Elisa Longo Borghini is an Italian professional road cyclist, who rides for UCI Women's WorldTeam Lidl–Trek.
Alfredo Martini was an Italian cyclist and coach from Sesto Fiorentino, north of Florence. Professional from 1941 to 1957, he won a stage in the 1950 Giro d'Italia and was later the coach of the Italian national team. He also rode in the 1949 Tour de France. In 2021, in honour of Martini's 100th birthday, the one-day race Per sempre Alfredo was first held; the race finishes in Martini's home town of Sesto Fiorentino.
Dion Smith is a New Zealand cyclist, who currently rides for UCI WorldTeam Intermarché–Wanty.
Rémy Mertz is a Belgian former cyclist, who competed as a professional from 2014 to 2023. He was named in the startlist for the 2017 Vuelta a España.
Nicola Conci is an Italian cyclist, who rides for UCI WorldTeam Alpecin–Deceuninck.
Matteo Moschetti is an Italian cyclist, who currently rides for UCI ProTeam Q36.5 Pro Cycling Team.
Alessandro Fedeli is an Italian former cyclist, who competed as a professional from 2018 to 2023.
Giovanni Lonardi is an Italian cyclist, who currently rides for UCI ProTeam Team Polti Kometa. In May 2019, he was named in the startlist for the 2019 Giro d'Italia.
Andrea Garosio is an Italian cyclist, who currently rides for UCI ProTeam Team Polti Kometa. In May 2019, he was named in the startlist for the 2019 Giro d'Italia.
Natnael Tesfatsion Ocbit is an Eritrean cyclist, who currently rides for UCI WorldTeam Lidl–Trek.
Luc Wirtgen is a Luxembourgish cyclist, who currently rides for UCI ProTeam Tudor Pro Cycling Team. His brother Tom Wirtgen is also a professional cyclist.
Kevin Colleoni is an Italian cyclist, who currently rides for UCI WorldTeam Intermarché–Wanty.
The 2021 Trek–Segafredo season was the team's 11th season overall, of which all of them have been at UCI WorldTeam level, and the 6th season under the current name.
The 2021 Per sempre Alfredo was the 1st edition of the Per sempre Alfredo road cycling one day race, which was held on 21 March 2021, starting in the city of Florence and finishing in Alfredo Martini's home town of Sesto Fiorentino.
Marius Mayrhofer is a German cyclist, who currently rides for UCI ProTeam Tudor Pro Cycling Team.
Kim Heiduk is a German cyclist, who currently rides for UCI WorldTeam Ineos Grenadiers.
Luca Colnaghi is an Italian racing cyclist, who currently rides for UCI ProTeam VF Group–Bardiani–CSF–Faizanè.
Felix Engelhardt is a German professional racing cyclist, who currently rides for UCI WorldTeam Team Jayco–AlUla.
Walter Calzoni is an Italian racing cyclist, who currently rides for UCI ProTeam Q36.5 Pro Cycling Team.
The 2023 Per sempre Alfredo was the 3rd edition of the Per sempre Alfredo road cycling one day race, which was held on 19 March 2023, starting in the city of Florence and finishing in Alfredo Martini's home town of Sesto Fiorentino.
Matteo Moschetti (ITA)
Felix Engelhardt (GER)
