people to larger and larger amounts of allergens in an attempt to change the immune system's response.

Nambudripad's Allergy Elimination Techniques (NAET) is a form of alternative medicine which proponents claim can treat allergies and related disorders. The techniques were devised by Devi Nambudripad, a California-based chiropractor and acupuncturist, in 1983, drawing on a combination of ideas from applied kinesiology, acupuncture, acupressure, nutritional management, and chiropractic methods.

<span class="mw-page-title-main">Cysteinyl leukotriene receptor 1</span> Protein-coding gene in humans

Cysteinyl leukotriene receptor 1, also termed CYSLTR1, is a receptor for cysteinyl leukotrienes (LT). CYSLTR1, by binding these cysteinyl LTs contributes to mediating various allergic and hypersensitivity reactions in humans as well as models of the reactions in other animals.

<span class="mw-page-title-main">ADAM33</span> Protein-coding gene in the species Homo sapiens

Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene.

<span class="mw-page-title-main">Exhaled nitric oxide</span> Breath test for respiratory inflammation

In medicine, exhaled nitric oxide (eNO) can be measured in a breath test for asthma and other respiratory conditions characterized by airway inflammation. Nitric oxide (NO) is a gaseous molecule produced by certain cell types in an inflammatory response. The fraction of exhaled NO (FENO) is a promising biomarker for the diagnosis, follow-up and as a guide to therapy in adults and children with asthma. The breath test has recently become available in many well-equipped hospitals in developed countries, although its exact role remains unclear.

<span class="mw-page-title-main">Thunderstorm asthma</span> Biometeorological phenomenon

Thunderstorm asthma is the triggering of an asthma attack by environmental conditions directly caused by a local thunderstorm. Due to the acute nature of the onset and wide exposure of local populations to the same triggering conditions, severe epidemic thunderstorm asthma events can put significant and unmanageable stress on public health facilities.

Rosemary Jane Boyton is a British immunologist who is Head of Lung Immunology and Adult Infectious Disease at Imperial College London. She works on the molecular immunology of infectious, allergic and autoimmune inflammation. She holds an honorary consultant position at the Royal Brompton Hospital, where she specialises in lung infection.

Donna Elizabeth Davies is a British biochemist and professor of respiratory cell and molecular biology at the University of Southampton. In 2003, Davies was the co-founder of Synairgen, an interferon-beta drug designed to treat patients with asthma and chronic obstructive pulmonary disease.

<span class="mw-page-title-main">Giorgio Walter Canonica</span> Italian allergist and pulmonologist

Giorgio Walter Canonica is an Italian allergist, pulmonologist and professor of Respiratory Medicine at Humanitas University, Milan, Italy and Director Personalized Medicine Asthma & Allergy Center at Humanitas Research Hospital IRCCS-Milano Italy since December 2016. He is known for his research work related to innovative treatment strategies for allergic diseases which includes biological response modifier in form of targeted immunotherapy with primary emphasis on sublingual immunotherapy (SLIT). He has served as Secretary General and President elect of World Allergy Organisation for six consecutive years and has served as president of the same organization during 2007–09. He is also the vice-president of INTERASMA.

Sally Ellen Wenzel–Morganroth is an American pulmonologist. She is a professor and Rachel Carson Chair of Environmental Health at the University of Pittsburgh Graduate School of Public Health. Wenzel was formally the co-director of the Harry and Jeanette Weinberg Clinical Research Unit at National Jewish Medical and Research Center.

<span class="mw-page-title-main">Asthma trigger</span> Factor that provokes symptoms of asthma

Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. An asthma attack is characterized by an obstruction of the airway, hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the respiratory tract. Its symptoms include a wide range of manifestations such as breathlessness, coughing, a tight chest and wheezing.

Mimi Tang is an Australian immunologist allergist specialized in food oral immunotherapy, such as pairing exposure to peanut proteins with probiotics. She is a professor at the Murdoch Children's Research Institute.

