sroB RNA | |
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![]() Predicted secondary structure and sequence conservation of sroB | |
Identifiers | |
Symbol | sroB |
Rfam | RF00368 |
Other data | |
RNA type | Gene; sRNA |
Domain(s) | Bacteria |
SO | SO:0000655 |
PDB structures | PDBe |
The sroB RNA (also known as MicM, rybC, or ChiX) is a non-coding RNA gene of 90 nucleotides in length. sroB is found in several Enterobacterial species, but its function is unknown. [1] [2] SroB is found in the intergenic region on the opposite strand to the ybaK and ybaP genes. [1] SroB is expressed in stationary phase. [1] Experiments have shown that SroB is a Hfq binding sRNA. [2] [3]
Further evidence has shown that SroB negatively regulates the outer membrane protein YbfM by sequestering the ribosome binding site of ybfM mRNA by an antisense interaction. [4] SroB also regulates the DpiA/DpiB two-component system. [5] Furthermore, SroB itself appears to be the target of a non-coding transcript from the chbBC intergenic region. [6] [7] [8]