 | This article may be too technical for most readers to understand.(January 2021) |
| SQ2397 | |
|---|---|
 Consensus secondary structure and sequence conservation of Cis-regulator of HTH transcription factor | |
| Identifiers | |
| Symbol | SQ2397 |
| Rfam | RF03532 |
| Other data | |
| RNA type | Cis-reg |
| GO | GO:0051090 |
| SO | SO:0005836 |
| PDB structures | PDBe |
SQ2397 is an element of RNA that was identified by RNA deep sequencing of Clostridioides difficile 630 [1] where it is located immediately upstream of an uncharacterized HTH-type transcriptional regulator.
Homologs are found widely across Bacillota, consistently located 5' of transcriptional regulators of similar size and sequence, which strongly supports a cis-regulatory function.
This RNA is referred to as CD630_SQ2397. [1]
The sequence is highly conserved and shows no evidence for covariation as per R-scape analysis. The proposed secondary structure is therefore purely hypothetical.