John Stamatoyannopoulos

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John A. Stamatoyannopoulos [1] a Greek-American physician-scientist in molecular biology and epigenomics. [2] He is a professor of genome sciences and medicine at the University of Washington, where he heads the Stam Lab and led UW Medicine's participation in the ENCODE project. [3] [4] John is the son of Greek geneticist George Stamatoyannopoulos. [5] Stamatoyannopoulos is the scientific director of the Altius Institute for Biomedical Sciences. [6] [7]

Academics and career

Stamatoyannopoulous attended Stanford University. He received an M.D. from the University of Washington School of Medicine before completing his medical studies at Harvard Medical School. [8] [9] He completed his fellowship in Oncology and Hematology at the Dana Farber Cancer Institute where he was awarded the Howard Hughes Medical Institute Physician postdoctoral fellowship. [10]

In 2005, Stamatoyannopoulos joined the Departments of Genome Sciences and Medicine at the University of Washington. He later served as the principal investigator leading the University's participation in the ENCODE project and as director of the Northwest Reference Epigenome Mapping Center. [11] He was a member of the editorial board of Genome Research and in 2009 was elected to the American Society for Clinical Investigation. [10] In 2015, the National Human Genome Research Institute awarded Dr. Stamatoyannopoulos $10 million to create a new Center of Excellence in Genomic Science, the Center for Photogenomics, with the focus of developing high speed imaging technology to replace traditional DNA sequencing methods. [12] [13]

Stamatoyannopoulos is a member of the ENCODE project, and in 2012 led the international ENCODE consortium in publishing a series of papers in Nature which promoted the significance of regulatory regions within the genome. [6] [14] His ENCODE research provided the first detailed map of gene controlling regulatory DNA and a dictionary of the genome's programming language—instructions written within the DNA. [15]

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References

  1. ↑ Stamatoyannopoulos, John A. (September 2012). "What does our genome encode?". Genome Research. 22 (9): 1602–1611. doi:10.1101/gr.146506.112. PMC   3431477 . PMID   22955972.
  2. ↑ Dunbar, Cynthia E.; Bodine, David M.; Nienhuis, Arthur W. (2018-08-01). "George Stamatoyannopoulos (1934–2018)". Molecular Therapy. 26 (8): 1871–1872. doi: 10.1016/j.ymthe.2018.07.004 . ISSN   1525-0016.
  3. ↑ "Decoding the Living Genome". UW Medicine Magazine. 2018-11-09. Retrieved 2020-06-11.
  4. ↑ "UW Genome Sciences: John Stamatoyannopoulos". www.gs.washington.edu. Retrieved 2020-06-08.
  5. ↑ "Young dreamer's early vision still influences his field". newsroom.uw.edu. 2019-09-25. Retrieved 2020-06-08.
  6. 1 2 Timmerman, Luke. "GlaxoSmithKline, Searching For Hit Drugs, Pours $95M Into DNA 'Dark Matter'". Forbes. Retrieved 2020-06-08.
  7. ↑ "Organization". www.altius.org. Retrieved 2021-02-22.
  8. ↑ "StamLab". www.stamlab.org. Retrieved 2020-06-08.
  9. ↑ "John Stamatoyannopoulos - The researcher who discovered double meaning in DNA". www.ellines.com. Retrieved 2020-06-08.
  10. 1 2 "Speakers - Big Data". www.nasonline.org. Retrieved 2020-06-11.
  11. ↑ "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results". projectreporter.nih.gov. Retrieved 2020-06-12.
  12. ↑ Stamatoyannopoulos, John. "Center for Photogenomics". Grantome.
  13. ↑ "Center of Excellence in Genomic Science". University of Washington. Retrieved 2020-06-12.
  14. ↑ Dunham, Ian; Kundaje, Anshul; Aldred, Shelley F.; Collins, Patrick J.; Davis, Carrie A.; Doyle, Francis; Epstein, Charles B.; Frietze, Seth; Harrow, Jennifer; Kaul, Rajinder; Khatun, Jainab (September 2012). "An integrated encyclopedia of DNA elements in the human genome". Nature. 489 (7414): 57–74. Bibcode:2012Natur.489...57T. doi: 10.1038/nature11247 . ISSN   1476-4687. PMC   3439153 . PMID   22955616.
  15. ↑ "Millions of DNA switches that power human genome's operating system are discovered". EurekAlert!. Retrieved 2020-06-12.
  16. "Decoding the Human Genome" (PDF). McGill University Publications. Quebec, Canada: McGill University.
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