Liss, Lyss or LISS may refer to
- Liss (band), a Danish musical group
- Liss (name), a given name and surname
- Liss, Hampshire, a village in England
- West Liss, the oldest part of Liss village
- Liss Forest, a hamlet near Liss
- Liss Athletic F.C., a semi-professional football club based in Liss
- Liss railway station, on the Portsmouth Direct Line
- Liss Forest Road railway station, a former station on the Longmoor Military Railway
- LISS panel (Longitudinal Internet Studies for the Social sciences), Netherlands
- Liss, a fictional town in stories of Russian writer Alexander Grin
- Lyss, a municipality in Switzerland
