This is a list of Mississippi College Choctaws football players in the NFL draft .
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| = Pro Bowler | |
| = Hall of Famer |
Source: [1]
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1939 | 13 | 3 | 113 | Joel Hitt | Cleveland Rams | E |
| 1941 | 12 | 3 | 103 | Charlie Armstrong | Chicago Cardinals | B |
| 1976 | 14 | 15 | 390 | Larry Evans | Denver Broncos | LB |
| 1983 | 4 | 5 | 89 | Michael Williams | Philadelphia Eagles | RB |
| 7 | 11 | 179 | Daryl Posey | Kansas City Chiefs | RB | |
| 1985 | 11 | 16 | 296 | Harold Stanfield | Cincinnati Bengals | TE |
| 1991 | 6 | 15 | 154 | Fred McAfee | New Orleans Saints | RB |