John Walker-Smith

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John Walker-Smith
EWS20.02 (cropped) John Walker-Smith.jpg
Walker-Smith in June 2002
NationalityAustralian
Occupation Gastroenterologist
Years active1985–2001
Employer University of London

John Walker-Smith is an Australian [1] gastroenterologist well known for his work in pediatrics. [2] From 1985 until his retirement in 2001, he was professor of pediatric gastroenterology at the University of London. [3] [4] He also formerly served as the editor-in-chief of the Journal of Pediatric Gastroenterology and Nutrition . [5]

MMR vaccine controversy

Walker-Smith is the senior co-author of a paper (along with Andrew Wakefield, the lead author) which claimed a unique gastrointestinal condition in autistic children that may be connected to the MMR vaccine. This study is generally regarded as sparking the MMR vaccine controversy. [6]

In 2010, Walker-Smith was found guilty by the General Medical Council of professional misconduct who recommended erasure subject to appeal. As a result, he was barred from practicing medicine. [4] [7] On appeal, the case heard by Mr. Justice Mitting in the High Court stated that the GMC determinations were superficial and inadequate and so were quashed. [8]

In a statement reported in the book on the fraud by Brian Deer, Walker-Smith said:

My case was related to entirely different issues to those that concerned Dr. Wakefield... Every investigative procedure I ordered was to find out what was wrong with the children. [9]

Related Research Articles

<span class="mw-page-title-main">MMR vaccine</span> Any of several combined vaccines against measles, mumps, and rubella

The MMR vaccine is a vaccine against measles, mumps, and rubella, abbreviated as MMR. The first dose is generally given to children around 9 months to 15 months of age, with a second dose at 15 months to 6 years of age, with at least four weeks between the doses. After two doses, 97% of people are protected against measles, 88% against mumps, and at least 97% against rubella. The vaccine is also recommended for those who do not have evidence of immunity, those with well-controlled HIV/AIDS, and within 72 hours of exposure to measles among those who are incompletely immunized. It is given by injection.

<i>The Lancet</i> Peer-reviewed general medical journal

The Lancet is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also one of the world's highest-impact academic journal. It was founded in England in 1823.

<span class="mw-page-title-main">Richard Horton (editor)</span> British medical editor

Richard Charles Horton is editor-in-chief of The Lancet, a United Kingdom–based medical journal. He is an honorary professor at the London School of Hygiene and Tropical Medicine, University College London, and the University of Oslo.

<span class="mw-page-title-main">Brian Deer</span> British investigative journalist

Brian Deer is a British investigative journalist, best known for inquiries into the drug industry, medicine and social issues for The Sunday Times. Deer's investigative nonfiction book The Doctor Who Fooled the World, an exposé on disgraced former doctor Andrew Wakefield and the 1998 Lancet MMR autism fraud was published in September 2020 by Johns Hopkins University Press.

<span class="mw-page-title-main">Vaccine hesitancy</span> Reluctance or refusal to be vaccinated or have ones children vaccinated

Vaccine hesitancy is a delay in acceptance, or refusal, of vaccines despite the availability of vaccine services and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain about their use, or using certain vaccines but not others. The scientific consensus that vaccines are generally safe and effective is overwhelming. Vaccine hesitancy often results in disease outbreaks and deaths from vaccine-preventable diseases. Therefore, the World Health Organization characterizes vaccine hesitancy as one of the top ten global health threats.

Arthur Krigsman is a pediatrician and gastroenterologist best known for his controversial research in which he attempted to prove that the MMR vaccine caused diseases, especially autism. He specializes in the evaluation and treatment of gastrointestinal pathology in children with autism spectrum disorders, and has written in support of the diagnosis he calls autistic enterocolitis. The original study that tied the MMR vaccine to autism and GI complaints conducted by one of Krigsman's associates has been found to be fraudulent, and the diagnosis of "autistic enterocolitis" has not been accepted by the medical community.

Claims of a link between the MMR vaccine and autism have been extensively investigated and found to be false. The link was first suggested in the early 1990s and came to public notice largely as a result of the 1998 Lancet MMR autism fraud, characterised as "perhaps the most damaging medical hoax of the last 100 years". The fraudulent research paper, authored by discredited former doctor Andrew Wakefield and published in The Lancet, falsely claimed the vaccine was linked to colitis and autism spectrum disorders. The paper was retracted in 2010 but is still cited by anti-vaccine activists.

