Karin Rodland

Last updated
Karin D. Rodland
Born1949
Alma mater Syracuse University
Known forcancer cell biology
Scientific career
Fields proteomics, systems biology
Institutions Pacific Northwest National Laboratory
Oregon Health & Science University
Thesis A comparative study of thermoregulatory responses to acute heat stress in three rodent species.  (1974)

Karin Dorinda Norlin Rodland (born 1949) is an American cancer cell biologist. She is a professor emeritus at Oregon Health and Science University.

Contents

Education

Rodland earned an A.B. from Hood College in 1970, and a PhD in biology from Syracuse University in 1974. She also completed her post-doctoral research at Syracuse with a National Cancer Institute Public Health Service Research Service Award. [1]

Career

Rodland began her academic career at Reed College in 1979, then Oregon Health and Science University School of Medicine in 1985. She was named a laboratory fellow at the U.S. Pacific Northwest National Laboratory, and a professor emeritus in Cell, Developmental and Cancer Biology, at Oregon Health and Science University School of Medicine. [1] [2] She retired in June 2020. [3]

Rodland serves on the board of directors for the U.S. Human Proteome Organization, [4] the editorial board of Cancer Biomarkers [5] and Cancer Genomics and Proteomics, [6] and on the Leadership Development Committee of the Federation of American Societies for Experimental Biology. [7] She was appointed to the Board of Directors of the Andy Hill Cancer Research Endowment (CARE) Fund by Washington State Governor Jay Inslee in 2022 [8] and served through June 2024.

Awards

Selected publications

Related Research Articles

<span class="mw-page-title-main">Proteomics</span> Large-scale study of proteins

Proteomics is the large-scale study of proteins. Proteins are vital macromolecules of all living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body.

<span class="mw-page-title-main">Pacific Northwest National Laboratory</span> Research institute

Pacific Northwest National Laboratory (PNNL) is one of the United States Department of Energy national laboratories, managed by the Department of Energy's (DOE) Office of Science. The main campus of the laboratory is in Richland, Washington, with additional research facilities around the country.

<span class="mw-page-title-main">Leroy Hood</span> American biologist (born 1938)

Leroy "Lee" Edward Hood is an American biologist who has served on the faculties at the California Institute of Technology (Caltech) and the University of Washington. Hood has developed ground-breaking scientific instruments which made possible major advances in the biological sciences and the medical sciences. These include the first gas phase protein sequencer (1982), for determining the sequence of amino acids in a given protein; a DNA synthesizer (1983), to synthesize short sections of DNA; a peptide synthesizer (1984), to combine amino acids into longer peptides and short proteins; the first automated DNA sequencer (1986), to identify the order of nucleotides in DNA; ink-jet oligonucleotide technology for synthesizing DNA and nanostring technology for analyzing single molecules of DNA and RNA.

<span class="mw-page-title-main">Victor Velculescu</span>

Victor E. Velculescu is a Professor of Oncology and Co-Director of Cancer Biology at Johns Hopkins University School of Medicine. He is internationally known for his discoveries in genomics and cancer research.

<span class="mw-page-title-main">Edison Liu</span>

Edison T. Liu is an American chemist who is the former president and CEO of The Jackson Laboratory, and the former director of its NCI-designated Cancer Center (2012-2021). Before joining The Jackson Laboratory, he was the founding executive director of the Genome Institute of Singapore (GIS), chairman of the board of the Health Sciences Authority, and president of the Human Genome Organization (HUGO) (2007-2013). As the executive director of the GIS, he brought the institution to international prominence as one of the most productive genomics institutions in the world.

Hui Zhang is a professor of Pathology at Johns Hopkins University. She specializes in analysis of glycoproteins and other protein modifications on the proteome scale. Her most cited article is Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

<span class="mw-page-title-main">Proteogenomics</span>

Proteogenomics is a field of biological research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of peptides. Proteogenomics is used to identify new peptides by comparing MS/MS spectra against a protein database that has been derived from genomic and transcriptomic information. Proteogenomics often refers to studies that use proteomic information, often derived from mass spectrometry, to improve gene annotations. The utilization of both proteomics and genomics data alongside advances in the availability and power of spectrographic and chromatographic technology led to the emergence of proteogenomics as its own field in 2004.

Richard Dale Smith is a chemist and a Battelle Fellow and chief scientist within the biological sciences division, as well as the director of proteomics research at the Pacific Northwest National Laboratory (PNNL). Smith is also director of the NIH Proteomics Research Resource for Integrative Biology, an adjunct faculty member in the chemistry departments at Washington State University and the University of Utah, and an affiliate faculty member at the University of Idaho and the Department of Molecular Microbiology & Immunology, Oregon Health & Science University. He is the author or co-author of approximately 1100 peer-reviewed publications and has been awarded 70 US patents.

<span class="mw-page-title-main">Barbara Wold</span> Professor of Molecular Biology

Barbara J. Wold is the Bren Professor of Molecular Biology, the principal investigator of the Wold Lab at the California Institute of Technology (Caltech) and the principal investigator of the Functional Genomics Resource Center at the Beckman Institute at Caltech. Wold was director of the Beckman Institute at Caltech from 2001 to 2011.

Zeng Rong is a Chinese biochemist researching and developing technology for proteomics research. She is currently a professor at the Institute of Biochemistry and Cell Biology at the Shanghai Institutes for Biological Sciences.

