The Minnesota Center for Twin and Family Research (MCTFR) is a series of behavioral genetic longitudinal studies of families with twin or adoptive offspring conducted by researchers at the University of Minnesota. [1] It seeks to identify and characterize the genetic and environmental influences on the development of psychological traits.
Principal investigators include Matt McGue, William Iacono, and Kevin Haroian.
The primary cohorts of participants include the Minnesota Twin Family Study, Sibling Interaction and Behavior Study, Minnesota Twin Registry, and a variety of other cohorts of participants. [1]
MTFS is a twin study established in June 1989 with 1300 same-gendered twin pairs age 11 or 17, with an additional cohort of 500 such pairs recruited around 2004. Twins were born between 1972 and 2000. [1] All twins born in Minnesota at that time were eligible to participate using birth registry data. Both identical and fraternal twins share certain aspects of their environment. This allows researchers to estimate the relative impact of environmental and genetic influences on phenotypes. The focus of the MTFS is on behavioral phenotypes, such as academic outcomes, cognitive abilities, personality, and interests; family and social relationships; mental and physical health; physiological measurements. The assessment wave structure and protocol are similar to the Sibling Interaction and Behavior Study (below), allowing the use of complementary twin and adoption designs to address behavioral genetic questions.
The Minnesota Twin Registry was established in 1983. [2] Its original goal was to establish a registry of all twins born in Minnesota from 1936 to 1955 to be used for psychological research. Recently, it has added twins born between 1961 and 1964. It primarily conducts personality and interests tests with its 8,000+ twin pairs and family members via mail. From this project, it was able to confirm that twins and their families are representative of the population and that a poll of their opinions would be more accurate than polls in the newspaper.
The Sibling Interaction and Behavior Study (SIBS) is a study of >600 adoptive and non-adoptive families. [1] The adoption study design allows one to disentangle the environmental and genetic influences on a phenotype, including psychological phenotypes. The assessment wave structure and protocol are similar to the Minnesota Twin Family Study, allowing the use of complementary study designs to answer a given question.
The Minnesota Study of Twins Reared Apart was a twin study conducted at the University of Minnesota, independent of the Minnesota Center for Twin and Family Research. In 1979, Thomas J. Bouchard began to study twins who were separated at birth and reared in different families. He found that an identical twin reared away from his or her co-twin seems to have about an equal chance of being similar to the co-twin in terms of personality, interests, and attitudes as one who has been reared with his or her co-twin. [3] Bouchard has said that these two twins happened to be unusually alike, while most twins show more differences: [4]
There probably are genetic influences on almost all facets of human behavior, but the emphasis on the idiosyncratic characteristics is misleading. On average, identical twins raised separately are about 50 percent similar – and that defeats the widespread belief that identical twins are carbon copies. Obviously, they are not. Each is a unique individual in his or her own right.
Psychologists now refer to studies such as this as an Adoption Strategy. [5] [6] Partial funding for the study was obtained through a research grant from the Pioneer Fund. [7]
Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents. Legal adoptions permanently transfer all rights and responsibilities, along with filiation, from the biological parents to the adoptive parents.
Nature versus nurture is a long-standing debate in biology and society about the relative influence on human beings of their genetic inheritance (nature) and the environmental conditions of their development (nurture). The alliterative expression "nature and nurture" in English has been in use since at least the Elizabethan period and goes back to medieval French. The complementary combination of the two concepts is an ancient concept. Nature is what people think of as pre-wiring and is influenced by genetic inheritance and other biological factors. Nurture is generally taken as the influence of external factors after conception e.g. the product of exposure, experience and learning on an individual.
Twin studies are studies conducted on identical or fraternal twins. They aim to reveal the importance of environmental and genetic influences for traits, phenotypes, and disorders. Twin research is considered a key tool in behavioral genetics and in related fields, from biology to psychology. Twin studies are part of the broader methodology used in behavior genetics, which uses all data that are genetically informative – siblings studies, adoption studies, pedigree, etc. These studies have been used to track traits ranging from personal behavior to the presentation of severe mental illnesses such as schizophrenia.
Human behaviour genetics is an interdisciplinary subfield of behaviour genetics that studies the role of genetic and environmental influences on human behaviour. Classically, human behavioural geneticists have studied the inheritance of behavioural traits. The field was originally focused on determining the importance of genetic influences on human behaviour. It has evolved to address more complex questions such as: how important are genetic and/or environmental influences on various human behavioural traits; to what extent do the same genetic and/or environmental influences impact the overlap between human behavioural traits; how do genetic and/or environmental influences on behaviour change across development; and what environmental factors moderate the importance of genetic effects on human behaviour. The field is interdisciplinary, and draws from genetics, psychology, and statistics. Most recently, the field has moved into the area of statistical genetics, with many behavioural geneticists also involved in efforts to identify the specific genes involved in human behaviour, and to understand how the effects associated with these genes changes across time, and in conjunction with the environment.
Thomas J. Bouchard Jr. is an American psychologist known for his behavioral genetics studies of twins raised apart. He is professor emeritus of psychology and director of the Minnesota Center for Twin and Adoption Research at the University of Minnesota. Bouchard received his PhD from the University of California, Berkeley, in 1966.
Richard D. Arvey is an American psychology professor.
