Larry J. Anderson

Last updated

Larry J. Anderson (born July 29, 1947) is an American virologist who served in leadership positions at the Centers for Disease Control and Prevention (CDC) for more than three decades. He was director of the Division of Viral Diseases in the National Center for Immunization and Respiratory Diseases at the CDC (2006–2010), and chief of the Respiratory and Enteric Viruses Branch of the CDC Division of Viral and Rickettsial Diseases (1982–2006). From 2003 to 2006, Anderson led the CDC’s Post-Outbreak SARS Program, and he served as a special advisor on smallpox in the Office of the Associate Director for Terrorism, Preparedness, and Response. [1]

Contents

He is now professor and Marcus Chair of Infectious Diseases and co-director of the Pediatric Infectious Diseases Division of the Emory University School of Medicine, and a virologist in the Vaccine and Treatment Evaluation Unit of Emory Clinical Trials. [2] [3]

Anderson’s current vaccine-development research is focused on the immunopathogensis of respiratory viral infections, especially Respiratory Syncytial Virus (RSV), an important cause of morbidity and mortality in young children and the elderly globally. His laboratory, which collaborates with the Asthma Research Center at the Vanderbilt University Medical Center, is also studying the asthmatic immune response to RSV to identify novel approaches to treatment.

Publications

He is the co-author of more than 250 articles in peer-reviewed publications, [4] [5] the co-editor of five books, [6] and the co-author of nearly 70 review articles and book chapters. His awards include the CDC Lifetime Scientific Achievement Award, the William C. Watson Medal of Excellence, and the Charles C. Shepard Science Award.

Education

Anderson graduated from St. Olaf College and Harvard Medical School, and he received post-graduate training at Harbor General Hospital in Torrance, CA, the CDC in Atlanta, Beth Israel Hospital in Boston, and the Weatherall Institute of Molecular Medicine at John Radcliffe Hospital at Oxford University in England.

Related Research Articles

<span class="mw-page-title-main">Respiratory syncytial virus</span> Species of a virus

Respiratory syncytial virus (RSV), also called human respiratory syncytial virus (hRSV) and human orthopneumovirus, is a common, contagious virus that causes infections of the respiratory tract. It is a negative-sense, single-stranded RNA virus. Its name is derived from the large cells known as syncytia that form when infected cells fuse.

<i>Human metapneumovirus</i> Species of virus

Human metapneumovirus (HMPV) is a negative-sense single-stranded RNA virus of the family Pneumoviridae and is closely related to the Avian metapneumovirus (AMPV) subgroup C. It was isolated for the first time in 2001 in the Netherlands by using the RAP-PCR technique for identification of unknown viruses growing in cultured cells. It is the second most common cause after Respiratory syncytial virus (RSV) of lower respiratory infection in young children.

The National Institute of Allergy and Infectious Diseases is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

<span class="mw-page-title-main">Human parainfluenza viruses</span> Viruses that cause human parainfluenza

Human parainfluenza viruses (HPIVs) are the viruses that cause human parainfluenza. HPIVs are a paraphyletic group of four distinct single-stranded RNA viruses belonging to the Paramyxoviridae family. These viruses are closely associated with both human and veterinary disease. Virions are approximately 150–250 nm in size and contain negative sense RNA with a genome encompassing about 15,000 nucleotides.

Viral pneumonia is a pneumonia caused by a virus. Pneumonia is an infection that causes inflammation in one or both of the lungs. The pulmonary alveoli fill with fluid or pus making it difficult to breathe. Pneumonia can be caused by bacteria, viruses, fungi or parasites. Viruses are the most common cause of pneumonia in children, while in adults bacteria are a more common cause.

Gregory Antone Prince is an American pathology researcher, businessman, author, social critic, and historian of the Latter Day Saint movement.

Palivizumab, sold under the brand name Synagis, is a monoclonal antibody produced by recombinant DNA technology used to prevent severe disease caused by respiratory syncytial virus (RSV) infections. It is recommended for infants at high-risk for RSV due to conditions such as prematurity or other medical problems including heart or lung diseases.

Frederick A. Murphy is a retired American virologist. He was a member of the team of scientists that discovered the Ebola virus at the Centers for Disease Control and Prevention (CDC), where he served as Chief of Viropathology, near Emory University in Atlanta, Georgia, in 1976, and is internationally known for his work on rabies, encephalitis and hemorrhagic fevers, with over 250 peer-reviewed journal articles. Murphy was as an electron microscopy pioneer in the field of virology, best recognized for obtaining the first electron micrograph of an Ebola viral particle at the CDC in 1976.

<span class="mw-page-title-main">Vaccine Research Center</span>

The Vaccine Research Center (VRC), is an intramural division of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), US Department of Health and Human Services (HHS). The mission of the VRC is to discover and develop both vaccines and antibody-based products that target infectious diseases.

