The Medical Research Council (MRC) Laboratory of Medical Sciences (LMS) (formerly MRC Clinical Sciences Centre, and then the MRC London Institute of Medical Sciences) is a biomedical research institute based in West London, UK. Research at the institute focuses on the understanding of the molecular and physiological basis of health and disease. The LMS was established in 1994 and receives core funding from the Medical Research Council like the Laboratory of Molecular Biology at Cambridge University. The institute is partnered with Imperial College London at the Hammersmith Hospital, [1] [2] and is part of the Institute of Clinical Sciences (ICS), a department in the Imperial College London, Faculty of Medicine. It was led by Amanda Fisher from 2008-2021. In January 2023 the leadership was taken up by new director Wiebke Arlt.
The LMS carries out discovery science. Its research aims to understand the fundamental mechanisms that underpin health and disease. Its The three main areas of research focus at the LMS are 1. Genes and the Environment 2. Sex Differences and 3. Cell identity across the lifecourse. [3]
The LMS is based across a number of buildings at the Hammersmith Hospital campus in West London, UK. In 2017 a design team were appointed composed of Hawkins\Brown, Buro Happold and Abell Nepp to develop a new home for the Laboratory of Medical Sciences. [4] [5] In August 2018 contractors were invited to bid for the construction of the building. [6] In November a planning application was submitted to the London Borough of Hammersmith and Fulham. The new building will be based at the Hammersmith Hospital campus on the former cyclotron site, which was decommissioned and demolished in 2014. [7]
Imperial College London (Imperial) is a public research university in London, England. Its history began with Queen Victoria's husband, Prince Albert, who envisioned a cultural area in South Kensington that included museums, colleges, and the Royal Albert Hall. In 1907, these colleges – the Royal College of Science, the Royal School of Mines, and the City and Guilds of London Institute – merged to form the Imperial College of Science and Technology.
GKT School of Medical Education is the medical school of King's College London. The school has campuses at three institutions, Guy's Hospital (Southwark), King's College Hospital and St Thomas' Hospital (Lambeth) in London – with the initial of each hospital making up the acronymous name of the school. The school in its current guise was formed following a merger with the United Medical and Dental Schools of Guy's and St Thomas' Hospitals on 1 August 1998. As of 2023, the medical school is ranked 5th best in the UK for clinical medicine by U.S. News & World Report, and 10th best worldwide by Times Higher Education.
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy.
The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) is a centre for mental health and neuroscience research, education and training in Europe. It is dedicated to understanding, preventing and treating mental illness, neurological conditions, and other conditions that affect the brain. The IoPPN is a faculty of King's College London, England, and was previously known as the Institute of Psychiatry (IoP).
The Cardiff University School of Medicine is the medical school of Cardiff University and is located in Cardiff, Wales, UK. Founded in 1893 as part of the University College of South Wales and Monmouthshire, it is the oldest of the three medical schools in Wales.
Imperial College School of Medicine (ICSM) is the undergraduate medical school of Imperial College London in England and one of the United Hospitals. It is part of the college's Faculty of Medicine and was formed by the merger of several historic medical schools. Its core campuses are located at South Kensington, St Mary's, Charing Cross, Hammersmith and Chelsea and Westminster. The school ranked 4th in the world for medicine in the 2024 Times Higher Education World University Rankings.
The Royal Postgraduate Medical School (RPMS) was an independent medical school, based primarily at Hammersmith Hospital in west London. In 1988, the school merged with the Institute of Obstetrics & Gynaecology, and in 1997 became part of Imperial College School of Medicine.
Hammersmith Hospital, formerly the Military Orthopaedic Hospital, and later the Special Surgical Hospital, is a major teaching hospital in White City, West London. It is part of Imperial College Healthcare NHS Trust in the London Borough of Hammersmith and Fulham, and is associated with the Imperial College Faculty of Medicine. Confusingly the hospital is not in Hammersmith but is located in White City adjacent to Wormwood Scrubs and East Acton.
The Cambridge Biomedical Campus is the largest centre of medical research and health science in Europe. The site is located at the southern end of Hills Road in Cambridge, England.
Sir David Keith Peters is a retired Welsh physician and academic. He was Regius Professor of Physic at the University of Cambridge from 1987 to 2005, where he was also head of the School of Clinical Medicine.
Hani Gabra PhD FRCPE FRCP is a British oncologist and Professor Emeritus in Medical Oncology at Imperial College London. Prof Gabra is Founder and Chief Scientific Officer of Papyrus Therapeutics, Inc, a preclinical stage Cancer Biotech company registered in Delaware and currently practises as a Consultant Medical Oncologist at Portsmouth Hospitals NHS Trust, acting as Trust Lead Cancer Clinician.
The Faculty of Medicine is the academic centre for medical and clinical research and teaching at Imperial College London. It contains the Imperial College School of Medicine, which is the college's undergraduate medical school.
Elizabeth Simpson is a British biologist. She is the Emeritus Professor of Transplantation Biology at Imperial College London. Simpson is particularly known for her elucidation of the nature of male-associated minor transplantation antigens, and their roles in the generation of immunological tolerance, graft versus host disease, and transplant rejection.
Dame Amanda Gay Fisher is a British cell biologist and Director of the Medical Research Council (MRC) London Institute of Medical Sciences at the Hammersmith Hospital campus of Imperial College London, where she is also a Professor leading the Institute of Clinical Sciences. She has made contributions to multiple areas of cell biology, including determining the function of several genes in HIV and describing the importance of a gene's location within the cell nucleus.
James Scott is a British cardiologist.
Professor Jonathan Samuel Friedland is a British physician and medical researcher who is Deputy Vice-Chancellor and Professor of Infectious Diseases at St George's, University of London.
Miratul Muqit FRSE FMedSci is a British neurologist and a Programme Lead at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRCPPU) in the School of Life Sciences at the University of Dundee. His research focuses on the study of the PINK1 gene, mutations in which are a major cause of Parkinson's disease.
Irene Miguel-Aliaga is a Spanish-British physiologist who is Professor of Genetics and Physiology at Imperial College London. Her research investigates the plasticity of adult organs, and why certain organs change shape in response to environmental changes. She was elected Fellow of the Royal Society in 2022.
Wiebke Arlt is a German endocrinologist. She is Director of the MRC London Institute of Medical Sciences and Head of the Institute of Clinical Sciences at Imperial College London. She is also Honorary Professor at the University of Birmingham. She specialises in adrenal disease and disorders of sex development.
Petra Hajkova is a Professor of Developmental Epigenetics at the Imperial College London. She is also the Deputy Director of the MRC Laboratory of Medical Sciences, where her research group Reprogramming and Chromatin is also hosted.