Lewis Wendell Hackett (14 December 1884 - Washington, 28 April 1962) was an American physician who worked in Italy, Albania and South America to combat malaria.
Lewis Wendell Hackett (14 December 1884 - Washington, 28 April 1962) was an American physician who worked in Italy, Albania and South America to combat malaria.
Hackett graduated from Harvard Medical School in 1913. The following year he became part of the International Health Division of the Rockefeller Foundation, whose task was the eradication of certain diseases of particular social importance in different parts of the world. From 1914 to 1924 he worked in Central America. In 1924 he was transferred to Italy.
Hackett had the opportunity to collaborate with the Italian doctor Alberto Missiroli, at the Laboratory of Public Health of Rome, who was interested in the implementation of preventive measures for malaria control based on the control of mosquitoes. Together with Bartholomew Gosio, he founded the School of Malariology in Nettuno. He began to experiment with DDT against Anopheles mosquitoes, vectors of the disease.
In 1925, Hackett and Missiroli, with funding from the Rockefeller Foundation, started the work which led to the creation of the Istituto Superiore di Sanità. Hackett and Frederick W. Knipe led work in Albania to control Malaria where the British engineer, Betty Lindsay, was employed until 1939. [1]
In 1940, with the outbreak of World War II, Hackett left Italy to go to South America where he remained until 1949. Overall, Hackett worked in seventeen countries. He was the first editor of the American Journal of Tropical Medicine and Hygiene when it was created in 1952 and president of the American Society of Tropical Medicine and Hygiene (ASTMH) in 1959.
Brevet Colonel Sir (Samuel) Rickard Christophers was a British protozoologist and medical entomologist specialising in mosquitoes.
Sir Ronald Ross was a British medical doctor who received the Nobel Prize for Physiology or Medicine in 1902 for his work on the transmission of malaria, becoming the first British Nobel laureate, and the first born outside Europe. His discovery of the malarial parasite in the gastrointestinal tract of a mosquito in 1897 proved that malaria was transmitted by mosquitoes, and laid the foundation for the method of combating the disease.
Tropical medicine is an interdisciplinary branch of medicine that deals with health issues that occur uniquely, are more widespread, or are more difficult to control in tropical and subtropical regions.
Giovanni Battista Grassi was an Italian physician and zoologist, best known for his pioneering works on parasitology, especially on malariology. He was Professor of Comparative Zoology at the University of Catania from 1883, and Professor of Comparative Anatomy at Sapienza University of Rome from 1895 until his death. His scientific contributions covered embryological development of honey bees, on helminth parasites, the vine parasite phylloxera, on migrations and metamorphosis in eels, and on termites. He was the first to describe and establish the life cycle of the human malarial parasite, Plasmodium falciparum, and discovered that only female anopheline mosquitoes are capable of transmitting the disease. His works in malaria remain a lasting controversy in the history of Nobel Prizes, because a British army surgeon Ronald Ross, who discovered the transmission of malarial parasite in birds was given the 1902 Nobel Prize in Physiology or Medicine. But Grassi, who demonstrated the complete route of transmission of human Plasmodium, and correctly identified the types of malarial parasite as well as the mosquito vector, Anopheles claviger, was denied.
Plasmodium ovale is a species of parasitic protozoon that causes tertian malaria in humans. It is one of several species of Plasmodium parasites that infect humans, including Plasmodium falciparum and Plasmodium vivax which are responsible for most cases of malaria in the world. P. ovale is rare compared to these two parasites, and substantially less dangerous than P. falciparum.
A mosquito net is a type of meshed curtain that is circumferentially draped over a bed or a sleeping area, to offer the sleeper barrier protection against bites and stings from mosquitos, flies, and other pest insects, and thus against the diseases they may carry. Examples of such preventable insect-borne diseases include malaria, dengue fever, yellow fever, zika virus, Chagas disease and various forms of encephalitis, including the West Nile virus.
George Henry Falkiner Nuttall FRS was an American-British bacteriologist who contributed much to the knowledge of parasites and of insect carriers of diseases. He made significant innovative discoveries in immunology, about life under aseptic conditions, in blood chemistry, and about diseases transmitted by arthropods, especially ticks. He carried out investigations into the distribution of Anopheline mosquitoes in England in relation to the previous prevalence of malaria there. With William Welch he identified the organism responsible for causing gas gangrene.
Alexandre Joseph Émile Brumpt was a French parasitologist.
