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Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types of arthritis, other organs are also affected. Onset can be gradual or sudden.
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves, and blood. This may result in a low red blood cell count, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months.
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint, caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. The joint at the base of the big toe is affected (Podagra) in about half of cases. It may also result in tophi, kidney stones, or kidney damage.
Rheumatology is a branch of medicine devoted to the diagnosis and management of disorders whose common feature is inflammation in the bones, muscles, joints, and internal organs. Rheumatology covers more than 100 different complex diseases, collectively known as rheumatic diseases, which includes many forms of arthritis as well as lupus and Sjögren's syndrome. Doctors who have undergone formal training in rheumatology are called rheumatologists.
Allopurinol is a medication used to decrease high blood uric acid levels. It is specifically used to prevent gout, prevent specific types of kidney stones and for the high uric acid levels that can occur with chemotherapy. It is taken orally or intravenously.
Sir Alfred Baring Garrod was an English physician.
Rheumatoid vasculitis is skin condition that is a typical feature of rheumatoid arthritis, presenting as peripheral vascular lesions that are localized purpura, cutaneous ulceration, and gangrene of the distal parts of the extremities.
Allopurinol hypersensitivity syndrome(AHS) typically occurs in persons with preexisting kidney failure. Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal necrolysis. About 1 in 1000 patients receiving allopurinol are affected, and mortality rates have been reported to be between 20% and 25%.
1000minds is a web application for decision-making and conjoint analysis supplied by 1000minds Ltd since 2003.
The Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL) is a disease-specific patient-reported outcome measure which determines the effect rheumatoid arthritis has on a patient's quality of life. The RAQoL has 30 items with a yes and no response format and takes about six minutes to complete.
Tsai-Fan Yu was a Chinese-American physician, researcher, and the first woman to be appointed as a full professor at Mount Sinai School of Medicine. She helped to develop an explanation for the cause of gout and experimented with early drugs to treat the disease which are still in use today.
Paul-Peter Tak M.D. PhD FMedSci is an immunologist and academic specialising in the fields of internal medicine, rheumatology and immunology. Tak has been the President & CEO of Candel Therapeutics since September 2020.
Nicola Dalbeth is a New Zealand academic rheumatologist whose research focuses on understanding the impact and mechanisms of gout. She supports clinical and laboratory research programmes and holds dual appointments as a full professor at the University of Auckland and as a consultant for the Auckland District Health Board.
Dafna D. Gladman, MD, FRCPC, is a Canadian doctor and medical researcher working in the fields of psoriatic arthritis, systemic lupus erythematosus, and rheumatoid arthritis. She is a professor at the University of Toronto Faculty of Medicine and Senior Scientist at the Krembil Research Institute. She is Deputy Director, Centre for Prognosis Studies in the Rheumatic Diseases, Co-Director, Lupus Clinic, Toronto Western Hospital (TWH) and Director, Psoriatic Arthritis Program, Toronto Western Hospital.
Lars Klareskog is a Swedish physician, immunologist, and rheumatologist, known for research into the genetics of autoimmune diseases such as rheumatoid arthritis (RA).
Michelle Leech is the Deputy Dean of Medicine at Monash University and an academic clinician-scientist. Leech oversees the delivery of the Monash medical program and maintains an active research profile and clinical practice as a rheumatologist.
An antiarthritic is any drug used to relieve or prevent arthritic symptoms, such as joint pain or joint stiffness. Depending on the antiarthritic drug class, it is used for managing pain, reducing inflammation or acting as an immunosuppressant. These drugs are typically given orally, topically or through administration by injection. The choice of antiarthritic medication is often determined by the nature of arthritis, the severity of symptoms as well as other factors, such as the tolerability of side effects.
Fiona Marion Florence McQueen is a New Zealand rheumatologist, environmentalist and children's writer, and was a full professor at the University of Auckland before retiring to run a private herbalist practice in Glenorchy in Otago. She was New Zealand's first woman professor of rheumatology.
Josef Smolen is an Austrian rheumatologist and immunologist and professor emeritus at the Medical University of Vienna. Since 2018 he is chairman emeritus of the Department of Internal Medicine 3 and the Division of Rheumatology at the Medical University of Vienna and Vienna General Hospital and was the chairman of the 2nd Medical Department and Center for Diagnosis and Therapy of Rheumatic Diseases at the Lainz Hospital, now the Hietzing Clinic of the Vienna Health Association from 1989 to 2017.
Rebecca Grainger is a New Zealand academic rheumatologist, and is a full professor at the University of Otago, specialising in rheumatoid arthritis and osteoarthritis, and gout. She is also interested in the use of technology for medical education and digital health.
References
- 1 2 University of Otago, Christchurch. "Professor Lisa K Stamp". www.otago.ac.nz.
- ↑ "Professor Lisa Stamp – Health Research Council". www.hrc.govt.nz.
- ↑ "Research award for dedicated rheumatologist – Health Research Council". hrc.govt.nz.
- ↑ "NZ research influences international treatment for gout". New Zealand Doctor.
- ↑ Gibb, John (17 February 2018). "Otago gout researcher wins $20,000 award". Otago Daily Times Online News.
- ↑ "Royal Society Te Apārangi – Christchurch researcher easing the pain of gout". royalsociety.org.nz.
- ↑ University of Otago. "Research Awards - Past Recipients". www.otago.ac.nz. Retrieved 1 July 2021.
- ↑ "View our fellows". Royal Society Te Apārangi. Retrieved 29 August 2023.
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