This is a list of IUP Crimson Hawks football players in the NFL draft .
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| = Pro Bowler | |
| = Hall of Famer |
Source: [1]
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1970 | 8 | 2 | 184 | Dave Smith | Pittsburgh Steelers | WR |
| 1976 | 15 | 22 | 425 | Lynn Hieber | Cincinnati Bengals | QB |
| 1979 | 2 | 23 | 51 | Jim Haslett | Buffalo Bills | LB |
| 1996 | 5 | 20 | 152 | Chris Villarrial | Chicago Bears | G |
| 2000 | 3 | 20 | 82 | Leander Jordan | Carolina Panthers | T |
| 2005 | 7 | 12 | 226 | LeRon McCoy | Arizona Cardinals | WR |
| 2010 | 4 | 28 | 126 | Akwasi Owusu-Ansah | Dallas Cowboys | DB |