Reinke's space

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Reinke's space is a potential space between the vocal ligament and the overlying mucosa. [1] It is not an empty space, but contains cells, special fibers and extracellular matrix. It plays an important role in the vibration of the vocal cords. Edema of this space is called Reinke's edema.

Extracellular matrix A structure lying external to one or more cells, which provides structural support for cells or tissues.

In biology, the extracellular matrix (ECM) is a three-dimensional network of extracellular macromolecules, such as collagen, enzymes, and glycoproteins, that provide structural and biochemical support of surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.

Edema abnormal accumulation of fluid in the interstitium

Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain. Clinically, hyperaldosteronism, edema manifests as swelling. The amount of interstitial fluid is determined by the balance of fluid homeostasis and the increased secretion of fluid into the interstitium. The word is from Greek οἴδημα oídēma meaning "swelling". The condition is also known as dropsy.

Reinkes edema

Reinke's edema is the swelling of the vocal cords due to fluid (edema) collected within the Reinke's space. First identified by the German anatomist Friedrich B. Reinke in 1895, the Reinke's space is a gelatinous layer of the vocal cord located underneath the outer cells of the vocal cord. When a person speaks, the Reinke's space vibrates to allow for sound to be produced (phonation). The Reinke's space is sometimes referred to as the superficial lamina propria.

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Vocal cords composed of twin infoldings of mucous membrane stretched horizontally, from back to front, across the larynx. They vibrate, modulating the flow of air being expelled from the lungs during phonation

The vocal cords, also known as vocal folds, are folds of tissue in the throat that are key in creating sounds through vocalization. The size of vocal cords affects the pitch of voice. Open when breathing and vibrating for speech or singing, the folds are controlled via the recurrent laryngeal branch of the vagus nerve.

Cerebral edema human disease

Cerebral edema is excess accumulation of fluid (edema) in the intracellular or extracellular spaces of the brain.

Pulmonary edema fluid accumulation in the air spaces and parenchyma of the lungs

Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs. It leads to impaired gas exchange and may cause respiratory failure. It is due to either failure of the left ventricle of the heart to remove blood adequately from the pulmonary circulation, or an injury to the lung parenchyma or vasculature of the lung. Treatment is focused on three aspects: firstly improving respiratory function, secondly, treating the underlying cause, and thirdly avoiding further damage to the lung. Pulmonary edema, especially acute, can lead to fatal respiratory distress or cardiac arrest due to hypoxia. It is a cardinal feature of congestive heart failure. The term edema is from the Greek οἴδημα, from οἰδέω.

Macular edema Human disease

Macular edema occurs when fluid and protein deposits collect on or under the macula of the eye and causes it to thicken and swell (edema). The swelling may distort a person's central vision, because the macula holds tightly packed cones that provide sharp, clear, central vision to enable a person to see detail, form, and color that is directly in the centre of the field of view.

Stridor is a high-pitched breath sound resulting from turbulent air flow in the larynx or lower in the bronchial tree. It is different from a stertor which is a noise originating in the pharynx. Stridor is a physical sign which is caused by a narrowed or obstructed airway. It can be inspiratory, expiratory or biphasic, although it is usually heard during inspiration. Inspiratory stridor often occurs in children with croup. It may be indicative of serious airway obstruction from severe conditions such as epiglottitis, a foreign body lodged in the airway, or a laryngeal tumor. Stridor should always command attention to establish its cause. Visualization of the airway by medical experts equipped to control the airway may be needed.

<i>Gerhard Reinkes Wanderlust</i> mockumentary television comedy series

Gerhard Reinke's Wanderlust was a mockumentary television comedy broadcast on the American cable channel Comedy Central in Spring 2003. It starred writer-comedian Josh Gardner, appearing under the name, Gerhard Reinke, as a German backpacker with an idiosyncratic style, as he travels around the world on a small budget for the fictional documentary series.

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Hypervolemia, also known as fluid overload, is the medical condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compartment occurs due to an increase in total body sodium content and a consequent increase in extracellular body water. The mechanism usually stems from compromised regulatory mechanisms for sodium handling as seen in congestive heart failure (CHF), kidney failure, and liver failure. It may also be caused by excessive intake of sodium from foods, intravenous (IV) solutions and blood transfusions, medications, or diagnostic contrast dyes. Treatment typically includes administration of diuretics and limit the intake of water, fluids, sodium, and salt.

The pulmonary wedge pressure or PWP, or cross-sectional pressure, is the pressure measured by wedging a pulmonary catheter with an inflated balloon into a small pulmonary arterial branch. It estimates the left atrial pressure.

Andreas Reinke German football player/coach

Andreas Reinke is a German retired footballer who played as a goalkeeper.

Osmotherapy

Osmotherapy is the use of osmotically active substances to reduce the volume of intracranial contents. Osmotherapy serves as the primary medical treatment for cerebral edema. The primary purpose of osmotherapy is to improve elasticity and decrease intracranial volume by removing free water, accumulated as a result of cerebral edema, from brain's extracellular and intracellular space into vascular compartment by creating an osmotic gradient between the blood and brain. Normal serum osmolality ranges from 280-290 mOsm/kg and serum osmolality to cause water removal from brain without much side effects ranges from 300-320 mOsm/kg. Usually, 90 mL of space is created in the intracranial vault by 1.6% reduction in brain water content. Osmotherapy has cerebral dehydrating effects. The main goal of osmotherapy is to decrease intracranial pressure(ICP) by shifting excess fluid from brain. This is accomplished by intravenous administration of osmotic agents which increase serum osmolality in order to shift excess fluid from intracellular or extracellular space of the brain to intravascular compartment. The resulting brain shrinkage effectively reduces intracranial volume and decreases ICP.

Johannes Reinke German botanist

Johannes Reinke was a German botanist and philosopher who was a native of Ziethen, Lauenburg. He is remembered for his research of benthic marine algae.

Histology is the study of the minute structure, composition, and function of tissues. Mature human vocal cords are composed of layered structures which are quite different at the histological level.

Russell Earl Reinke was a Canadian businessman and politician. Reinke was a Liberal party member of the House of Commons of Canada.

Friedrich Berthold Reinke German anatomist

Friedrich Reinke was a German anatomist. Reinke crystals, Reinke's space and Reinke's edema are named after him.

Reinke crystals are rod-like cytoplasmic inclusions which can be found in Leydig cells of the testes. Occurring only in adult humans and wild bush rats, their function is unknown.

40th Scripps National Spelling Bee

The 40th Scripps National Spelling Bee was held in Washington, D.C. at the Mayflower Hotel on June 7–8, 1967, sponsored by the E.W. Scripps Company.

References

Notes

  1. Joiner, Michael C.; Kogel, Albert van der (2016-06-15). Basic Clinical Radiobiology, Fifth Edition. CRC Press. ISBN   9780340808931.