Projectome

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A projectome is a database or list of all neural connections made by neurons that project from one structure of the nervous system (e.g. a ganglion or a brain nucleus) to another. Thus, a projectome is a subset of a connectome, since a connectome lists not only the connections between the structures, but also within them. Once a complete connectome of an organism is known, the projectome can be derived from it. [1] [2] [3]

Projectomics, a branch of neuroinformatics, is defined as long-range connectomics. [4] Term projectome was introduced in 2007 by Kasthuri and Lichtman. [5]

References

  1. ↑ Chu, Abby (2024-01-05). "Mapping the Projectome Using Compresstome Vibratome". Precisionary. Archived from the original on 2025-04-29. Retrieved 2025-09-29.
  2. ↑ Wildenberg, Gregg; et al. (2023-10-24), A Pipeline for a Primate Projectome: mapping every individual myelinated axon across the whole brain, bioRxiv, doi:10.1101/2023.10.23.563679 , retrieved 2025-09-29
  3. ↑ "Mapping the Brain: The Largest Neuron Projectome Unveiled". Neuroscience News. 2024-02-01. Archived from the original on 2025-07-25. Retrieved 2025-09-29.
  4. ↑ Nguyen, Tri; et al. (2023), The XPRESS Challenge: Xray Projectomic Reconstruction -- Extracting Segmentation with Skeletons, arXiv: 2302.03819
  5. ↑ Kasthuri, Narayanan; Lichtman, Jeff W (2007-04-01). "The rise of the 'projectome'". Nature Methods. 4 (4): 307–308. doi:10.1038/nmeth0407-307. ISSN   1548-7091. PMID   17396125.
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