Rylie Green | |
---|---|
Alma mater | University of New South Wales |
Occupation | Bioengineer |
Employer | Imperial College London |
Known for | Biomaterials for regenerative medicine |
Rylie Green is an Australian biomedical engineer who is a Professor at Imperial College London. She works on bioactive conducting polymers for applications in medical electronics.
Green is Australian. [1] She received her PhD in neural interfaces from the School of Biomedical Engineering, University of New South Wales (UNSW) in 2008. [2] [3] She remained at UNSW for her postdoctoral studies, focussing on bioactive and cellular components for tissue engineering. [4]
Green's research focuses on developing new polymer materials for electronics, identifying biomaterials for regenerative medicine and bio-interfacial engineering for neuroprosthetics. [5] She aims to extend the lifetimes of bioelectronic devices such as bionic eyes, robot limbs and brain–computer interface, so they are effective over a patient's life. [6] In Green's research group they improve the mechanical properties of conductive polymers for implant applications, develop characterisation techniques and analyse neural tissue in vitro using techniques such as two photon intravital microscopy. [5]
Green joined Imperial College London in 2016. [2] In 2017 Green received a £1 million grant from EPSRC to explore new polymers for implants, which encourage interaction with surrounding nerves and prevent rejection in the body. She will focus on cochlear implants and new types of bionic eye implants. [7] She is collaborating with Galvani Bioelectronics and Boston Scientific. [8]
She spoke about Improving Implants at the Australian High Commission at the 2017 Pint of Science, and the Science Museum biology themed lates. [9] [1]
Green was one of 16 applicants from 80 to be given a Fresh Science award in 2010, which recognises upcoming scientists throughout Australia. [10] [11] As a part of the award, she gave a presentation of her work on conductive bioplastics at Melbourne Museum. [12]
Green has also received the Rudolf Cimdins Scholarship from the European Society for Biomaterials, which covers the registration costs for attendance at the society's annual conference. [13] [ need quotation to verify ] [14]
In 2017, Green won a Suffrage Science Women in Science Award, which recognises scientific achievements and ability to inspire others. [15]
Biopolymers are natural polymers produced by the cells of living organisms. Like other polymers, biopolymers consist of monomeric units that are covalently bonded in chains to form larger molecules. There are three main classes of biopolymers, classified according to the monomers used and the structure of the biopolymer formed: polynucleotides, polypeptides, and polysaccharides. The Polynucleotides, RNA and DNA, are long polymers of nucleotides. Polypeptides include proteins and shorter polymers of amino acids; some major examples include collagen, actin, and fibrin. Polysaccharides are linear or branched chains of sugar carbohydrates; examples include starch, cellulose and alginate. Other examples of biopolymers include natural rubbers, suberin and lignin, cutin and cutan and melanin.
Bioglass 45S5 or calcium sodium phosphosilicate, is a bioactive glass specifically composed of 45 wt% SiO2, 24.5 wt% CaO, 24.5 wt% Na2O, and 6.0 wt% P2O5. Typical applications of Bioglass 45S5 include: bone grafting biomaterials, repair of periodontal defects, cranial and maxillofacial repair, wound care, blood loss control, stimulation of vascular regeneration, and nerve repair.
Bioactive glasses are a group of surface reactive glass-ceramic biomaterials and include the original bioactive glass, Bioglass. The biocompatibility and bioactivity of these glasses has led them to be used as implant devices in the human body to repair and replace diseased or damaged bones. Most bioactive glasses are silicate based glasses that are degradable in body fluids and can act as a vehicle for delivering ions beneficial for healing. Bioactive glass is differentiated from other synthetic bone grafting biomaterials, in that it is the only one with anti-infective and angiogenic properties.
A biomaterial is a substance that has been engineered to interact with biological systems for a medical purpose, either a therapeutic or a diagnostic one. As a science, biomaterials is about fifty years old. The study of biomaterials is called biomaterials science or biomaterials engineering. It has experienced steady and strong growth over its history, with many companies investing large amounts of money into the development of new products. Biomaterials science encompasses elements of medicine, biology, chemistry, tissue engineering and materials science.
Many opportunities exist for the application of synthetic biodegradable polymers in the biomedical area particularly in the fields of tissue engineering and controlled drug delivery. Degradation is important in biomedicine for many reasons. Degradation of the polymeric implant means surgical intervention may not be required in order to remove the implant at the end of its functional life, eliminating the need for a second surgery. In tissue engineering, biodegradable polymers can be designed such to approximate tissues, providing a polymer scaffold that can withstand mechanical stresses, provide a suitable surface for cell attachment and growth, and degrade at a rate that allows the load to be transferred to the new tissue. In the field of controlled drug delivery, biodegradable polymers offer tremendous potential either as a drug delivery system alone or in conjunction to functioning as a medical device.
