| Year | Title | Genre | Director | Character(s) | Actor | Notes | Country |
|---|---|---|---|---|---|---|---|
| 1927 | The Show | Silent Drama | Tod Browning | The Greek | Lionel Barrymore | n/a | USA |
| 1938 | Crime School | Crime Drama | Lewis Seiler | George "Fats" Papadopoulos, Nick Papadopoulos | Bernard Punsly Paul Porcasi | n/a | USA |
| 1944 | The Mask of Dimitrios | Mystery | Jean Negulesco | Dimitrios Makropoulos | Zachary Scott | n/a | USA |
| 1944 | Destination Tokyo | War | Delmer Daves | Leos Theofilos Karafias Jr aka "Tin Can" | Dane Clark | n/a | USA |
| 1951 | It's a Big Country | Anthology | Charles Vidor | Icarus Xenophon | Gene Kelly | n/a | USA |
| 1953 | Beneath the 12-Mile Reef | Drama | Robert D. Webb | Tony Petrakis | Robert Wagner | n/a | USA |
| 1954 | Ulysses | Drama | Mario Camerini Mario Bava | Ulysses | Kirk Douglas | n/a | Italy, USA, France |
| 1957 | Boy on a Dolphin | Romance Adventure | Jean Negulesco | Phaedra | Sophia Loren | n/a | USA |
| 1960 | Never on Sunday | Drama | Jules Dassin | Ilya | Melina Mercouri | n/a | Greece |
| 1960 | Spartacus | Epic | Stanley Kubrick | Spartacus | Kirk Douglas | n/a | USA |
| 1960 | Oceans 11 | Heist | Lewis Milestone | Spyros Acebos | Akim Tamiroff | n/a | USA |
| 1961 | The Guns of Navarone | War | J. Lee Thompson | Col Andrea Stavros Maria Pappadimos | Anthony Quinn Irene Pappas | n/a | UK, USA |
| 1962 | Phaedra | Drama | Jules Dassin | Phaedra Alexis | Melina Mercouri Anthony Perkins | n/a | USA, Greece |
| 1963 | America America | Drama | Elia Kazan | Various | Various | n/a | USA |
| 1964 | Zorba the Greek | Comedy-Drama | Michael Cacoyannis | Alexis Zorba | Anthony Quinn | n/a | USA, Greece |
| 1969 | A Dream of Kings | Drama | Daniel Mann | Matsoukas Caliope | Anthony Quinn Irene Pappas | n/a | USA |
| 1969 | The Arrangement | Drama | Elia Kazan | Evangelos Topouzoglou (aka "Eddie Anderson") | Kirk Douglas | n/a | USA |
| 1969 | Z | Drama | Costa-Gavras | Various | Various | n/a | France, Algeria |
| 1978 | The Greek Tycoon | Biographical Drama | J. Lee Thompson | Theo Tomasis | Anthony Quinn | n/a | USA |
| 1981 | The Postman Always Rings Twice | Drama | Bob Rafelson | Nick Papadakis | John Colicos | n/a | USA |
| 1985 | Eleni | Drama | Peter Yates | Eleni Gatzoyiannis Nicholas Gage | Kate Nelligan John Malkovich | n/a | USA |
| 1991 | Only the Lonely | Comedy | Chris Columbus | Nick Acropolis | Anthony Quinn | n/a | USA |
| 1998 | Lock, Stock and Two Smoking Barrels | Heist Comedy | Guy Ritchie | Nick "the Greek" | Stephen Marcus | n/a | UK |
| 1998 | The Big Lebowski | Heist Comedy | Coen Brothers | Theodore Donald "Donny" Kerabatsos | Steve Buscemi | n/a | USA |
| 2000 | 300 | War Epic | Zack Snyder | Leonidas | Gerard Butler | n/a | USA |
| 2002 | My Big Fat Greek Wedding | Comedy | Joel Zwick | Various | Various | n/a | USA, Canada |
| 2002 | Windtalkers | War Epic | John Woo | Corporal Milo "Greek" Pappas | Mark Ruffalo | n/a | USA |
| 2004 | Troy | Epic War | Wolfgang Petersen | Achilles Odysseus Agamemnon Menelaus | Brad Pitt Sean Bean Brian Cox Brendan Gleeson | n/a | USA, UK, Malta |
| 2009 | My Life in Ruins | Comedy | Donald Petrie | Georgia Ianakopolis | Nia Vardalos | n/a | USA, Greece, Spain |
| 2012 | Papadopoulos & Sons | Comedy-Drama | Marcus Markou | Various | Various | n/a | UK |
| 2020 | The Taverna | Comedy-Drama | Alkinos Tsilimidos | Various | Vangelis Mourikis | n/a | Australia |