Justine R. Smith

Justine R. Smith AM is an Australian ophthalmic surgeon and vision researcher. ^[1] Today she is based at Flinders University and Flinders Medical Centre in Adelaide, Australia. ^[2] Smith was awarded Member of the Order of Australia "for significant service to ophthalmology, particularly research and education" in the 2023 King's Birthday Honours. ^[3] She received the Flinders University Alumni Convocation Medal in 2022, ^[4] the Gold Medal of the International Ocular Inflammation Society in 2023, ^[5] and the Joanne Angle Service Award from the Association for Research in Vision and Ophthalmology in 2024. ^[6]

Career and achievements

• Gold Fellow of the Association for Research in Vision and Ophthalmology 2013 ^[7]
• President of the Association for Research in Vision and Ophthalmology Board of Trustees 2013-2014 ^[8]
• Elected Fellow of the Australian Academy of Health and Medical Sciences 2015 ^[9]
• Elected Chair of the Academia Ophthalmologica Internationalis 2015 ^[10]
• President of the American Uveitis Society 2015-2016
• Chair of the International Council of the International Ocular Inflammation Society 2015-2023 ^[11]
• Elected Fellow of the Academy of Asia-Pacific Professors of Ophthalmology 2017 ^[12]
• Superstar of STEM (Science and Technology Australia) 2017 ^[13]
• Executive Vice President of the Association for Research in Vision and Ophthalmology Board of Trustees 2017-2022 ^[8]
• Editor-in-Chief of Clinical and Experimental Ophthalmology 2020-2023: the first woman ever to lead a top-tier (Q1) ophthalmology journal ^[14]
• Investigator Grant (Leadership Level 3) from the National Heath and Medical Research Council 2024-2028 ^[15]

Selected publications

• Smith, Justine R.; Levinson, Ralph D.; Holland, Gary N. (2001). "Differential efficacy of tumor necrosis factor inhibition in the management of inflammatory eye disease and associated rheumatic disease". Arthritis Care and Research. 45: 252–257.
• Smith, Justine R.; Rosenbaum, James T.; Wilson, David J. (2002). "Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement" . Ophthalmology. 109 (9): P1709-1716. doi:10.1016/s0161-6420(02)01125-9.
• Smith, Justine R.; Braziel, Rita M.; Paoletti, Samantha (2003). "Expression of B-cell–attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma" . Blood. 101 (3): 815–821. doi:10.1182/blood-2002-05-1576.
• 2004 Susceptibility of retinal vascular endothelium to infection with Toxoplasma gondii tachyzoites.doi:10.1167/iovs.03-1105 Invest Ophthalmol Vis Sci
• 2005 A prospective trial of infliximab therapy for refractory uveitis: preliminary safety and efficacy outcomes. doi:10.1001/archopht.123.7.903 Arch Ophthalmol
• 2005 Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma. doi:10.1200/jco.2005.13.524 J Clin Oncol
• 2005 Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. doi:10.1016/j.ajo.2005.03.057 Am J Ophthalmol
• 2007 Therapy insight: scleritis and its relationship to systemic autoimmune disease. doi:10.1038/ncprheum0454 Nat Clin Pract Rheumatol
• 2008 Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. doi:10.1038/nature06765 Nature
• 2009 CCR3 is a target for age-related macular degeneration diagnosis and therapy. doi:10.1038/nature08151 Nature
• 2011 Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium. doi:10.1634/theoncologist.2011-0210 Oncologist
• 2012 Toxoplasma gondii tachyzoites cross retinal endothelium assisted by intercellular adhesion molecule-1 in vitro. doi:10.1038/icb.2012.21 Immunol Cell Biol
• 2012 Migration of Toxoplasma gondii-infected dendritic cells across human retinal vascular endothelium. doi:10.1167/iovs.12-10384 Invest Ophthalmol Vis Sci
• 2013 Role of the retinal vascular endothelial cell in ocular disease. doi:10.1016/j.preteyeres.2012.08.004 Prog Retin Eye Res
• 2013 Adalimumab therapy for refractory uveitis: results of a multicentre, open-label, prospective trial. doi:10.1136/bjophthalmol-2012-302292 Br J Ophthalmol
• 2014 Use of intravitreal rituximab for treatment of vitreoretinal lymphoma. doi:10.1136/bjophthalmol-2013-304043 Br J Ophthalmol
• 2015 Persistence of Ebola virus in ocular fluid during convalescence. doi:10.1056/nejmoa1500306 N Engl J Med
• 2017 Retinal pigment epithelial cells are a potential reservoir for Ebola virus in the human eye. doi:10.1167/tvst.6.4.12 Transl Vis Sci Technol
• 2018 Angiogenic and immunologic proteins identified by deep proteomic profiling of human retinal and choroidal vascular endothelial cells: potential targets for new biologic drugs. doi:10.1016/j.ajo.2018.03.020 Am J Ophthalmol
• 2018 Clinical manifestations and ophthalmic outcomes of ocular syphilis at a time of re-emergence of the systemic infection. doi:10.1038/s41598-018-30559-7 Sci Rep
• 2019 Revised criteria of International Workshop on Ocular Sarcoidosis (IWOS) for the diagnosis of ocular sarcoidosis. doi:10.1136/bjophthalmol-2018-313356 Br J Ophthalmol
• 2019 Current ophthalmology practice patterns for syphilitic uveitis. doi:10.1136/bjophthalmol-2018-313207 Br J Ophthalmol
• 2020 Managing uveitis during the COVID-19 pandemic. doi:10.1016/j.ophtha.2020.05.037 Ophthalmology
• 2020 T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. doi:10.1038/s41467-020-18961-0 Nat Commun
• 2021 Clinical manifestations and visual outcomes associated with ocular toxoplasmosis in a Brazilian population. doi:10.1038/s41598-021-82830-z Sci Rep
• 2021 Pathogenesis of ocular toxoplasmosis. doi:10.1016/j.preteyeres.2020.100882 Prog Retin Eye Res
• 2022 Brief Research Report: Ebola virus differentially infects human iris and retinal pigment epithelial cells. doi:10.3389/fviro.2022.892394 Front Virol
• 2022 Prevalence of toxoplasmic retinochoroiditis in an Australian adult population: a community-based study. doi:10.1016/j.oret.2022.04.022 Ophthalmol Retina
• 2023 Selective transcription factor blockade reduces human retinal endothelial cell expression of intercellular adhesion molecule-1 and leukocyte binding. doi:10.3390/ijms24043304 Int J Mol Sci
• 2023 Current practice in the management of ocular toxoplasmosis. doi:10.1136/bjophthalmol-2022-321091 Br J Ophthalmol
• 2024 Presentation, diagnostic testing and initial treatment of vitreoretinal lymphoma. doi:10.1016/j.oret.2023.08.012 Ophthalmol Retina
• 2024 Ocular manifestations of COVID-19. doi:10.1016/j.preteyeres.2024.101285 Prog Retin Eye Res
• 2024 Treatment of noninfectious uveitic macular edema with periocular and intraocular corticosteroid therapies: a report by the American Academy of Ophthalmology. doi:10.1016/j.ophtha.2024.02.019 Ophthalmology