In psychology, a trait is called emergenic if it is the result of a specific combination of several interacting genes. Emergenic traits will not run in families, but identical twins will share them. Traits such as "leadership", "genius" or certain mental illnesses may be emergenic. Although one may expect epigenetics to play a significant role in the phenotypic manifestation of twins reared apart, the concordance displayed between them can be attributed to emergenesis.
Research on the heritability of IQ inquires into the degree of variation in IQ within a population that is due to genetic variation between individuals in that population. There has been significant controversy in the academic community about the heritability of IQ since research on the issue began in the late nineteenth century. Intelligence in the normal range is a polygenic trait, meaning that it is influenced by more than one gene, and in the case of intelligence at least 500 genes. Further, explaining the similarity in IQ of closely related persons requires careful study because environmental factors may be correlated with genetic factors.
Personality development encompasses the dynamic construction and deconstruction of integrative characteristics that distinguish an individual in terms of interpersonal behavioral traits. Personality development is ever-changing and subject to contextual factors and life-altering experiences. Personality development is also dimensional in description and subjective in nature. That is, personality development can be seen as a continuum varying in degrees of intensity and change. It is subjective in nature because its conceptualization is rooted in social norms of expected behavior, self-expression, and personal growth. The dominant viewpoint in personality psychology indicates that personality emerges early and continues to develop across one's lifespan. Adult personality traits are believed to have a basis in infant temperament, meaning that individual differences in disposition and behavior appear early in life, potentially before language of conscious self-representation develop. The Five Factor Model of personality maps onto the dimensions of childhood temperament. This suggests that individual differences in levels of the corresponding personality traits are present from young ages.
The field of psychology has been greatly influenced by the study of genetics. Decades of research have demonstrated that both genetic and environmental factors play a role in a variety of behaviors in humans and animals. The genetic basis of aggression, however, remains poorly understood. Aggression is a multi-dimensional concept, but it can be generally defined as behavior that inflicts pain or harm on another.
Nancy L. Segal is an American evolutionary psychologist and behavioral geneticist, specializing in the study of twins. She is the Professor of Developmental Psychology and Director of the Twin Studies Center, at California State University, Fullerton. Segal was a recipient of the 2005 James Shields Award for Lifetime Contributions to Twin Research from the Behavior Genetics Association and International Society for Twin Studies.
Gene–environment correlation is said to occur when exposure to environmental conditions depends on an individual's genotype.
Irving Isadore Gottesman was an American professor of psychology who devoted most of his career to the study of the genetics of schizophrenia. He wrote 17 books and more than 290 other publications, mostly on schizophrenia and behavioral genetics, and created the first academic program on behavioral genetics in the United States. He won awards such as the Hofheimer Prize for Research, the highest award from the American Psychiatric Association for psychiatric research. Lastly, Gottesman was a professor in the psychology department at the University of Minnesota, where he received his Ph.D.
Behavioural genetics, also referred to as behaviour genetics, is a field of scientific research that uses genetic methods to investigate the nature and origins of individual differences in behaviour. While the name "behavioural genetics" connotes a focus on genetic influences, the field broadly investigates the extent to which genetic and environmental factors influence individual differences, and the development of research designs that can remove the confounding of genes and environment. Behavioural genetics was founded as a scientific discipline by Francis Galton in the late 19th century, only to be discredited through association with eugenics movements before and during World War II. In the latter half of the 20th century, the field saw renewed prominence with research on inheritance of behaviour and mental illness in humans, as well as research on genetically informative model organisms through selective breeding and crosses. In the late 20th and early 21st centuries, technological advances in molecular genetics made it possible to measure and modify the genome directly. This led to major advances in model organism research and in human studies, leading to new scientific discoveries.
A twin registry is a database of information about both identical twins and fraternal twins, which is often maintained by an academic institution, such as a university, or by other research institutions.
Adoption studies typically compare pairs of persons, e.g., adopted child and adoptive mother or adopted child and biological mother, to assess genetic and environmental influences on behavior. These studies are one of the classic research methods of behavioral genetics. The method is used alongside twin studies to identify the roles of genetics and environmental variables that impact intelligence, and behavioral disorders.
Robert Frank Krueger is Hathaway Distinguished Professor of Clinical Psychology and Distinguished McKnight University Professor in the Department of Psychology at the University of Minnesota. He is known for his research on personality psychology, clinical psychology, quantitative psychology, developmental psychology, personality disorders, behavioral genetics, and psychopathology. He is the co-editor-in-chief of the Journal of Personality Disorders.
William George Iacono is an American psychologist known for his research in behavior genetics. He uses methodologies such as twin and adoption studies, to study the development of common mental disorders and substance abuse.
Wendy Johnson is an American differential psychologist and professor of psychology at the University of Edinburgh. She holds the chair in Differential Development in the Department of Psychology and Centre for Cognitive Ageing and Cognitive Epidemiology at the University of Edinburgh.
The Swedish Twin Registry is a twin registry based at the Karolinska Institutet in Stockholm, Sweden. Originally established in the 1960s, it is the largest twin registry in the world. It is widely used for medical research, with about thirty active research projects using data from the study as of 2019. As of 2012, it contained a total of 194,000 twins, 75,000 of whom were of a known zygosity. In principle, it contains records of every twin born in Sweden since 1886.