Electroconvulsive therapy (ECT) or electroshock therapy (EST) is a psychiatric treatment where a generalized seizure is electrically induced to manage refractory mental disorders. Typically, 70 to 120 volts are applied externally to the patient's head, resulting in approximately 800 milliamperes of direct current passing between the electrodes, for a duration of 100 milliseconds to 6 seconds, either from temple to temple or from front to back of one side of the head. However, only about 1% of the electrical current crosses the bony skull into the brain because skull impedance is about 100 times higher than skin impedance.
A Twinkie is an American snack cake, described as "golden sponge cake with a creamy filling". It was formerly made and distributed by Hostess Brands. The brand is currently owned by Hostess Brands, Inc., itself currently owned by The J.M. Smucker Company and having been formerly owned by private equity firms Apollo Global Management and C. Dean Metropoulos and Company as the second incarnation of Hostess Brands. During bankruptcy proceedings, Twinkie production was suspended on November 15, 2012, and resumed after an absence of a few months from American store shelves, becoming available again nationwide on July 15, 2013.
In criminal law, diminished responsibility is a potential defense by excuse by which defendants argue that although they broke the law, they should not be held fully criminally liable for doing so, as their mental functions were "diminished" or impaired.
The abuse defense is a criminal law defense in which the defendant argues that a prior history of abuse justifies violent retaliation. While the term most often refers to instances of child abuse or sexual assault, it also refers more generally to any attempt by the defense to use a syndrome or societal condition to deflect responsibility away from the defendant. Sometimes the concept is referred to as the abuse excuse, in particular by the critics of the idea that guilty people may use past victimization to diminish the responsibility for their crimes.
"Twinkie defense" is a derisive label for an improbable legal defense. It is not a recognized legal defense in jurisprudence, but a catch-all term coined by reporters during their coverage of the trial of defendant Dan White for the murders of San Francisco city Supervisor Harvey Milk and Mayor George Moscone. White's defense was that he suffered diminished capacity as a result of his depression, a symptom of which was a change in diet from healthy food to Twinkies and other sugary foods. Contrary to common belief, White's attorneys did not argue that the Twinkies were the cause of White's actions, but that their consumption was symptomatic of his underlying depression. The product itself was only mentioned in passing during the trial. White was convicted of voluntary manslaughter rather than first-degree murder, and served five years in prison.
Daniel James White was an American politician who assassinated George Moscone, the mayor of San Francisco, and Harvey Milk, a member of the San Francisco Board of Supervisors, inside City Hall on November 27, 1978. White was convicted of manslaughter for the deaths of Milk and Moscone and served five years of a seven-year prison sentence. Less than two years after his release, he returned to San Francisco and later committed suicide.
George Richard Moscone was an attorney and Democratic politician who was the 37th mayor of San Francisco, California from January 1976 until his assassination in November 1978. He was known as "The People's Mayor," who opened up City Hall and its commissions to reflect the diversity of San Francisco, appointing African Americans, Asian Americans, and gay people. Moscone served in the California State Senate from 1967 until becoming mayor. In the Senate, he served as majority leader. Moscone is remembered for being an advocate of civil progressivism.
The White Night riots were a series of violent events sparked by an announcement of a lenient sentencing of Dan White for the assassinations of George Moscone, the mayor of San Francisco, and of Harvey Milk, a member of the city's Board of Supervisors who was one of the first openly gay elected officials in the United States. The events took place on the night of May 21, 1979, in San Francisco. Earlier that day White had been convicted of voluntary manslaughter, the lightest possible conviction for his actions. The lesser conviction outraged the city's gay community, setting off the most violent reaction by gay Americans since the 1969 Stonewall riots in New York City.
Elizabeth F. Loftus is an American psychologist who is best known in relation to the misinformation effect, false memory and criticism of recovered memory therapies.
Forensic psychiatry is a subspeciality of psychiatry and is related to criminology. It encompasses the interface between law and psychiatry. According to the American Academy of Psychiatry and the Law, it is defined as "a subspecialty of psychiatry in which scientific and clinical expertise is applied in legal contexts involving civil, criminal, correctional, regulatory, or legislative matters, and in specialized clinical consultations in areas such as risk assessment or employment." A forensic psychiatrist provides services – such as determination of competency to stand trial – to a court of law to facilitate the adjudicative process and provide treatment, such as medications and psychotherapy, to criminals.