Ettore Marchiafava was an Italian physician, pathologist and neurologist. He spent most of his career as professor of medicine at the University of Rome. His works on malaria laid down the foundation for modern malariology. He and Angelo Celli were the first to elucidate living malarial parasites in human blood, and able to distinguish the protozoan parasites responsible for tertian and benign malaria. In 1885 they gave the formal scientific name Plasmodium for these parasites. They also discovered meningococcus as the causative agent of cerebral and spinal meningitis. Marchiafava was the first to describe syphilitic cerebral arteritis and degeneration of brain in an alcoholic patient, which is now eponymously named Marchiafava's disease. He gave a complete description of a genetic disease of blood now known Paroxysmal nocturnal hemoglobinuria or sometimes Strübing-Marchiafava-Micheli syndrome, in honour of the pioneer scientists. He was personal physician to three successive popes and also to House of Savoy. In 1913 he was elected to Senate of the Kingdom of Italy. He founded the first Italian anti-tuberculosis sanatorium at Rome. He was elected member of the Accademia dei Lincei, becoming its vice-president in 1933.
Mandayam Osuri Tirunarayana Iyengar was an Indian medical entomologist who worked on management of filaria and malaria vectors. He was employed as an entomologist in the Department of Malaria Research, Bengal. The mermithid parasite Romanomermis iyengari and the mosquito species Culex iyengari are named after him.
Sir Gordon Covell was a physician and a major general in the army of British India, and a leading global expert on Malaria disease control and eradication efforts in the middle of the 20th century. He was member of the expert committee on malaria set up by the WHO from 1948 to 1958, of which he served as the secretary. At that time, he was also an advisor to the British Ministry of Health and the Director of the Malaria Laboratory at Horton Hospital.
The American Society of Tropical Medicine and Hygiene (ASTMH) is an Arlington, Virginia-based non-profit organization of scientists, clinicians, students and program professionals whose longstanding mission is to promote global health through the prevention and control of infectious and other diseases that disproportionately afflict the global poor. ASTMH members work in areas of research, health care and education that encompass laboratory science, international field studies, clinical care and country-wide programs of disease control. The current organization was formed in 1951 with the amalgamation of the American Society of Tropical Medicine, founded in 1903, and the National Malaria Society, founded in 1941.
Mark Frederick Boyd (1889–1968) was an American physician and writer. He taught and performed research in public health. He went to work for the Rockefeller Foundation in 1921, and thereafter specialized in the study of malaria. He also wrote about the history of Florida.
Charles Brooke Worth was an American naturalist and virologist who worked as a professor at Swarthmore College, with the US Army during World War II, and then with the Rockefeller Foundation during the post-war period working on matters of public health and mosquito-borne diseases. He travelled around the world, including countries in Africa and Asia, and was the author of several books, including Manual of Tropical Medicine, A Naturalist in Trinidad, The Nature of Living Things, and Mosquito Safari: A Naturalist In Southern Africa, Of mosquitoes, moths, and mice.
Percy Cyril Claude Garnham CMG FRS, was a British biologist and parasitologist. On his 90th birthday, he was called the "greatest living parasitologist".
Anopheles claviger is a mosquito species found in Palearctic realm covering Europe, North Africa, northern Arabian Peninsula, and northern Asia. It is responsible for transmitting malaria in some of these regions. The mosquito is made up of a species complex consisting of An. claviger sensu stricto and An. petragnani Del Vecchio. An. petragnani is found only in western Mediterranean region, and is reported to bite only animals, hence, it is not involved in human malaria.
Mosquito-malaria theory was a scientific theory developed in the latter half of the 19th century that solved the question of how malaria was transmitted. The theory proposed that malaria was transmitted by mosquitoes, in opposition to the centuries-old medical dogma that malaria was due to bad air, or miasma. The first scientific idea was postulated in 1851 by Charles E. Johnson, who argued that miasma had no direct relationship with malaria. Although Johnson's hypothesis was forgotten, the arrival and validation of the germ theory of diseases in the late 19th century began to shed new lights. When Charles Louis Alphonse Laveran discovered that malaria was caused by a protozoan parasite in 1880, the miasma theory began to subside.
Anopheles sinensis is a species of mosquito that transmits malaria as well as lymphatic filariasis. It is regarded as the most important vector of these human parasitic diseases in Southeast Asia. It is the primary vector of vivax malaria in many regions. In China it also transmits the filalarial parasite, and arthropod roundworm. In Japan it is also a vector of a roundworm Setaria digitata in sheep and goats.
Andrea Crisanti is an Italian full professor of microbiology at the University of Padua. He previously was professor of Molecular Parasitology at Imperial College London. He is best known for the development of genetically manipulated mosquitoes with the objective to interfere with either their reproductive rate or the capability to transmit diseases such as malaria.
Arnoldo Gabaldón Carrillo was a physician, researcher and Venezuelan politician. He is recognized for his activism against malaria. His campaign against the disease reduced the number of cases in Venezuela to almost zero during the 1950s, giving place to more exploitable territory and population growth.