References

1. "ORCID". orcid.org. Retrieved 2024-07-25.
2. Flinders University. "Professor Justine Smith".
3. "Kings birthday honours list 2023".
4. Flinders University (2022-11-24). "Forging a positive path for young clinicians". Flinders University Alumni Stories. Retrieved 2024-08-19.
5. IOIS 2023 Scientific Programme. "IOIS Opening Ceremony". www.iois.info. Retrieved 2024-08-21.
6. "The Association for Research in Vision and Ophthalmology- 2024 Angle Award: Justine Smith". www.arvo.org. Retrieved 2024-07-25.
7. The Association for Research in Vision and Ophthalmology. "2013 ARVO Fellows". www.arvo.org. Retrieved 2024-08-21.
8. "ARVO Joanne Angle award 2024".
9. Support, GO Creative (2022-01-28). "Fellowship | AAHMS". aahms.org. Retrieved 2024-07-25.
10. "A-O-INT.org - Academia Ophthalmologica Internationalis | Active Members" . Retrieved 2024-08-21.
11. International Ocular Inflammation Society. "IOIS History - Executive Boards". www.iois.info. Retrieved 2024-08-21.
12. Academy of Asia-Pacific Professors of Ophthalmology. "Fellows | AAPPO" . Retrieved 2024-08-21.
13. "Professor Justine Smith". Science and Technology Australia. Retrieved 2024-07-25.
14. Cartwright, Victoria A.; Smith, Justine R. (2024-03-07). "Women in ophthalmology" . Clinical & Experimental Ophthalmology. 52 (2): 133–134. doi:10.1111/ceo.14352. ISSN   1442-6404.
15. National Health & Medical Research Council (2024-08-21). "Investigator Grant applications for funding commencing in 2024" (PDF).