Park Elliot Dietz is a forensic psychiatrist who has consulted or testified in many of the highest-profile US criminal cases, including those of spousal killer Betty Broderick, mass murderer Jared Lee Loughner, and serial killers Joel Rifkin, Arthur Shawcross, Jeffrey Dahmer, Ted Kaczynski, Richard Kuklinski, the D.C. sniper attacks, and William Bonin.
Martin Theodore Orne was a professor of psychiatry and psychology at the University of Pennsylvania. Orne is best known for his pioneering research into demand characteristics, illustrating the weakness of informing participants that they are taking part in a psychology experiment and yet expecting them to act normally. He was well known as a researcher in the field of hypnosis and is also noted for his involvement with the poet Anne Sexton, and with the trials of Patty Hearst and Kenneth Bianchi.
On November 27, 1978, George Moscone, the mayor of San Francisco, and Harvey Milk, a member of the San Francisco Board of Supervisors, were shot and killed inside City Hall by former Supervisor Dan White. On the morning of that day, Moscone intended to announce that the Supervisor position from which White had previously resigned would be given to someone else. White, angered, entered City Hall before the scheduled announcement and first shot Moscone in the Mayor's office, then Milk in White's former office space, before escaping the building. Board of Supervisors President Dianne Feinstein first announced Moscone and Milk's deaths to the media, and because of Moscone's death, succeeded him as acting mayor.
Execution of Justice is an ensemble play by Emily Mann chronicling the case of Dan White, who assassinated San Francisco mayor George Moscone and openly gay city supervisor Harvey Milk in November 1978. The play was originally commissioned by the Eureka Theatre Company, but premiered at Arena Stage on May 10, 1985.
Geriatric psychiatry, also known as geropsychiatry, psychogeriatrics or psychiatry of old age, is a branch of medicine and a subspecialty of psychiatry dealing with the study, prevention, and treatment of neurodegenerative, cognitive impairment, and mental disorders in people of old age. Geriatric psychiatry as a subspecialty has significant overlap with the specialties of geriatric medicine, behavioural neurology, neuropsychiatry, neurology, and general psychiatry. Geriatric psychiatry has become an official subspecialty of psychiatry with a defined curriculum of study and core competencies.
Patricia Rosarie Casey is an Irish psychiatrist, academic, journalist and conservative commentator on social issues. She is Professor of Psychiatry at University College Dublin and consultant psychiatrist at the Mater Misericordiae University Hospital, Dublin. She is known for her regular column with the Irish Independent newspaper, and her conservative views on a variety of social issues.
Dennis S. Charney is an American biological psychiatrist and researcher, with expertise in the neurobiology and treatment of mood and anxiety disorders. He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular Biology for the Clinician, as well as the author of over 600 original papers and chapters. In 2022, he was listed #52 on Research.com's "Top Medicine Scientists in the United States," with an h-index of 194 with 146,109 citations across 651 publications. Charney is known for demonstrating that ketamine is effective for treating depression. Ketamine's use as a rapidly-acting anti-depressant is recognized as a breakthrough treatment in mental illness.
Paul Rodney McHugh is an American psychiatrist, researcher, and educator. He is currently the University Distinguished Service Professor of Psychiatry at the Johns Hopkins University School of Medicine and the author, co-author, or editor of seven books in his field.
The Emperor's New Drugs – Exploding the Antidepressant Myth is a 2009 book by Irving Kirsch, arguing that the chemical imbalance theory of depression is wrong and that antidepressants have little or no direct effect on depression but, because of their common or serious side-effects, they are powerful active placebos.
Study 329 was a clinical trial which was conducted in North America from 1994 to 1998 to study the efficacy of paroxetine, an SSRI anti-depressant, in treating 12- to 18-year-olds diagnosed with major depressive disorder. Led by Martin Keller, then professor of psychiatry at Brown University, and funded by the British pharmaceutical company SmithKline Beecham—known since 2000 as GlaxoSmithKline (GSK)—the study compared paroxetine with imipramine, a tricyclic antidepressant, and placebo. SmithKline Beecham had released paroxetine in 1991, marketing it as Paxil in North America and Seroxat in the UK. The drug attracted sales of $11.7 billion in the United States alone from 1997 to 2006, including $2.12 billion in 2002, the year before it lost its patent.