<span class="mw-page-title-main">Andrew Wakefield</span> Discredited British former doctor (born 1956)

Andrew Jeremy Wakefield is a British anti-vaccine activist, former physician, and discredited academic who was struck off the medical register for his involvement in The Lancet MMR autism fraud, a 1998 study that fraudulently claimed a link between the measles, mumps, and rubella (MMR) vaccine and autism. He has subsequently become known for anti-vaccination activism. Publicity around the 1998 study caused a sharp decline in vaccination uptake, leading to a number of outbreaks of measles around the world. He was a surgeon on the liver transplant programme at the Royal Free Hospital in London and became senior lecturer and honorary consultant in experimental gastroenterology at the Royal Free and University College School of Medicine. He resigned from his positions there in 2001, "by mutual agreement", then moved to the United States. In 2004, Wakefield co-founded and began working at the Thoughtful House research center in Austin, Texas, serving as executive director there until February 2010, when he resigned in the wake of findings against him by the British General Medical Council.

<span class="mw-page-title-main">Katherine O'Brien</span> Canadian-born pediatric physician (born 1963)

Katherine "Kate" L. O'Brien is a Canadian American pediatric infectious disease physician, epidemiologist, and vaccinologist who specializes in the areas of pneumococcal epidemiology, pneumococcal vaccine trials and impact studies, and surveillance for pneumococcal disease. She is also known as an expert in infectious diseases in American Indian populations. O’Brien is currently the Director of the World Health Organization's Department of Immunization, Vaccines and Biologicals.

<i>Cedillo v. Secretary of Health and Human Services</i> Legal case in US Court of Federal Claims, decided in 2009

Michelle Cedillo v. Secretary of Health and Human Services, also known as Cedillo, was a court case involving the family of Michelle Cedillo, an autistic girl whose parents sued the United States government because they believed that her autism was caused by her receipt of both the measles-mumps-and-rubella vaccine and thimerosal-containing vaccines. The case was a part of the Omnibus Autism Proceeding, where petitioners were required to present three test cases for each proposed mechanism by which vaccines had, according to them, caused their children's autism; Cedillo was the first such case for the MMR-and-thimerosal hypothesis.

Herman Hugh Fudenberg was an American clinical immunologist and the sole identified member of the Neuro Immuno Therapeutics Research Foundation (NITRF).

<span class="mw-page-title-main">Alessio Fasano</span> Medical doctor and researcher on celiac disease

Alessio Fasano is an Italian-born medical doctor, pediatric gastroenterologist and researcher. He currently holds many roles, including professor of pediatrics at Harvard Medical School and professor of nutrition at Harvard T.H. Chan School of Public Health, both in Boston. He serves as director of the Center for Celiac Research and Treatment at MassGeneral Hospital for Children (MGHfC) and co-director of the Harvard Medical School Celiac Research Program. In addition, he is director of the Mucosal Immunology and Biology Research Center at MGHfC, where he oversees a research program with approximately 50 scientists and staff researching a variety of acute and chronic inflammatory diseases, including cystic fibrosis, celiac disease, enteric infections and necrotizing enterocolitis. A common theme of these programs is the study of the emerging role of the gut microbiome in health and disease. Fasano is also the scientific director of the European Biomedical Research Institute of Salerno (EBRIS) in Italy. Along with these leadership positions, he is a practicing outpatient clinician in pediatric gastroenterology and nutrition and the division chief.

Shinjini Bhatnagar is an Indian pediatric gastroenterologist. She is elected as Fellow of National Academy of Sciences. Her research was recognised by the World Health Organization (WHO), and at 2nd World Congress of Pediatric Gastroenterology, Hepatology & Nutrition. She was awarded the Dr. ST Achar Gold Medal Award for Research in Child Health, and Hotam Tomar Gold Medal in recognition of her research in Pediatric Gastroenterology.

Margot Shiner was a German-British gastroenterologist and medical researcher who worked in London and Israel. As a result of her development of a new technique to biopsy the small intestine in children, she has been credited with launching the subspecialty of paediatric gastroenterology.

