Polyoxins are a group of peptidyl nucleoside antibiotics. [1] [2] They are a complex produced by Streptomyces cacaoi var. asoensis and S. piomogenus. [3] Polyoxin compounds contain the same base structure but differ in the composition of certain functional groups. At least fifteen polyoxin compounds are known, designated as polyoxin A, B, C and so forth. Polyoxins A through O are known and all except for 'C' and 'I' have fungicidal activity against phytopathogenic fungi. [3] Some polyoxins have been used as agricultural fungicides because of this.
Polyoxins work by inhibiting the biosynthesis of chitin. [4] [2]
