Nicki Packer

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Nicki Packer (also known as Nicolle Packer) FRSC is an Australian college professor and researcher. She currently serves as a distinguished professor of glycoproteomics in the School of Natural Sciences at Macquarie University and principal research leader at Griffith University's Institute for Glycomics. Packer is a Fellow of the Royal Society of Chemistry and in 2021 received the Distinguished Achievement in Proteomic Sciences Award from the Human Proteome Organization. [1] Her research focuses on biological functional of glycoconjugates by linking glycomics with proteomics and bioinformatics.

Contents

Career

Packer's research focuses on glycoconjugates, a topic at the intersection of chemistry and biological sciences which aims to identify and study the function of the collection of glycoproteins, glycolipids and proteoglycans in cells and on cell surfaces. Her research program examines the structure, function and role of glycans in cancer and microbial infections, as well as their application in therapeutics. [2]

Packer started her research career with a PhD from the University of Sydney in 1978. [3] In 1999 she co-founded Proteome Systems Limited, an Australian biotech company which developed glycoanalytical technology and informatics tools. Packer became a professor at Macquarie University in 2007 and in 2017 became a distinguished professor and also became the principal research leader at the Institute for Glycomics at Griffith University. [2]

Packer is academic lead of the Australian Proteome Analysis Facility at Macquarie University. [4] In 2017 Packer co-founded the Human Glycoproteomics Initiative (HGI) as part of the Human Proteome Organisation (HUPO) [5] and the Australian Glycoscience Society Glyco@Oz in 2019 to connect Australian glycoscientists. [6] She was deputy director of Macquarie University's Biomolecular Discovery Research Centre. [7]

Packer has had multiple roles in ARC-funded research centres, including:

Awards and prizes

Packer's awards and prizes include:

Media

Packer's glycoproteomics work has been reported in The Toronto Star, [18] The Age, [19] BioSpectrum Asia [20] and by the Royal Society of Chemistry. [21] Her work with The Australian biotechnology company Proteome Systems was reported in the New York Times. [22] Packer's work on the role of sugars in a wide range of human diseases was featured in the Macquarie University publication, The Lighthouse. [23]

Publications

Packer has published over 250 journal articles and book chapters, has over 12,000 citations and has an h-index of 61 (as at April 2022). [24] Packer is an editor of the textbook Essentials of Glycobiology. [25]

