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KoVariome is the variome of Korean ethnic groups. It was initiated in 2010 when the Genome Research Foundation in Korea was established. KoVariome has produced around 100 Korean genome diversity data on 4 April 2018 in Scientific Reports [1] and 1,094 Korean genome variation information on 27 May 2020. [2]
Koreans are an East Asian ethnic group native to Korea. The majority of Koreans live in the two Korean nation states of North and South Korea, which are collectively referred to as Korea. As of 2021, an estimated 7.3 million ethnic Koreans resided outside of Korea. Koreans are also an officially recognized ethnic minority in other Asian countries, including China, Japan, Kazakhstan, Russia, and Uzbekistan. Outside of Asia, sizeable Korean communities have formed in Germany, the United Kingdom, France, the United States, Canada, and Oceania.
The variome is the whole set of genetic variations found in populations of species that have gone through a relatively short evolution change. For example, among humans, about 1 in every 1,200 nucleotide bases differ. The size of human variome in terms of effective population size is claimed to be about 10,000 individuals. This variation rate is comparatively small compared to other species. For example, the effective population size of tigers which perhaps has the whole population size less than 10,000 in the wild is not much smaller than the human species indicating a much higher level of genetic diversity although they are close to extinction in the wild. In practice, the variome can be the sum of the single nucleotide polymorphisms (SNPs), indels, and structural variation (SV) of a population or species. The Human Variome Project seeks to compile this genetic variation data worldwide. Variomics is the study of variome and a branch of bioinformatics.
The Korean Bioinformation Center (KOBIC) is the Korean national research centre in bioinformatics, based in Daejeon, South Korea. The centre is comparable to the National Center for Biotechnology Information (NCBI) in the United States and the European Bioinformatics Institute (EBI) in Europe and plays a key role in various areas such as genomics, proteomics, systems biology, and personalized medicine.
Cyclic AMP-responsive element-binding protein 3 is a protein that in humans is encoded by the CREB3 gene.
The Jinju Formation is an Early Cretaceous geologic formation in South Korea. Dinosaur remains are among the fossils that have been recovered from the formation, although none have yet been referred to a specific genus. The depositional age of this formation spans from approximately 112.4 ± 1.3 to 106.5 million years ago based on detrital zircon U-Pb dating. It predominantly consists of black shale, with sandstone packets, deposited in a fluvial-lacustrine setting.
Dieckol is a phlorotannin that can be found in arame, in Ecklonia cava or in Ecklonia stolonifera.
The Korea Invisible Mass Search (KIMS), is a South Korean experiment, led by Sun Kee Kim, searching for weakly interacting massive particles (WIMPs), one of the candidates for dark matter. The experiments use CsI(Tl) crystals at Yangyang Underground Laboratory (Y2L), in tunnels from a preexisting underground power plant. KIMS is supported by the Creative Research Initiative program of the Korea Science and Engineering Foundation. It is the first physics experiment located, and largely built, in Korea.
ParaHoxozoa is a clade of animals that consists of Bilateria, Placozoa, and Cnidaria. The relationship of this clade relative to the two other animal lineages Ctenophora and Porifera is debated. Some phylogenomic studies have presented evidence supporting Ctenophora as the sister to Parahoxozoa and Porifera as the sister group to the rest of animals. Some studies have presented evidence supporting Porifera as the sister to Parahoxozoa and Ctenophora as the sister group to the rest of animals.
The Good Wife is a South Korean television series starring Jeon Do-yeon, Yoo Ji-tae and Yoon Kye-sang. It is a Korean drama remake of the American television series of the same title which aired on CBS from 2009 to 2016. It replaced Dear My Friends and aired on the cable network tvN every Fridays and Saturdays at 20:30 (KST) for 16 episodes from July 8 to August 27, 2016.
Donna R. Maglott is a staff scientist at the National Center for Biotechnology Information known for her research on large-scale genomics projects, including the mouse genome and development of databases required for genomics research.
Tunnel is a 2017 South Korean television series starring Choi Jin-hyuk, Yoon Hyun-min and Lee Yoo-young. It replaced Voice and aired on cable network OCN on Saturdays and Sundays in the 22:00 (KST) time slot from March 25 to May 21, 2017 for 16 episodes. The series was inspired by the Hwaseong serial murders.
YoungSoo Kim is a South Korean chemist. Kim is an associate professor in Department of Pharmacy at Yonsei University.
Untouchable (Korean: 언터처블) is a 2017 South Korean television series starring Jin Goo, Kim Sung-kyun, Jung Eun-ji and Go Joon-hee. It aired from November 24, 2017 to January 20, 2018 on JTBC's Fridays and Saturdays at 23:00 (KST) time slot for 16 episodes.
Suits is a 2018 South Korean television series starring Jang Dong-gun and Park Hyung-sik. The drama is based on the American television series of the same name by Aaron Korsh. It aired on KBS2 starting April 25, 2018 on Wednesdays and Thursdays at 22:00 (KST) time slot for 16 episodes.
This article explains the genetic makeup and population history of East Asian peoples and their connection to genetically related populations, as well as Oceanians and partly, Central Asians and South Asians, which are collectively referred to as "East Eurasians" in population genomics.
Jo Jin-ho, commonly known by the mononym Jinho, is a South Korean singer, lyricist, dancer, composer, vocal coach and member of South Korean boy group Pentagon under Cube Entertainment. He is a former SM Entertainment trainee and member of the project group SM the Ballad. After leaving SM Entertainment in 2015, Jinho became a vocal coach. Since then, he has trained Cube labelmates (G)I-dle and Yoo Seon-ho, among others.
Aestuariicella is a rod-shaped, Gram-negative, and strictly aerobic genus of bacteria from the order Alteromonadales with one known species. Aestuariicella hydrocarbonica was first isolated in 2015 from oil spill contaminated tidal flat sediments from the Dangjin bay in Korea. Due to the recent nature of its discovery, its taxonomic classification has not yet been accepted. Future research into its evolutionary history and genome may change the naming of this organism.
Korean Genome Project (KGP) is the largest Korean Genome Project which currently includes over 10,000 human genomes sequenced in Korea by April 2021. KGP was originated from the national initiative of sequencing the reference Korean and whole population genomes in 2006 by KOBIC, KRIBB and NCSRD, KRISS, Daejeon in Korea. From 2009, KGP was supported by the Genome Research Foundation and TheragenEtex to build the Variome of Koreans as well as the Korean Reference Genome (KOREF). Starting from KOREF, a consensus variome reference, providing information on millions of variants from 40 additional ethnically homogeneous genomes from the Korean Personal Genome Project was completed in 2017. Updating the technology an improved version of KOREF was then constructed using long-read sequencing data produced by Oxford Nanopore PromethION and PacBio technologies has been released showcasing newer assembly technologies and techniques. In 2022 a new chromosome-level haploid assembly of KOREF was published, assembled using Oxford Nanopore Technologies PromethION, Pacific Biosciences HiFi-CCS, and Hi-C technology.
Jung-Min Lee is a South Korean-American medical oncologist and physician-scientist focused on the early clinical drug development and translational studies of targeted agents in BRCA mutation-associated breast or ovarian cancer, high-grade epithelial ovarian cancer, and triple-negative breast cancer. She is a NIH Lasker Clinical Research Scholar and principal investigator in the Women's Malignancies Branch at the National Cancer Institute.
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