Pegylated interferon

Last updated

Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: [1]

In these formulations, Polyethylene glycol (PEG) is added to make interferon last longer in the body. [3] They are used to treat both hepatitis B, [4] hepatitis C [1] and multiple sclerosis. [2]

Pegylated interferon is contraindicated in patients with hyperbilirubinaemia.[ citation needed ]

References

  1. 1 2 Jirillo, Emilio, ed. (2008). Hepatitis C virus disease : immunobiology and clinical applications ([Online-Ausg.] ed.). New York: Springer. p. 237. ISBN   978-0-387-71375-5.
  2. 1 2 Kieseier BC, Calabresi PA.; Calabresi (2012). "PEGylation of Interferon-β-1a: A Promising Strategy in Multiple Sclerosis". CNS Drugs. 26 (3): 205–14. doi:10.2165/11596970-000000000-00000. PMID   22201341. S2CID   34290702. Archived from the original on 2013-01-01.
  3. ↑ Martin P (February 15, 2001). "Hepatology Focus: Update on Hepatitis C Treatment: Pegylated Interferon". medscape.
  4. ↑ Dancygier H, Allescher HD (2010). Clinical Hepatology. [S.l.]: Springer Berlin Heidelberg. p. 765. ISBN   978-3-642-04509-7.


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.