Lumbrokinase

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Lumbrokinase
Identifiers
Organism Earthworm
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Lumbrokinase is a class of fibrinolytic enzymes [1] [2] present in earthworm species including Lumbricus bimastus [3] and Lumbricus rubellus . [2]

This enzyme was first discovered in 1991 in earthworm saliva. [2]

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References

  1. Hu, R. (2004). "Codon optimization, expression, and characterization of recombinant lumbrokinase in goat milk". Protein Expression and Purification. 37 (1): 83–8. doi:10.1016/j.pep.2004.05.018. PMID   15294284.
  2. 1 2 3 Mihara, Hisashi; Sumi, Hiroyuki; Yoneta, Tomoyuki; Mizumoto, Hideaki; Ikeda, Ryuzo; Seiki, Masao; Maruyama, Masugi (1991). "A novel fibrinolytic enzyme extracted from the earthworm, Lumbricus rubellus". The Japanese Journal of Physiology. 41 (3): 461–472. doi: 10.2170/jjphysiol.41.461 . PMID   1960890.
  3. Ge, T.; Sun, Z.; Fu, S.; Liang, G. (2005). "Cloning of thrombolytic enzyme (lumbrokinase) from earthworm and its expression in the yeast". Protein Expression and Purification. 42 (1): 20–8. doi:10.1016/j.pep.2005.04.005. PMID   15927482.