This is a list of all NFL players who had outstanding performances throughout the 1920s and have been compiled onto this fantasy group. The team was selected by voters of the Pro Football Hall of Fame retroactively in 1969 to mark the league's 50th anniversary.
| Position | Player | Team(s) | Years | Hall of Fame Class |
|---|---|---|---|---|
| Quarterback | Jimmy Conzelman | Decatur Staleys | 1920 | 1964 |
| Rock Island Independents | 1921–1922 | |||
| Milwaukee Badgers | 1922–1924 | |||
| Detroit Panthers | 1925–1926 | |||
| Providence Steam Roller | 1927–1930 | |||
| Chicago Cardinals | 1940–1942, 1946–1948 | |||
| John "Paddy" Driscoll | Hammond Pros | 1919 | 1965 | |
| Decatur Staleys/Chicago Bears | 1920, 1926–1929 | |||
| Chicago Cardinals | 1920–1925 | |||
| Halfback | Harold “Red” Grange | Chicago Bears | 1925, 1929–1934 | 1963 |
| New York Yankees (AFL) | 1926 | |||
| New York Yankees | 1927 | |||
| Joe Guyon | Canton Bulldogs | 1919–1920 | 1966 | |
| Cleveland Indians | 1921 | |||
| Oorang Indians | 1922–1923 | |||
| Rock Island Independents | 1924 | |||
| Kansas City Cowboys | 1924–1925 | |||
| New York Giants | 1927 | |||
| Earl “Curly” Lambeau | Green Bay Packers | 1919–1949 | 1963 | |
| Chicago Cardinals | 1950–1951 | |||
| Washington Redskins | 1952–1953 | |||
| Jim Thorpe | Canton Bulldogs | 1915–1917, 1919–1920, 1926 | 1963 | |
| Cleveland Indians | 1921 | |||
| Oorang Indians | 1922–1923 | |||
| Rock Island Independents | 1924 | |||
| New York Giants | 1925 | |||
| Chicago Cardinals | 1928 | |||
| Fullback | Ernie Nevers | Duluth Eskimos | 1926–1927 | 1963 |
| Chicago Cardinals | 1929–1931 | |||
| End | Guy Chamberlin | Canton Bulldogs | 1919, 1922–1923 | 1965 |
| Decatur/Chicago Staleys | 1920–1921 | |||
| Cleveland Bulldogs | 1924 | |||
| Frankford Yellow Jackets | 1925–1926 | |||
| Chicago Cardinals | 1927–1928 | |||
| Lavern Dilweg | Milwaukee Badgers | 1926 | Not Inducted | |
| Green Bay Packers | 1927–1934 | |||
| George Halas | Decatur/Chicago Staleys-Chicago Bears | 1920–1983 | 1963 | |
| Tackle | Ed Healey | Rock Island Independents | 1920–1922 | 1964 |
| Chicago Bears | 1922–1927 | |||
| Wilbur “Pete” Henry | Canton Bulldogs | 1920–1923, 1925–1926 | 1963 | |
| New York Giants | 1927 | |||
| Pottsville Maroons | 1927–1928 | |||
| Cal Hubbard | New York Giants | 1927–1928, 1936 | 1963 | |
| Green Bay Packers | 1929–1933, 1935 | |||
| Pittsburgh Pirates | 1934 | |||
| Steve Owen | Kansas City Cowboys | 1924–1925 | 1966 | |
| Cleveland Bulldogs | 1925 | |||
| New York Giants | 1926–1953 | |||
| Guard | Heartley "Hunk" Anderson | Chicago Bears | 1922, 1923–1925 | Not Inducted |
| Cleveland Bulldogs | 1923 | |||
| Walt Kiesling | Duluth Eskimos | 1926–1927 | 1966 | |
| Pottsville Maroons | 1926 | |||
| Chicago Cardinals | 1929–1933 | |||
| Chicago Bears | 1934 | |||
| Green Bay Packers | 1935–1936 | |||
| Pittsburgh Pirates | 1937–1939 | |||
| Mike Michalske | New York Yankees (AFL) | 1926 | 1964 | |
| New York Yankees | 1927–1928 | |||
| Green Bay Packers | 1929–1935, 1937 | |||
| Center | George Trafton | Decatur/Chicago Staleys Chicago Bears | 1920–1921 1922–1932 | 1964 |