Pinchas Cohen

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Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology, holds the William and Sylvia Kugel Dean's Chair in Gerontology and serves as the executive director of the Ethel Percy Andrus Gerontology Center. He is a USC Distinguished Professor of Gerontology, Medicine, and Biological Sciences. [1]

Cohen graduated in 1986 with highest honors from the medical school at Technion in Israel and trained at Stanford University between 1986 and 1992. He held his first faculty position at the University of Pennsylvania from 1992 to 1999. Until summer 2012, he was a professor and vice chair for research at the Mattel Children's Hospital UCLA at the Ronald Reagan UCLA Medical Center, as well as the co-director of the UCSD/UCLA Diabetes Research Center. [2] [3] He served on the advisory board for the Milken Institute Center for the Future of Aging. [4]

Cohen has received numerous awards for his research, including a National Institute on Aging "EUREKA" Award and the NIH Director Transformative R01 Grant. He also received the Glenn Award for Research in Biological Mechanisms of Aging and the American Federation of Aging Research Irving S. Wright Award of Distinction. [5] He is a Fellow of the American Association for the Advancement of Science and of the Gerontological Society of America as well as a Senior Member of the National Academy of Inventors. [3]

Research

Cohen's research focuses on aging, neurodegeneration, cancer and diabetes with an emphasis on the emerging science of mitochondrial-derived peptides, which he discovered. [6] [7] He has also discussed the possibilities of applying personalized medicine to aging science, coining the term "personalized aging." [8] [9]

His laboratory was one of three teams that independently discovered humanin (Cohen and his team had been screening for proteins that interact with IGFBP3 [10] ). Other mitochondrial peptides discovered by the Cohen laboratory include SHLP 1, 2, 3, 4, 5, and 6 [11] [12] and MOTS-C. [13] [14]

He holds several patents for novel peptides [15] and is the co-founder of CohBar, [16] a biotechnology company developing peptides found in mitochondria for diabetes treatment. [17] He is also the founder of MENTSH Therapeutics. Cohen has published more than 350 papers in top scientific journals. [3]

An expert in the field, Cohen was president of the Growth Hormone Society and served on the Endocrine Society Steering Committee. [18] [19] [20] He has sat on multiple NIH study sections and on several editorial boards. [21]

References

  1. ↑ "Pinchas Cohen, MD". USC Leonard Davis School of Gerontology. University of Southern California. Retrieved 17 March 2025.
  2. ↑ "Pinchas Cohen Named Dean of USC Davis School of Gerontology". USC. Retrieved 23 July 2012.
  3. 1 2 3 "Curriculum Vitae" (PDF). USC Leonard Davis School of Gerontology. Retrieved 17 March 2025.
  4. ↑ "Milken Institute Center for the Future of Aging Assembles Top Experts on Aging." December 1, 2015. http://www.milkeninstitute.org/newsroom/press-releases/view/288.
  5. ↑ "Irving S. Wright Award". American Federation of Aging Research. American Federation of Aging Research. Retrieved 17 March 2025.
  6. ↑ "Cohen Lab". Cohen Lab. USC Leonard Davis School of Gerontology. Retrieved 17 March 2025.
  7. ↑ "Pinchas Cohen". USC Leonard Davis School of Gerontology. Retrieved 3 January 2017.
  8. ↑ "Personalized Aging". Next Avenue. 23 May 2016.
  9. ↑ "USC's Cohen on Personalized Aging, U.S. Health Care". Bloomberg.
  10. ↑ Ikonen, M; Liu, B; Hashimoto, Y; Ma, L; Lee, KW; Niikura, T; Nishimoto, I; Cohen, P (Oct 28, 2003). "Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis". Proceedings of the National Academy of Sciences of the United States of America. 100 (22): 13042–7. Bibcode:2003PNAS..10013042I. doi: 10.1073/pnas.2135111100 . PMC   240741 . PMID   14561895.
  11. ↑ Cobb, L. J., Lee, C., Xiao, J., Yen, K., Wong, R. G., Nakamura, H. K., … Cohen, P. (2016). Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers. Aging, 8(4), 796–808. http://doi.org/10.18632/aging.100943.
  12. ↑ "Small peptides show neuroprotective properties". Alzheimer's News Today. Retrieved 3 January 2017.
  13. ↑ Lee et al., 2015, Cell Metabolism 21, 443–454. March 3, 2015 ª2015 Elsevier Inc. https://dx.doi.org/10.1016/j.cmet.2015.02.009.
  14. ↑ "Newly discovered hormone helps mice lose weight". Popular Science. Retrieved 3 January 2017.
  15. ↑ "Google Patents - Pinchas Cohen" . Retrieved 15 April 2025.
  16. ↑ "Pinchas Cohen, M.D. – Founder and Director – CohBar Inc". cohbar.com. Archived from the original on 2017-01-04.
  17. ↑ "Company Overview of CohBar, Inc". Bloomerg Businessweek. Retrieved 23 July 2012.
  18. ↑ Dunkel, Tom (2010-01-15). "Vigor Quest". The New York Times. Retrieved 23 July 2012.
  19. ↑ "USC Davis School of Gerontology Faculty Profile: Pinchas Cohen, M.D." USC. Retrieved 23 July 2012.
  20. ↑ "Recognizing and Overcoming Adherence Barriers in the Pediatric Setting: An Expert Interview With Pinchas Cohen, MD". Medscape. Retrieved 23 July 2012.
  21. ↑ "Curriculum Vitae" (PDF). USC Leonard Davis School of Gerontology. Retrieved 3 January 2017.
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