Martin-Gruber Anastomosis

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A Martin-Gruber anastomosis (MGA) is a connection from the median nerve to the ulnar nerve in the forearm. An anastomosis occurs when two structures that normally are not connected have a connection. In this case the connection is a nerve. The Martin-Gruber anastomosis is most common anastomosis that occurs between these two nerves. [1] This connection carries motor axons which innervate some of the usually ulnar nerve innervated intrinsic muscles.

Contents

This inconstant pattern of connection can serve as explanation for a difficult or challenging differential diagnosis. [2] In one study, [3] the MGA was found in 22.9% of cadaver specimens, while another found the incidence at ~11%. [4] This relatively high incidence demonstrates the necessity for healthcare specialists to factor the MGA into their diagnoses.

Types

There are six types of Martin-Gruber anastomoses.

Clinical Significance

In the setting of proximal ulnar nerve injury, a Martin-Gruber anastomosis can prevent the complete paralysis of the intrinsic muscles of the hand.

Related Research Articles

Median nerve Nerve of the upper limb

The median nerve is a nerve in humans and other animals in the upper limb. It is one of the five main nerves originating from the brachial plexus.

Brachial plexus

The brachial plexus is a network (plexus) of nerves (formed by the anterior rami of the lower four cervical nerves and first thoracic nerve. This plexus extends from the spinal cord, through the cervicoaxillary canal in the neck, over the first rib, and into the armpit. It supplies afferent and efferent nerve fibers to the chest, shoulder, arm, forearm, and hand.

Lumbricals of the hand

The lumbricals are intrinsic muscles of the hand that flex the metacarpophalangeal joints, and extend the interphalangeal joints.

The flexor digitorum profundus is a muscle in the forearm of humans that flexes the fingers. It is considered an extrinsic hand muscle because it acts on the hand while its muscle belly is located in the forearm.

Thenar eminence

The thenar eminence refers to the group of muscles on the palm of the human hand at the base of the thumb. The skin overlying this region is the area stimulated when trying to elicit a palmomental reflex. The word thenar comes from Greek θέναρ (thenar) 'palm of the hand'.

The forearm is the region of the upper limb between the elbow and the wrist. The term forearm is used in anatomy to distinguish it from the arm, a word which is most often used to describe the entire appendage of the upper limb, but which in anatomy, technically, means only the region of the upper arm, whereas the lower "arm" is called the forearm. It is homologous to the region of the leg that lies between the knee and the ankle joints, the crus.

Ulnar nerve

In human anatomy, the ulnar nerve is a nerve that runs near the ulna bone. The ulnar collateral ligament of elbow joint is in relation with the ulnar nerve. The nerve is the largest in the human body unprotected by muscle or bone, so injury is common. This nerve is directly connected to the little finger, and the adjacent half of the ring finger, innervating the palmar aspect of these fingers, including both front and back of the tips, perhaps as far back as the fingernail beds.

Hypoglossal nerve Cranial nerve

The hypoglossal nerve is the twelfth cranial nerve, and innervates all the extrinsic and intrinsic muscles of the tongue, except for the palatoglossus which is innervated by the vagus nerve. It is a nerve with a solely motor function. The nerve arises from the hypoglossal nucleus in the medulla as a number of small rootlets, passes through the hypoglossal canal and down through the neck, and eventually passes up again over the tongue muscles it supplies into the tongue.

Upper limb

The upper limb or upper extremity is the region in a vertebrate animal extending from the deltoid region up to and including the hand, including the arm, axilla and shoulder.

Cervical plexus

The cervical plexus is a plexus of the anterior rami of the first four cervical spinal nerves which arise from C1 to C4 cervical segment in the neck. They are located laterally to the transverse processes between prevertebral muscles from the medial side and vertebral from lateral side. There is anastomosis with accessory nerve, hypoglossal nerve and sympathetic trunk.

Triceps

The triceps, also triceps brachii, is a large muscle on the back of the upper limb of many vertebrates. It consists of 3 parts: the medial, lateral, and long head. It is the muscle principally responsible for extension of the elbow joint.

Recurrent laryngeal nerve Nerve in the human body

The recurrent laryngeal nerve (RLN) is a branch of the vagus nerve that supplies all the intrinsic muscles of the larynx, with the exception of the cricothyroid muscles. There are two recurrent laryngeal nerves, right and left. The right and left nerves are not symmetrical, with the left nerve looping under the aortic arch, and the right nerve looping under the right subclavian artery then traveling upwards. They both travel alongside of the trachea. Additionally, the nerves are one of few nerves that follow a recurrent course, moving in the opposite direction to the nerve they branch from, a fact from which they gain their name.