David Fenyö is a Hungarian-Swedish-American computational biologist, physicist and businessman. He is currently professor in the Department of Biochemistry and Molecular Pharmacology at NYU Langone Medical Center. Fenyö's research focuses on the development of methods to identify, characterize and quantify proteins and in the integration of data from multiple modalities including mass spectrometry, sequencing and microscopy.

<span class="mw-page-title-main">Nevan Krogan</span> Canadian molecular and systems biologist

Nevan J. Krogan is a Canadian molecular and systems biologist. He is a professor and the Director of the Quantitative Biosciences Institute (QBI) at the University of California San Francisco (UCSF), as well as a senior investigator at the J. David Gladstone Institutes.

Kumaravel Somasundaram is an Indian cancer biologist and a professor at the Department of Microbiology and Cell Biology of the Indian Institute of Science. Known for his studies on the therapeutics of Glioblastoma, Somasunderam is an elected fellow of all the three major Indian science academies namely, the National Academy of Sciences, India, the Indian Academy of Sciences and the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2006.

Christine Vogel is a German-American molecular biologist who is an associate professor at the New York University. Her research considers quantitative proteomics. She is particularly interested in protein expression patterns and how these are related to human disease.

G.V. Shivashankar is an Indian biophysicist working in the field of Mechanobiology. His research focuses on understanding the coupling between cell mechanics and genome organization for the regulation of cell homeostasis and cell state transitions. In addition his group also developed imaging-AI based chromatin biomarkers as fingerprints for cells in health and disease. Towards this, his group employs multi-scale correlative bio-imaging methods combined with bioengineered interfaces, functional genomics, theoretical modeling, and machine learning. He currently holds a full professorship for Mechano-Genomics at the Department of Health Sciences and Technology at ETH Zurich and he also heads the Laboratory of Nanoscale Biology at the Paul Scherrer Institute.

Amanda Grace Paulovich is an oncologist, and a pioneer in proteomics using multiple reaction monitoring mass spectrometry to study tailored cancer treatment.

Lisa M. Coussens is an American cancer scientist who is Professor and Chair of the Department of Cell, Developmental and Cancer Biology and Deputy Director for Basic and Translational Research in the Knight Cancer Institute at the Oregon Health & Science University. She served as 2022-2023 President of the American Association for Cancer Research.

<span class="mw-page-title-main">Olga Ornatsky</span> Canadian Scientist

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Yu-Ju Chen is a Taiwanese proteomics research scientist, who leads international projects in proteogenomics.

Nitzan Rosenfeld is a professor of Cancer Diagnostics at the University of Cambridge. He is a Senior Group Leader at the Cancer Research UK Cambridge Institute and co-founder of Inivata, a clinical cancer genomics company.

References

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  2. "Karin Rodland Ph.D. | OHSU People | OHSU". www.ohsu.edu. Retrieved 2022-06-13.
  3. "A Career in Cancer Research Ends with Long-Awaited Experiments | PNNL". www.pnnl.gov. Retrieved 2022-06-13.
  4. "US HUPO - Board of Directors". www.ushupo.org. Retrieved 2022-06-11.
  5. "Cancer Biomarkers". IOS Press. Retrieved 2022-06-13.
  6. "Editorial Board of Cancer Genomics & Proteomics 2022 | Cancer Genomics & Proteomics". cgp.iiarjournals.org. Retrieved 2022-06-13.
  7. "LDC Committee Home". ffvp.memberclicks.net. Retrieved 2022-06-11.
  8. "Recent Appointments: Governor Jay Inslee". www.governor.wa.gov. Retrieved 2022-06-11.
  9. "News". CARE Fund. Retrieved 2022-06-13.
  10. "Recognized Leader and Mentor Dr. Robert J. Mayer Receives Distinguished Achievement Award". Default Digital Object Group. 2019-05-13. doi:10.1200/adn.19.190221. S2CID   240684358 . Retrieved 2022-06-11.
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  13. "PNNL: Karin Rodland selected as Laboratory Fellow". www.pnnl.gov. Retrieved 2022-06-11.
  14. Mass spectometry and biomarker development. Karin D. Rodland. Amsterdam: IOS Press. 2005. ISBN   1-58603-461-8. OCLC   156786281.{{cite book}}: CS1 maint: others (link)
  15. Zhang, Hui; Liu, Tao; Zhang, Zhen; Payne, Samuel H.; Zhang, Bai; McDermott, Jason E.; Zhou, Jian-Ying; Petyuk, Vladislav A.; Chen, Li; Ray, Debjit; Sun, Shisheng (2016). "Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer". Cell. 166 (3): 755–765. doi:10.1016/j.cell.2016.05.069. PMC   4967013 . PMID   27372738.
  16. Vasaikar, Suhas; Huang, Chen; Wang, Xiaojing; Petyuk, Vladislav A.; Savage, Sara R.; Wen, Bo; Dou, Yongchao; Zhang, Yun; Shi, Zhiao; Arshad, Osama A.; Gritsenko, Marina A. (2019). "Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities". Cell. 177 (4): 1035–1049.e19. doi:10.1016/j.cell.2019.03.030. PMC   6768830 . PMID   31031003.
  17. Systems biology of biomarkers. Karin D. Rodland. IOS Press. 2010. ISBN   978-1-60750-584-6. OCLC   669738858.{{cite book}}: CS1 maint: others (link)