Selected journal articles

References

  1. 1 2 "HUPO - HUPO Awards - 2021 Recipients". hupo.org. Retrieved 7 April 2022.
  2. 1 2 "Nicki Packer". Macquarie University. Retrieved 11 April 2022.
  3. ↑ Packer, Nicolle (1978). "Morphogenesis and lipids of the yeast Trigonopsis variabilis". University of Sydney. Retrieved 14 April 2022.
  4. ↑ Administration. "Staff Profiles". Macquarie University. Retrieved 7 April 2022.
  5. ↑ "HUPO - Human Glycoproteomics Initiative". www.hupo.org. Retrieved 11 April 2022.
  6. ↑ "About Us". Glyco@Oz. 19 January 2020. Retrieved 7 April 2022.
  7. ↑ Administration. "Our people". Macquarie University. Retrieved 7 April 2022.
  8. ↑ "Distinguished Prof Nicolle Packer". Faab Australia. 2 February 2022. Retrieved 7 April 2022.
  9. ↑ "About Us". ARC Centre of Excellence in Synthetic Biology. Retrieved 7 April 2022.
  10. ↑ "Prof Nicki Packer – ARC Centre for Innovations in Peptide and Protein Science" . Retrieved 7 April 2022.
  11. ↑ "Our People". CNBP. Retrieved 7 April 2022.
  12. ↑ "Grant - Grants Data Portal". dataportal.arc.gov.au. Retrieved 11 April 2022.
  13. ↑ "APS Awards". Australasian Proteomics Society. Retrieved 9 October 2022.
  14. ↑ "New Distinguished Professors announced | This Week At Macquarie University" . Retrieved 7 April 2022.
  15. 1 2 Administration. "News and events". Macquarie University. Retrieved 7 April 2022.
  16. ↑ "Past MCP ASBMB Award Winners". www.glycobiology.org. Retrieved 7 April 2022.
  17. ↑ "A celebration of world-leading research with world-changing impact | This Week At Macquarie University" . Retrieved 7 April 2022.
  18. ↑ "A week's worth of science news". The Toronto Star. 29 April 2007. ISSN   0319-0781 . Retrieved 7 April 2022.
  19. ↑ "Think tank". The Age. 11 July 2005. Retrieved 7 April 2022.
  20. ↑ "Patrys' cancer diagnostic gets Australian govt grant". www.biospectrumasia.com. Retrieved 7 April 2022.
  21. ↑ "Editor Viewpoints: Unlocking the cell's sugary secrets". Royal Society of Chemistry. 26 June 2020. Retrieved 7 April 2022.
  22. ↑ Rosenthal, Elisabeth (5 September 2005). "Antidoping Agency Seeks Test for EPO That Is Definitive". The New York Times. ISSN   0362-4331 . Retrieved 7 April 2022.
  23. ↑ Molloy, Fran (22 March 2018). "Sugar is involved in almost all human diseases, new research". The Lighthouse. Retrieved 7 April 2022.
  24. ↑ "Scopus preview - Packer, Nicolle - Author details - Scopus". www.scopus.com. Retrieved 14 April 2022.
  25. ↑ Varki, A.; Cummings, R. D.; Esko, J. D.; Stanley, P.; Hart, G. W.; Aebi, M.; Mohnen, D.; Kinoshita, T.; Packer, N. H.; Prestegard, J. H.; Schnaar, R. L.; Seeberger, P. H. (2022). Varki, Ajit; Cummings, Richard D.; Esko, Jeffrey D.; Stanley, Pamela; Hart, Gerald W.; Aebi, Markus; Mohnen, Debra; Kinoshita, Taroh; Packer, Nicolle H. (eds.). Essentials of Glycobiology (4th ed.). Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press. doi:10.1101/9781621824213 (inactive 1 November 2024). ISBN   978-1-62182-421-3. PMID   35536922.{{cite book}}: CS1 maint: DOI inactive as of November 2024 (link)
  26. ↑ Oliveira, Tiago; Thaysen-Andersen, Morten; Packer, Nicolle H.; Kolarich, Daniel (27 August 2021). "The Hitchhiker's guide to glycoproteomics". Biochemical Society Transactions. 49 (4): 1643–1662. doi:10.1042/BST20200879. ISSN   0300-5127. PMC   8421054 . PMID   34282822.
  27. ↑ Varki, Ajit; Cummings, Richard D; Aebi, Markus; Packer, Nicole H; Seeberger, Peter H; Esko, Jeffrey D; Stanley, Pamela; Hart, Gerald; Darvill, Alan; Kinoshita, Taroh; Prestegard, James J (December 2015). "Symbol Nomenclature for Graphical Representations of Glycans". Glycobiology. 25 (12): 1323–1324. doi:10.1093/glycob/cwv091. ISSN   0959-6658. PMC   4643639 . PMID   26543186.
  28. ↑ Jensen, Pia H; Karlsson, Niclas G; Kolarich, Daniel; Packer, Nicolle H (July 2012). "Structural analysis of N- and O-glycans released from glycoproteins" . Nature Protocols. 7 (7): 1299–1310. doi:10.1038/nprot.2012.063. ISSN   1754-2189. PMID   22678433. S2CID   20516889.
  29. ↑ Cooper, Catherine A.; Gasteiger, Elisabeth; Packer, Nicolle H. (February 2001). <340::aid-prot340>3.0.co;2-b "GlycoMod - A software tool for determining glycosylation compositions from mass spectrometric data" . Proteomics. 1 (2): 340–349. doi:10.1002/1615-9861(200102)1:2<340::aid-prot340>3.0.co;2-b. ISSN   1615-9853. PMID   11680880. S2CID   8712883.
  30. ↑ Thaysen-Andersen, Morten; Kolarich, Daniel; Packer, Nicolle H. (2021). "Glycomics & Glycoproteomics: From Analytics to Function". Molecular Omics. 17 (1): 8–10. doi: 10.1039/D0MO90019B . hdl: 10072/400201 . ISSN   2515-4184. PMID   33295916. S2CID   228078995.
  31. ↑ York, William S; Mazumder, Raja; Ranzinger, Rene; Edwards, Nathan; Kahsay, Robel; Aoki-Kinoshita, Kiyoko F; Campbell, Matthew P; Cummings, Richard D; Feizi, Ten; Martin, Maria; Natale, Darren A (28 January 2020). "GlyGen: Computational and Informatics Resources for Glycoscience". Glycobiology. 30 (2): 72–73. doi:10.1093/glycob/cwz080. ISSN   1460-2423. PMC   7335483 . PMID   31616925.
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