This is a list of UC Riverside Highlanders football players in the NFL draft.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1974 | 4 | 24 | 102 | Frank Johnson | Los Angeles Rams | T |
| 9 | 13 | 221 | Derek Williams | Los Angeles Rams | DB | |
| 1976 | 3 | 8 | 68 | Russ Bolinger | Detroit Lions | T |
| 3 | 27 | 87 | Butch Johnson | Dallas Cowboys | WR | |
| 1978 | 1 | 24 | 24 | Dan Bunz | San Francisco 49ers | LB |
| 1979 | 4 | 28 | 110 | Calvin Sweeney | Pittsburgh Steelers | WR |