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Sequenceome is the totality of polymer sequences on Earth. Sequences in biology such as genome and proteome are the major components. Sequenceome is effectively a large database.
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Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for in silico analyses of biological queries using mathematical and statistical techniques.
Deoxyribonucleic acid is a molecule composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life.
In mathematics, the Fibonacci numbers, commonly denoted Fn, form a sequence, called the Fibonacci sequence, such that each number is the sum of the two preceding ones, starting from 0 and 1. That is,
In the fields of molecular biology and genetics, a genome is all genetic material of an organism. It consists of DNA. The genome includes both the genes and the noncoding DNA, as well as mitochondrial DNA and chloroplast DNA. The study of the genome is called genomics. The genome for several organisms have been sequenced and genes analyzed, the human genome project which sequenced the entire genome for Homo sapiens was successfully completed in April 2003.
In astronomy, the main sequence is a continuous and distinctive band of stars that appears on plots of stellar color versus brightness. These color-magnitude plots are known as Hertzsprung–Russell diagrams after their co-developers, Ejnar Hertzsprung and Henry Norris Russell. Stars on this band are known as main-sequence stars or dwarf stars. These are the most numerous true stars in the universe, and include the Earth's Sun.
Polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation. It is fundamental to many of the procedures used in genetic testing and research, including analysis of ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications including biomedical research and criminal forensics.
In mathematics, a sequence is an enumerated collection of objects in which repetitions are allowed and order matters. Like a set, it contains members. The number of elements is called the length of the sequence. Unlike a set, the same elements can appear multiple times at different positions in a sequence, and unlike a set, the order does matter. Formally, a sequence can be defined as a function from natural numbers to the elements at each position. The notion of a sequence can be generalized to an indexed family, defined as a function from an index set that may not be numbers to another set of elements.
The Transmission Control Protocol (TCP) is one of the main protocols of the Internet protocol suite. It originated in the initial network implementation in which it complemented the Internet Protocol (IP). Therefore, the entire suite is commonly referred to as TCP/IP. TCP provides reliable, ordered, and error-checked delivery of a stream of octets (bytes) between applications running on hosts communicating via an IP network. Major internet applications such as the World Wide Web, email, remote administration, and file transfer rely on TCP, which is part of the Transport Layer of the TCP/IP suite. SSL/TLS often runs on top of TCP.
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells consist of three billion DNA base pairs, while diploid genomes have twice the DNA content. While there are significant differences among the genomes of human individuals, these are considerably smaller than the differences between humans and their closest living relatives, the bonobos and chimpanzees.
ANSI escape sequences are a standard for in-band signaling to control cursor location, color, font styling, and other options on video text terminals and terminal emulators. Certain sequences of bytes, most starting with an ASCII escape character and a bracket character, are embedded into text. The terminal interprets these sequences as commands, rather than text to display verbatim.
A music sequencer is a device or application software that can record, edit, or play back music, by handling note and performance information in several forms, typically CV/Gate, MIDI, or Open Sound Control (OSC), and possibly audio and automation data for DAWs and plug-ins.
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. The NCBI is located in Bethesda, Maryland and was founded in 1988 through legislation sponsored by US Congressman Claude Pepper.
Action fiction is the literary genre that includes spy novels, adventure stories, tales of terror and intrigue and mysteries. This kind of story utilizes suspense, the tension that is built up when the reader wishes to know how the conflict between the protagonist and antagonist is going to be resolved or what the solution to the puzzle of a thriller is.
1000 or one thousand is the natural number following 999 and preceding 1001. In most English-speaking countries, it is often written with a comma separating the thousands digit: 1,000.
A protein family is a group of evolutionarily-related proteins. In many cases a protein family has a corresponding gene family, in which each gene encodes a corresponding protein with a 1:1 relationship. The term protein family should not be confused with family as it is used in taxonomy.
The On-Line Encyclopedia of Integer Sequences (OEIS) is an online database of integer sequences. It was created and maintained by Neil Sloane while researching at AT&T Labs. He transferred the intellectual property and hosting of the OEIS to the OEIS Foundation in 2009. Sloane is president of the OEIS Foundation.
One million (1,000,000), or one thousand thousand, is the natural number following 999,999 and preceding 1,000,001. The word is derived from the early Italian millione, from mille, "thousand", plus the augmentative suffix -one. It is commonly abbreviated in British English as m, M, MM, mm, or mn in financial contexts.
1,000,000,000 is the natural number following 999,999,999 and preceding 1,000,000,001. One billion can also be written as b or bn.
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery.
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature. It is maintained by the UniProt consortium, which consists of several European bioinformatics organisations and a foundation from Washington, DC, United States.