Michael R. Lerner

Dr.
Michael Rush Lerner
Dr. Michael Rush Lerner
Born	Portland, Oregon, United States
Nationality	American
Citizenship	United States
Occupation	Dermatologist
Known for	Discovery of snRNP; STEP bioassay; research on Smoothened as GPCR
	Medical career
Profession	Physician
Field	Dermatology; Molecular biology
Sub-specialties	Dermatology; Molecular biology; GPCR research
Research	snRNP; GPCR bioassays

Last updated October 28, 2025

Michael Rush Lerner is a dermatologist in San Diego, California.^[1]

Lerner was born in Portland, Oregon.^{[ citation needed ]}

He discovered snRNPs with Joan A. Steitz,^[2] STEP (with Paul Lombroso), created the melanophore based GPCR bioassay and demonstrated that Smoothened is a GPCR.^[2]

References

↑ "Dr. Michael Lerner, Dermatologist in San Diego, CA | US News Doctors". health.usnews.com. 2015. Retrieved 22 November 2015.
1 2 Lerner MR, Steitz JA (November 1979). "Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus". Proc. Natl. Acad. Sci. U.S.A. 76 (11): 5495–9. Bibcode:1979PNAS...76.5495R. doi: 10.1073/pnas.76.11.5495 . PMC 411675 . PMID 316537.

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[1] "Dr. Michael Lerner, Dermatologist in San Diego, CA | US News Doctors". health.usnews.com. 2015. Retrieved 22 November 2015.

[pmid_316537-2] 1 2 Lerner MR, Steitz JA (November 1979). "Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus". Proc. Natl. Acad. Sci. U.S.A. 76 (11): 5495–9. Bibcode:1979PNAS...76.5495R. doi: 10.1073/pnas.76.11.5495 . PMC 411675 . PMID 316537.

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