| sar RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of sar | |
| Identifiers | |
| Symbol | sar |
| Rfam | RF00262 |
| Other data | |
| RNA type | Gene; antisense |
| Domain(s) | Bacteria; Viruses |
| GO | GO:0003729 |
| SO | SO:0000644 |
| PDB structures | PDBe |
Sar RNA is an antisense non-coding RNA that is partly responsible for the negative regulation of antirepressor synthesis during development of bacteriophage P22. [1] The target of Sar RNA is ant mRNA. Structurally, Sar RNA forms two stem-loops. [1]
Enterobacteria phage λ is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli. It was discovered by Esther Lederberg in 1950. The wild type of this virus has a temperate life cycle that allows it to either reside within the genome of its host through lysogeny or enter into a lytic phase, during which it kills and lyses the cell to produce offspring. Lambda strains, mutated at specific sites, are unable to lysogenize cells; instead, they grow and enter the lytic cycle after superinfecting an already lysogenized cell.
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The Hfq protein encoded by the hfq gene was discovered in 1968 as an Escherichia coli host factor that was essential for replication of the bacteriophage Qβ. It is now clear that Hfq is an abundant bacterial RNA binding protein which has many important physiological roles that are usually mediated by interacting with Hfq binding sRNA.
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