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Glycoproteins are proteins which contain oligosaccharide chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycosylation. Secreted extracellular proteins are often glycosylated.
Raymond Urgel Lemieux, CC, AOE, FRS was a Canadian organic chemist, who pioneered many discoveries in the field of chemistry, his first and most famous being the synthesis of sucrose. His contributions include the discovery of the anomeric effect and the development of general methodologies for the synthesis of saccharides still employed in the area of carbohydrate chemistry. He was a fellow of the Royal Society of Canada and the Royal Society (England), and a recipient of the prestigious Albert Einstein World Award of Science and Wolf Prize in Chemistry.
Chi-Huey Wong is a Taiwanese-American biochemist. He is currently the Scripps Family Chair Professor at the Scripps Research Institute, California in the department of chemistry. He is a member of the United States National Academy of Sciences, as awarded the 2014 Wolf Prize in Chemistry and 2015 RSC Robert Robinson Award. Wong is also the holder of more than 100 patents and publisher of more 700 scholarly academic research papers under his name.
Carolyn Ruth Bertozzi is an American chemist and Nobel laureate, known for her wide-ranging work spanning both chemistry and biology. She coined the term "bioorthogonal chemistry" for chemical reactions compatible with living systems. Her recent efforts include synthesis of chemical tools to study cell surface sugars called glycans and how they affect diseases such as cancer, inflammation, and viral infections like COVID-19. At Stanford University, she holds the Anne T. and Robert M. Bass Professorship in the School of Humanities and Sciences. Bertozzi is also an Investigator at the Howard Hughes Medical Institute (HHMI) and is the former director of the Molecular Foundry, a nanoscience research center at Lawrence Berkeley National Laboratory.
Anne Dell is an Australian biochemist specialising in the study of glycomics and the carbohydrate structures that modify proteins. Anne's work could be used to figure out how pathogens such as HIV are able to evade termination by the immune system which could be applied toward understanding how this occurs in fetuses. Her research has also led to the development of higher sensitivity mass spectroscopy techniques which have allowed for the better studying of the structure of carbohydrates. Anne also established GlycoTRIC at Imperial College London, a research center that allows for glycobiology to be better understood in biomedical applications. She is currently Professor of Carbohydrate Biochemistry and Head of the Department of Life Sciences at Imperial College London. Dell's other contributions to the study of Glycobiology are the additions she has made to the textbook "Essentials of Glycobiology" Dell was appointed Commander of the Order of the British Empire (CBE) in the 2009 Birthday Honours.
James Henderson Naismith is Professor of Structural Biology at the University of Oxford, former Director of the Research Complex at Harwell and Director of the Rosalind Franklin Institute. He previously served as Bishop Wardlaw Professor of Chemical Biology at the University of St Andrews. He was a member of Council of the Royal Society (2021-2022). He is currently the Vice-Chair of Council of the European X-ray Free Electron Laser and Vice-President (non-clinical) of The Academy of Medical Sciences. It has been announced that he will be the Head of the MPLS division at Oxford in the autumn of 2023.
Gideon John Davies is a Professor of Chemistry in the Structural Biology Laboratory (YSBL) at the University of York, UK. Davies is best known for his ground-breaking studies into carbohydrate-active enzymes, notably analysing the conformational and mechanistic basis for catalysis and applying this for societal benefit. In 2016 Davies was apppointed the Royal Society Ken Murray Research Professor at the University of York.
Harry Schachter FRSC is a Canadian biochemist and glycobiologist, and professor emeritus at the University of Toronto and the Hospital For Sick Children in Toronto, Canada.
Balaram Mukhopadhyay is an Indian Bengali carbohydrate chemist and a professor at the department of chemical sciences of the Indian Institute of Science Education and Research, Kolkata. Balaram is mainly known for his work in the field of synthetic carbohydrate chemistry. He was given the Excellence in Carbohydrate Research Award by the Association of Carbohydrate Chemists and Technologists India (ACCTI) in 2018 for his contribution towards field of carbohydrates.