The Lancet MMR autism fraud centered on the publication in February 1998 of a fraudulent research paper titled "Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children" in The Lancet. The paper, authored by now discredited and deregistered Andrew Wakefield, and twelve coauthors, falsely claimed causative links between the MMR vaccine and colitis and between colitis and autism. The fraud was exposed in a lengthy Sunday Times investigation by reporter Brian Deer, resulting in the paper's retraction in February 2010 and Wakefield being struck off the UK medical register three months later. Wakefield reportedly stood to earn up to $43 million per year selling diagnostic kits for a non-existent syndrome he claimed to have discovered. He also held a patent to a rival vaccine at the time, and he had been employed by a lawyer representing parents in lawsuits against vaccine producers.

Extensive investigation into vaccines and autism spectrum disorder has shown that there is no relationship between the two, causal or otherwise, and that the vaccine ingredients do not cause autism. Vaccinologist Peter Hotez researched the growth of the false claim and concluded that its spread originated with Andrew Wakefield's fraudulent 1998 paper, with no prior paper supporting a link.

<span class="mw-page-title-main">Child development in India</span>

Child development in India is the Indian experience of biological, psychological, and emotional changes which children experience as they grow into adults. Child development has a significant influence on personal health and, at a national level, the health of people in India.

Joanne Katz is an epidemiologist, biostatistician, and Professor of International Health at the Johns Hopkins Bloomberg School of Public Health. She holds joint appointments in the Departments of Biostatistics, Epidemiology and Ophthalmology. Her expertise is in maternal, neonatal, and child health. She has contributed to the design, conduct and analysis of data from large community based intervention trials on nutritional and other interventions in Indonesia, Philippines, Bangladesh, Nepal and other countries.

JABS is a British pressure group launched in Wigan in January 1994. Beginning as a support group for the parents of children they claim became ill after the MMR vaccine, the group is currently against all forms of vaccination.

Deirdre Kelly is an Irish clinician, academic, and author. She is Professor of Paediatric Hepatology at the University of Birmingham and Clinical Lead for National Paediatric Hepatitis C Operational Delivery Network. She chairs the Board of Pension Trustees at the General Medical Council and is a non-executive director at NHS Blood and Transplant.

References

  1. Deer, Brian (2020). The Doctor Who Fooled the World: Science, Deception, and the War on Vaccines. Baltimore, MD: Johns Hopkins University Press. p. 367. ISBN   978-1-42143-800-9.
  2. Walker-Smith J A. Enduring Memories: A Pediatric Gastroenterologist Remembers. Second Edition 2012, The Memoir Club ISBN   978-1-84104-538-2
  3. Candy, David CA (November 2003). "Memoirs of John Walker-Smith". The Lancet. 362 (9396): 1683. doi:10.1016/S0140-6736(03)14821-0. S2CID   54306755.
  4. 1 2 "MMR doctor wins High Court appeal". BBC News. 7 March 2012. Retrieved 25 October 2015.
  5. "Editorial Announcement Regarding Professor John Walker-Smith". Journal of Pediatric Gastroenterology and Nutrition. 55 (2): 120. August 2012. doi: 10.1097/MPG.0b013e31825945cf .
  6. Wakefield, AJ; Murch, SH; Anthony, A; Linnell, J; Casson, DM; Malik, M; Berelowitz, M; Dhillon, AP; Thomson, MA; Harvey, P; Valentine, A; Davies, SE; Walker-Smith, JA (February 1998). "RETRACTED: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children". The Lancet. 351 (9103): 637–641. doi:10.1016/S0140-6736(97)11096-0. PMID   9500320. S2CID   439791.
  7. Burns, John F. (24 May 2010). "Council Bars Doctor Who Claimed Link Between Vaccines and Autism". The New York Times. ISSN   0362-4331 . Retrieved 2 October 2017.
  8. "MMR row: high court rules doctor should not have been struck off". 7 March 2012. Retrieved 25 April 2016.
  9. Deer, Brian (2020). The Doctor Who Fooled the World: Science, Deception, and the War on Vaccines. USA: Johns Hopkins University Press. p. 313. ISBN   978-1421438009.