Phylactery may refer to:
- Amulet, an object believed to confer protection or grace upon its possessor
- Phylactery (Dungeons & Dragons), a Dungeons & Dragons element
- Reliquary, a container for relics
- Speech scroll, an illustrative device denoting speech, song, or other types of sound
- Tefillin, a set of small black leather boxes with leather straps containing scrolls of parchment inscribed with verses from the Torah