Claire Eyers is a British biological mass spectrometrist who is professor of biological mass spectrometry at the University of Liverpool, where she heads up the Centre for Proteome Research. Her research publications list her either as Claire E Haydon or Claire E Eyers.
Sabine Flitsch is a German organic chemist and chemical biologist who holds a personal chair in Chemical Biology at the University of Manchester School of Chemistry, where she runs an active research glycobiology research group based in the Manchester Interdisciplinary Biocentre.
Pierre Sinaÿ, born on April 11, 1938, in Aulnay-sous-Bois (Seine-et-Oise), is a French organic chemist.
Ten Feizi is a Turkish Cypriot/British molecular biologist who is Professor and Director of the Glycosciences Laboratory at Imperial College London. Her research considers the structure and function of glycans. She was awarded the Society for Glycobiology Rosalind Kornfeld award in 2014. She was also awarded the Fellowship of the Academy of Medical Sciences in 2021.
Armando J. Parodi is an Argentine glycobiologist. He did his initial education at the School of Sciences of the University of Buenos Aires. His PhD work was done under Luis Federico Leloir, a recipient of the Nobel Prize in Chemistry for his work involving the finding of sugar nucleotides and how they play a role in the making of oligosaccharides and polysaccharides. He also pursued postdoc work at the Pasteur Institute in Paris, France and Duke University in Durham, NC, USA.
Katherine Jane Doores is a British biochemist who is a senior lecturer in the School of Immunology & Microbial Sciences at King's College London. During the COVID-19 pandemic Doores studied the levels of antibodies in patients who had suffered from COVID-19.
Tracey Maureen Gloster is a chemist at the University of St Andrews UK. Her research interests are in structural biology, chemical biology, glycobiology and carbohydrate processing enzymes.
Nicola Lucia B. Pohl is an American chemist who is the Joan & Marvin Carmack Chair at Indiana University Bloomington. She also serves as Associate Dean of Natural and Mathematical Sciences. Her research considers new approaches to make and analyse sugars. In 2020 she was elected a Fellow of the American Association for the Advancement of Science.
Elizabeth Fay Hounsell was a British Professor of Biological Chemistry, Birkbeck, University of London. She specialised in the role of protein glycosylation in cell regulation.
Rosalind Hauk Kornfeld (1935–2007) was a scientist at Washington University in St. Louis known for her research determining the structure and formation of oligosaccharides. The Society of Glycobiology annually awards a lifetime achievement award in her honor.
Athina Anastasaki is a Greek chemist who is a professor at ETH Zurich. Her research considers chemical synthesis and radical polymerisation. She was awarded the 2022 Ruzicka Prize in recognition of her research in chemistry.
References
- 1 2 "Professor Carmen Galan | 2021 Chemistry Biology Interface Division mid-career Award: Jeremy Knowles Award winner". Royal Society of Chemistry. Retrieved 2021-06-08.
- ↑ Bristol, University of. "Professor Carmen Galan". www.bristol.ac.uk. Retrieved 2021-06-08.
- ↑ Galan Hurtado, Maria del Carmen (2002). Conformationally constrained oligosaccharides as probes for carbohydrate-protein interactions. OCLC 53060274.
- ↑ "Professor M. Carmen Galan, School of Chemistry, University of Bristol". Imperial College London. Retrieved 2021-06-08.
- ↑ "Alumni". web.mit.edu. Retrieved 2021-06-08.
- 1 2 3 "Research Fellowships | School of Chemistry | University of Bristol". University of Bristol. Retrieved 2021-06-08.
- ↑ "Research". Galan Research Group. Retrieved 2021-06-08.
- ↑ "M. Carmen Galan". Elsevier. Retrieved 2021-06-08.
- ↑ "Dr. M. Carmen Galan - AcademiaNet". www.academia-net.org. Retrieved 2021-06-08.
- ↑ "ERC FUNDED PROJECTS". ERC: European Research Council. Retrieved 2021-06-08.
- ↑ "RSC Carbohydrate Chemistry Award". Royal Society of Chemistry. 16 May 2017. Retrieved 2021-06-08.
