Nuclear moulding

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Micrograph of a small cell carcinoma showing cells with nuclear moulding. FNA specimen. Field stain. Small cell lung cancer - cytology.jpg
Micrograph of a small cell carcinoma showing cells with nuclear moulding. FNA specimen. Field stain.

In histo pathology, nuclear moulding, also nuclear molding, is conformity of adjacent cell nuclei to one another. [1]

It is a feature of small cell carcinomas and particularly useful for differentiation of small cell and non-small cell carcinomas, i.e. adenocarcinoma and squamous carcinoma. [2]

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References

  1. https://web.archive.org/web/20160304055452/http://www.vet.ohio-state.edu/assets/courses/vm618/gloss/glossary.html. Archived from the original on 2016-03-04. Retrieved 2010-02-20.{{cite web}}: Missing or empty |title= (help)
  2. Cakir, E.; Demirag, F.; Aydin, M. (Feb 2010). "Cytopathologic differential diagnosis of small cell carcinoma and poorly differentiated non-small cell carcinoma in bronchial lavage specimens using a regression analysis". APMIS. 118 (2): 150–5. doi:10.1111/j.1600-0463.2009.02575.x. PMID   20132179. S2CID   29966888.