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| Abbreviation | SCOT |
|---|---|
| Founded at | Kingdom of Saudi Arabia |
| Fields | Organ transplantation |
Director General | Talal Algoufi |
The Saudi Center for Organ Transplantation (SCOT), was established in 1985. [1] It was formerly known as the National Kidney Foundation (Saudi), until it was renamed in 1993, and is a centre for the transplantation of organs in the Kingdom of Saudi Arabia. Its Director General is Talal Algoufi.
Organ donation is the process when a person authorizes an organ of their own to be removed and transplanted to another person, legally, either by consent while the donor is alive, through a legal authorization for deceased donation made prior to death, or for deceased donations through the authorization by the legal next of kin.
In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system.
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.
A head transplant is an experimental surgical operation involving the grafting of one organism's head onto the body of another. In many experiments, the recipient's head has not been removed, but in others it has been. Experimentation in animals began in the early 1900s. As of 2024, no lasting successes have been achieved.
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with the healthy liver from another person (allograft). Liver transplantation is a treatment option for end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The most common technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic position as the original liver. The surgical procedure is complex, requiring careful harvest of the donor organ and meticulous implantation into the recipient. Liver transplantation is highly regulated, and only performed at designated transplant medical centers by highly trained transplant physicians and supporting medical team. Favorable outcomes require careful screening for eligible recipients, as well as a well-calibrated live or deceased donor match.
Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue. Transplant rejection can be lessened by determining the molecular similitude between donor and recipient and by use of immunosuppressant drugs after transplant.
Xenotransplantation, or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation, syngeneic transplantation or isotransplantation and autotransplantation. Xenotransplantation is an artificial method of creating an animal-human chimera, that is, a human with a subset of animal cells. In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid.
Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). Kidney transplant is typically classified as deceased-donor or living-donor transplantation depending on the source of the donor organ. Living-donor kidney transplants are further characterized as genetically related (living-related) or non-related (living-unrelated) transplants, depending on whether a biological relationship exists between the donor and recipient. The first successful kidney transplant was performed in 1954 by a team including Joseph Murray, the recipient's surgeon, and Hartwell Harrison, surgeon for the donor. Murray was awarded a Nobel Prize in Physiology or Medicine in 1990 for this and other work. In 2018, an estimated 95,479 kidney transplants were performed worldwide, 36% of which came from living donors.
Organ transplantation in China has taken place since the 1960s, and is one of the largest organ transplant programmes in the world, peaking at over 13,000 liver and kidney transplants a year in 2004.
Organ procurement is a surgical procedure that removes organs or tissues for reuse, typically for organ transplantation.
The multi-billion rupee Gurgaon kidney scandal came to light in January 2008 when police arrested several people for running a kidney transplant racket in Gurgaon, an industrial township near New Delhi, India. Kidneys of most of the victims, who were the poor hailing from the nearby western Uttar Pradesh, were transplanted into clients from the United States, United Kingdom, Canada, Saudi Arabia and Greece. The police raid was prompted by complaints by the locals from Moradabad about illegal kidney sales. The man accused of the scandal, Amit Kumar, was arrested in Nepal on 7 February 2008 and denied any hand in criminal activity.
Organ trade is the trading of human organs, tissues, or other body products, usually for transplantation. According to the World Health Organization (WHO), organ trade is a commercial transplantation where there is a profit, or transplantations that occur outside of national medical systems. There is a global need or demand for healthy body parts for transplantation, which exceeds the numbers available.
Organ theft is the act of taking a person's organs for transplantation or sale on the black market, without their explicit consent through means of being an organ donor or other forms of consent. Most cases of organ theft involve coercion, occurrences in wartime, or thefts within hospital settings. Organ theft is a commonly used trope in speculative fiction.
The practice of selling one's kidney for profit in Iran is legal and regulated by the government. In any given year, it is estimated that 1400 Iranians sell one of their kidneys to a recipient who was previously unknown to them. Iran currently is the only country in the world that allows the sale of one's kidney for compensation ; consequently, the country does not have either a waiting list or a shortage of available organs.
The Ontario Online Donor Registry is a website where Ontario residents, age 16 and older, can register their consent to be an organ and tissue donor. This registry was created to help ease questions and ambiguities with organ donor wishes. The virtual registry also increases Ontario donations with increased accessibility. The registration process can be done through beadonor.ca. Online donor registries have also become popular in the United States, where one can register through Donate Life America; Malaysia, registering through their National Transplant Registry; and Saudi Arabia, registering through the Saudi Center for Organ Transplantation.
King Fahad Specialist Hospital-Dammam (KFSHD) is a district general hospital in the Eastern region of Saudi Arabia.
Organ transplantation is a common theme in science fiction and horror fiction. Numerous horror movies feature the theme of transplanted body parts that are evil or give supernatural powers, with examples including Body Parts, Hands of a Stranger, and The Eye.
Allegations of forced organ harvesting from Falun Gong practitioners and other political prisoners in China have raised concern within the international community. According to a report by former lawmaker David Kilgour, human rights lawyer David Matas and journalist Ethan Gutmann of the Victims of Communism Memorial Foundation, political prisoners, mainly Falun Gong practitioners, are being executed "on demand" in order to provide organs for transplant to recipients. Reports have said that organ harvesting has been used to advance the Chinese Communist Party's persecution of Falun Gong and because of the financial incentives available to the institutions and individuals involved in the trade. A report by The Washington Post has disputed some of the allegations, saying that China does not import sufficient quantities of immunosuppressant drugs, used by transplant recipients, to carry out such quantities of organ harvesting.
Faissal Shaheen is a Saudi nephrologist and co-founder of the Jeddah kidney center in King Fahad Hospital Jeddah and the Saudi Center for Organ Transplantation. In 2003 he led the Saudi team involved in the first kidney transplantation in the Arab World, in Aden, Yemen. He is the president of the International Society for Organ Donation and Procurement from 2019 to 2021.
Organ donation in India is regulated by the Transplantation of Human Organs and Tissues Act, 1994. The law allows both deceased and living donors to donate their organs. It also identifies brain death as a form of death. The National Organ and Tissue Transplant Organisation (NOTTO) functions as the apex body for activities of relating to procurement, allotment and distribution of organs in the country.
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