This is a List of Ambassadors of Spain to England and to the United Kingdom
Charles V, Holy Roman Emperor sent ambassadors to England representing the Empire, as well as Spain. When the Catholic Reformation began, Spain was in the opposite camp to Protestant England.
In the second half of the seventeenth century, Spain sometimes supported the English because, like them, it feared the hegemony in Europe that France and its king Louis XIV had achieved after the Treaty of the Pyrenees (1659).
After the Frenchman Philip of Anjou became King of Spain in 1700, during most of the eighteenth century, Spain again stood on the side of France, and was an opponent of Great Britain. It was not until the French Revolution that the two conservative countries, Spain and Great Britain, reconciled against the revolutionaries.