<span class="mw-page-title-main">Katherine O'Brien</span> Canadian-born pediatric physician (born 1963)

Katherine "Kate" L. O'Brien is a Canadian American pediatric infectious disease physician, epidemiologist, and vaccinologist who specializes in the areas of pneumococcal epidemiology, pneumococcal vaccine trials and impact studies, and surveillance for pneumococcal disease. She is also known as an expert in infectious diseases in American Indian populations. O’Brien is currently the Director of the World Health Organization's Department of Immunization, Vaccines and Biologicals.

<span class="mw-page-title-main">Robert M. Chanock</span> American pediatrician and virologist

Robert Merritt Chanock was an American pediatrician and virologist who made major contributions to the prevention and treatment of childhood respiratory infections in more than 50 years spent at the National Institute of Allergy and Infectious Diseases.

<span class="mw-page-title-main">George Siber</span> Medical researcher and vaccine expert

George Rainer Siber is a medical researcher and vaccine expert with 47 years of experience in developing numerous vaccines, therapeutic antibodies, and diagnostic agents for infectious diseases.

<i>Orthopneumovirus</i> Genus of viruses

The genus Orthopneumovirus consists of pathogens that target the upper respiratory tract within their specific hosts. Every orthopneumovirus is characterized as host specific, and has a range of diseases involved with respiratory illness. Orthopneumoviruses can cause diseases that range from a less-severe upper-respiratory illness to severe bronchiolitis or pneumonia. Orthopneumoviruses are found among sheep, cows, and most importantly humans. In humans, the orthopneumovirus that specifically impacts infants and small children is known as human respiratory syncytial virus.

James Earl Crowe Jr. is an American immunologist and pediatrician as well as Professor of Pediatrics and Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center.

<span class="mw-page-title-main">Brian R. Murphy</span>

Brian R. Murphy is an American virologist and former co-chief of the Laboratory of Infectious Diseases at the National Institute of Allergy and Infectious Disease.

A respiratory syncytial virus vaccine is a vaccine which prevents infection by respiratory syncytial virus. As of 2021, no licensed vaccine against RSV exists.

Jason S. McLellan is a structural biologist, professor in the Department of Molecular Biosciences and Robert A. Welch Chair in Chemistry at The University of Texas at Austin who specializes in understanding the structure and function of viral proteins, including those of coronaviruses. His research focuses on applying structural information to the rational design of vaccines and other therapies for viruses, including SARS-CoV-2, the novel coronavirus that causes COVID-19. McLellan and his team collaborated with researchers at the National Institute of Allergy and Infectious Diseases’ Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein, which biotechnology company Moderna used as the basis for the vaccine mRNA-1273, the first COVID-19 vaccine candidate to enter phase I clinical trials in the U.S. At least three other vaccines use this modified spike protein: those from Pfizer and BioNTech; Johnson & Johnson and Janssen Pharmaceuticals; and Novavax.

NajlaAl-Sonboli is a pediatrician and the head of the Pediatric Department of Al-Sabeen Hospital for Maternity and Children in Sana’a. This hospital is the biggest tertiary referral pediatric hospital in Yemen and receives patients from Sana’a and surrounding areas, which includes people who are relocated due to war. She is a research partner at the Liverpool School of Tropical Medicine.

<span class="mw-page-title-main">Barney S. Graham</span>

Barney S. Graham is an American immunologist, virologist, and clinical trials physician. He is the deputy director of the Vaccine Research Center and the chief of the Viral Pathogenesis Laboratory. He was elected a member of the National Academy of Sciences in 2022.

<span class="mw-page-title-main">John R. Mascola</span> American Physician-Scientist

John R. Mascola is an American physician-scientist, immunologist and infectious disease specialist. He was the director of the Vaccine Research Center (VRC), part of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). He also served as a principal advisor to Anthony Fauci, director of NIAID, on vaccines and biomedical research affairs.

References

  1. Anderson, Larry J. (21 October 2005). "Escaping an Epidemic". Science. 310 (5747): 444–445. doi:10.1126/science.1117649. S2CID   178561996.
  2. "Larry J. Anderson, MD". vaccines.emory.edu. Retrieved 27 January 2019.
  3. "Atlanta Pediatric Research | Larry J Anderson, MD | Faculty | People | Emory + Children's + GT | Atlanta Pediatric Research Alliance". Pedsresearch.org. Retrieved 2019-06-11.
  4. "Larry J Anderson's research works | Emory University, GA (EU) and other places" . Retrieved 2019-06-11.
  5. "Larry J. Anderson - Semantic Scholar". www.semanticscholar.org. Retrieved 27 January 2019.
  6. Anderson, Larry J.; Graham, Barney S., eds. (27 January 2019). Challenges and Opportunities for Respiratory Syncytial Virus Vaccines. Springer-Verlag. ISBN   9783642389184 . Retrieved 27 January 2019 via www.springer.com.