Brachial plexus injury

A brachial plexus injury (BPI), also known as brachial plexus lesion, is an injury to the brachial plexus, the network of nerves that conducts signals from the spinal cord to the shoulder, arm and hand. These nerves originate in the fifth, sixth, seventh and eighth cervical (C5–C8), and first thoracic (T1) spinal nerves, and innervate the muscles and skin of the chest, shoulder, arm and hand.

Nerve conduction velocity

Nerve conduction velocity (CV) is an important aspect of nerve conduction studies. It is the speed at which an electrochemical impulse propagates down a neural pathway. Conduction velocities are affected by a wide array of factors, including age, sex, and various medical conditions. Studies allow for better diagnoses of various neuropathies, especially demyelinating diseases as these conditions result in reduced or non-existent conduction velocities.

Ulnar nerve entrapment

Ulnar nerve entrapment is a condition where the ulnar nerve becomes physically trapped or pinched, resulting in pain, numbness, or weakness, primarily affecting the little finger and ring finger of the hand. Entrapment may occur at any point from the spine at cervical vertebra C7 to the wrist; the most common point of entrapment is in the elbow. Prevention is mostly through correct posture and avoiding repetitive or constant strain. Treatment is usually conservative, including medication, activity modification and exercise, but may sometimes include surgery. Prognosis is generally good, with mild to moderate symptoms often resolving spontaneously.

Muscles of the hand

The muscles of the hand are the skeletal muscles responsible for the movement of the hand and fingers. The muscles of the hand can be subdivided into two groups: the extrinsic and intrinsic muscle groups. The extrinsic muscle groups are the long flexors and extensors. They are called extrinsic because the muscle belly is located on the forearm. The intrinsic group are the smaller muscles located within the hand itself. The muscles of the hand are innervated by the radial, median, and ulnar nerves from the brachial plexus.

Ulnar claw

An ulnar claw, also known as claw hand, or 'spinster's claw' is a deformity or an abnormal attitude of the hand that develops due to ulnar nerve damage causing paralysis of the lumbricals. A claw hand presents with a hyperextension at the metacarpophalangeal joints and flexion at the proximal and distal interphalangeal joints of the 4th and 5th fingers. The patients with this condition can make a full fist but when they extend their fingers, the hand posture is referred to as claw hand. The ring- and little finger can usually not fully extend at the proximal interphalangeal joint (PIP).

The hand of benediction, also known as benediction sign or preacher's hand, occurs as a result of prolonged compression or injury of the median nerve at the forearm or elbow.

Wartenberg's sign is a neurological sign consisting of involuntary abduction of the fifth (little) finger, caused by unopposed action of the extensor digiti minimi.

Muscles of the thumb

The muscles of the thumb are nine skeletal muscles located in the hand and forearm. The muscles allow for flexion, extension, adduction, abduction and opposition of the thumb. The muscles acting on the thumb can be divided into two groups: The extrinsic hand muscles, with their muscle bellies located in the forearm, and the intrinsic hand muscles, with their muscles bellies located in the hand proper.

References

  1. Erdem HR, Ergun S, Erturk C, Ozel S (June 2002). "Electrophysiological Evaluation of the Incidence of Martin-Gruber Anastomosis in Healthy Subjects". Yonsei Medical Journal. 43 (3): 291–5. doi: 10.3349/ymj.2002.43.3.291 . PMID   12089734.
  2. Unver Dogan, Nadire (March 14, 2009). "The communications between the ulnar and median nerves in upper limb" (PDF). neuroanatomy.org. Retrieved 2012-09-01.
  3. Rodriguez-Niedenführ M, Vazquez T, Parkin I, Logan B, Sañudo JR (March 2002). "Martin-Gruber anastomosis revisited". Clinical Anatomy. 15 (2): 129–34. doi:10.1002/ca.1107. PMID   11877791.
  4. Kaur, et al. (Feb 2016). "Martin–Gruber Anastomosis- A Cadaveric Study in North Indian Population". Journal of Clinical and Diagnostic Research. 10 (2): AC09–AC11. doi:10.7860/JCDR/2016/16447.7247. PMC   4800503 . PMID   27042438.