References

  1. ↑ "Governor General" (PDF).
  2. ↑ Chung, J.; Shin, K.; Lee, K. (2006). "Effect of Feedback Education of a Respiratory Service Program(RSP) on Inhaler". Journal of Allergy and Clinical Immunology. 117 (2): S192. doi:10.1016/j.jaci.2005.12.761. ISSN   0091-6749.
  3. ↑ "Uni Melbourne". findanexpert.unimelb.edu.au.
  4. ↑ "ASCIA Committees and Working Parties – Australasian Society of Clinical Immunology and Allergy (ASCIA)". www.allergy.org.au. Retrieved 2024-07-20.
  5. ↑ "Uni Melbourne". findanexpert.unimelb.edu.au. Retrieved 2024-07-20.
  6. ↑ "Meet the Team – AusPIPS Advisory panel". www.auspips.org.au. Retrieved 2024-07-20.
  7. ↑ "Prof Jo Douglass | Melbourne Allergy Asthma & Immunology Specialists". Melbourne Allergy Asthma & Immunology Consultants. Retrieved 2024-07-20.
  8. ↑ "Meet the Team – AusPIPS Advisory panel". www.auspips.org.au. Retrieved 2024-07-20.
  9. ↑ "Jo Douglass". scholar.google.com.au. Retrieved 2024-07-20.
  10. ↑ "Prof Jo Douglass | Melbourne Allergy | Parkville Allergy Asthma & Immunology". Parkville Allergy Asthma & Immunology Consultants. Retrieved 2024-07-20.
  11. ↑ Chatelier, Josh; Chan, Samantha; Tan, Ju Ann; Stewart, Alastair G.; Douglass, Jo Anne (2021-09-08). "Managing Exacerbations in Thunderstorm Asthma: Current Insights". Journal of Inflammation Research. 14: 4537–4550. doi: 10.2147/JIR.S324282 . hdl: 11343/287930 . PMC   8436255 . PMID   34526800.
  12. ↑ "Fast Facts: Asthma | Books Gateway | Karger Publishers". www.karger.com. Retrieved 2024-07-20.
  13. ↑ Thompson, Bruce R.; Douglass, Jo A.; Ellis, Matthew J.; Kelly, Vanessa J.; O'Hehir, Robyn E.; King, Gregory G.; Verbanck, Sylvia (2013). "Peripheral lung function in patients with stable and unstable asthma". The Journal of Allergy and Clinical Immunology. 131 (5): 1322–1328. doi:10.1016/j.jaci.2013.01.054. ISSN   1097-6825. PMID   23561802.
  14. ↑ Chua, Justin C.; Douglass, Jo A.; Gillman, Andrew; O'Hehir, Robyn E.; Meeusen, Els N. (2012). "Galectin-10, a potential biomarker of eosinophilic airway inflammation". PLOS ONE. 7 (8): e42549. Bibcode:2012PLoSO...742549C. doi: 10.1371/journal.pone.0042549 . ISSN   1932-6203. PMC   3412795 . PMID   22880030.
  15. ↑ Chen, Yan; Stirling, Rob G.; Paul, Eldho; Hore-Lacy, Fiona; Thompson, Bruce R.; Douglass, Jo A. (2011). "Longitudinal decline in lung function in patients with primary immunoglobulin deficiencies". The Journal of Allergy and Clinical Immunology. 127 (6): 1414–1417. doi:10.1016/j.jaci.2011.03.041. ISSN   1097-6825. PMID   21546068.
  16. ↑ Douglass, Jo A.; Goeman, Dianne P.; McCarthy, Edwina A.; Sawyer, Susan M.; Aroni, Rosalie A.; Stewart, Kay; Abramson, Michael J. (2012). "Over-the-counter β2-agonist purchase versus script: a cross-sectional study". Respiratory Medicine. 106 (2): 223–229. doi:10.1016/j.rmed.2011.09.012. ISSN   1532-3064. PMID   22040532.
  17. ↑ Gillman, A.; Douglass, Jo A. (2010). "What do asthmatics have to fear from food and additive allergy?". Clinical and Experimental Allergy. 40 (9): 1295–1302. doi:10.1111/j.1365-2222.2010.03528.x. ISSN   1365-2222. PMID   20528881.
  18. ↑ O'Hehir, Robyn E.; Gardner, Leanne M.; de Leon, Maria P.; Hales, Belinda J.; Biondo, Mark; Douglass, Jo A.; Rolland, Jennifer M.; Sandrini, Alessandra (2009-11-15). "House dust mite sublingual immunotherapy: the role for transforming growth factor-beta and functional regulatory T cells". American Journal of Respiratory and Critical Care Medicine. 180 (10): 936–947. doi:10.1164/rccm.200905-0686OC. ISSN   1535-4970. PMID   19696440.
  19. ↑ Physicians, The Royal Australasian College of, The Royal Australasian College of Physicians, The Royal Australasian College of Physicians, retrieved 2024-07-20
  20. ↑ "Fellow of TSANZ". The Thoracic Society of Australia & New Zealand. Retrieved 2024-07-20.
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