Bioelectronics is a field of research in the convergence of biology and electronics.
Anthony "Tony" Guiseppi-Elie, Sc.D., FRSC, FAIMBE, FIEEE, FBMES is a Trinidad born scientist, engineer, educator, administrator, and academic entrepreneur who was Vice President of Academic Affairs and Workforce Development at Tri-County Technical College and an adjunct professor in the Department of Biomedical Engineering of Texas A&M University where he was TEES Research Professor, a member of the founding EnMed Working Group and a founding member of the Texas A&M Academy of Physician-Scientists. He is also founder, President and Scientific director of ABTECH Scientific, Inc. He is noted for his research and commercial development of biologically inspired and chemically responsive polymers, as related to bioanalytics, bioinformatics, bionics and electromics.
Bioceramics and bioglasses are ceramic materials that are biocompatible. Bioceramics are an important subset of biomaterials. Bioceramics range in biocompatibility from the ceramic oxides, which are inert in the body, to the other extreme of resorbable materials, which are eventually replaced by the body after they have assisted repair. Bioceramics are used in many types of medical procedures. Bioceramics are typically used as rigid materials in surgical implants, though some bioceramics are flexible. The ceramic materials used are not the same as porcelain type ceramic materials. Rather, bioceramics are closely related to either the body's own materials or are extremely durable metal oxides.
Gordon Wallace, AO, FAA, FTSE, FIOP, FRACI is a leading scientist in the field of electromaterials. His students and collaborators have pioneered the use of nanotechnology in conjunction with organic conductors to create new materials for energy conversion and storage as well as medical bionics. He has developed new approaches to fabrication that allow material properties discovered in the nano world to be translated into micro structures and macro scopic devices.
Biomaterials are materials that are used in contact with biological systems. Biocompatibility and applicability of surface modification with current uses of metallic, polymeric and ceramic biomaterials allow alteration of properties to enhance performance in a biological environment while retaining bulk properties of the desired device.
Materials that are used for biomedical or clinical applications are known as biomaterials. The following article deals with fifth generation biomaterials that are used for bone structure replacement. For any material to be classified for biomedical applications, three requirements must be met. The first requirement is that the material must be biocompatible; it means that the organism should not treat it as a foreign object. Secondly, the material should be biodegradable ; the material should harmlessly degrade or dissolve in the body of the organism to allow it to resume natural functioning. Thirdly, the material should be mechanically sound; for the replacement of load-bearing structures, the material should possess equivalent or greater mechanical stability to ensure high reliability of the graft.
As with any material implanted in the body, it is important to minimize or eliminate foreign body response and maximize effectual integration. Neural implants have the potential to increase the quality of life for patients with such disabilities as Alzheimer's, Parkinson's, epilepsy, depression, and migraines. With the complexity of interfaces between a neural implant and brain tissue, adverse reactions such as fibrous tissue encapsulation that hinder the functionality, occur. Surface modifications to these implants can help improve the tissue-implant interface, increasing the lifetime and effectiveness of the implant.
Håvard J. Haugen is a Norwegian professor. He is Head of the Department of Biomaterials in Faculty of Dentistry at University of Oslo, Norway.
Róisín Owens is a professor in the Department of Chemical Engineering and Biotechnology, University of Cambridge and a Fellow of Newnham College, Cambridge. Her research investigates new engineering technology for biological applications with a focus on organic bioelectronics, developing electroactive materials that can be used between physical transducers and soft biological tissues.
Jadranka Travaš-Sejdić is a New Zealand academic, and as of 2018 is a professor at the University of Auckland.
Sarah Harriet Cartmell is a British biomaterials scientist and Professor of Bioengineering at the University of Manchester. She specializes on the potential use of electrical regimes to influence cellular activity for orthopaedic tissue engineering applications.
Lizymol Philipose Pamadykandathil is an Indian dental materials scientist. Her work has been recognised with a Nari Shakti Puraskar - the highest civilian honour exclusively for women in India.
Ipsita Roy is a British-Indian materials scientist who is a professor at the University of Sheffield. Her research considers natural polymers of bacterial origin for medical applications. She was elected to the New York Academy of Sciences in 1997 and serves as the Editor of the Journal of Chemical Technology & Biotechnology.
Melissa Ann Grunlan is an American scientist. She is Professor and Holder of the Charles H. and Bettye Barclay Professorship in the Department of Biomedical Engineering at Texas A&M University. She holds courtesy appointments in the Departments of Chemistry and Materials Science & Engineering.
Anne Simmons is an Australian biomedical engineer. She has served as Provost at the University of New South Wales (UNSW) since 2019. Her research is focused on analysis of blood flow in diseased vessels and development of biomaterials for implantable devices.
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