Stereotactic injection

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Stereotactic injection is a procedure in which a computer and a 3-dimensional scanning device are used to inject anticancer drugs directly into a tumor.

Stereotactic injection may also refer to the use of injections during stereotactic surgery to precisely target specific sites, such as brain regions, during experimental research. [1] [2]

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Neurosurgery Medical specialty of disorders which affect any portion of the nervous system

Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the prevention, diagnosis, surgical treatment, and rehabilitation of disorders which affect any portion of the nervous system including the brain, spinal cord, central and peripheral nervous system, and cerebrovascular system.

Rectal prolapse Medical condition

Rectal prolapse is when the rectal walls have prolapsed to a degree where they protrude out the anus and are visible outside the body. However, most researchers agree that there are 3 to 5 different types of rectal prolapse, depending on if the prolapsed section is visible externally, and if the full or only partial thickness of the rectal wall is involved.

Infantile hemangioma Raised red skin lesion that affects infants caused by benign vascular tumor

An infantile hemangioma (IH), sometimes called a strawberry mark due to appearance, is a type of benign vascular tumor or anomaly that affects babies. Other names include capillary hemangioma, strawberry hemangioma, and strawberry nevus. They appear as a red or blue raised lesion on the skin. Typically, they begin during the first four weeks of life, growing until about five months of life, and then shrinking in size and disappearing over the next few years. Often skin changes remain after they shrink. Complications may include pain, bleeding, ulcer formation, heart failure, or disfigurement. It is the most common tumor of orbit and periorbital areas in childhood. It may occur in the skin, subcutaneous tissues and mucous membranes of oral cavities and lips as well as in the liver, spleen and kidneys.

Minimally invasive procedure

Minimally invasive procedures encompass surgical techniques that limit the size of incisions needed and so lessen wound healing time, associated pain and risk of infection. Surgery by definition is invasive and many operations requiring incisions of some size are referred to as open surgery, in which incisions made can sometimes leave large wounds that are painful and take a long time to heal. Minimally invasive procedures have been enabled by the advance of various medical technologies. An endovascular aneurysm repair as an example of minimally invasive surgery is much less invasive in that it involves much smaller incisions than the corresponding open surgery procedure of open aortic surgery. This minimally invasive surgery became the most common method of repairing abdominal aortic aneurysms in 2003 in the United States.

Stereotactic surgery Medical procedure

Stereotactic surgery is a minimally invasive form of surgical intervention that makes use of a three-dimensional coordinate system to locate small targets inside the body and to perform on them some action such as ablation, biopsy, lesion, injection, stimulation, implantation, radiosurgery (SRS), etc.

Prostatectomy Surgical removal of all or part of the prostate gland

Prostatectomy as a medical term refers to the surgical removal of all or part of the prostate gland. This operation is done for benign conditions that cause urinary retention, as well as for prostate cancer and for other cancers of the pelvis.

Inferior mesenteric lymph nodes

The inferior mesenteric lymph nodes consist of:

Post-chemotherapy cognitive impairment (PCCI) describes the cognitive impairment that can result from chemotherapy treatment. Approximately 20 to 30% of people who undergo chemotherapy experience some level of post-chemotherapy cognitive impairment. The phenomenon first came to light because of the large number of breast cancer survivors who complained of changes in memory, fluency, and other cognitive abilities that impeded their ability to function as they had pre-chemotherapy.

Injection lipolysis is a controversial cosmetic procedure in which drug mixtures are injected into patients with the goal of destroying fat cells. This practice, using drugs generally based on phosphatidylcholine and deoxycholate (PCDC), evolved from the initial intravenous use of those drug formulations to treat blood disorders.

Currarino syndrome Medical condition

Currarino syndrome is an inherited congenital disorder where either the sacrum is not formed properly, or there is a mass in the presacral space in front of the sacrum, and there are malformations of the anus or rectum. It occurs in approximately 1 in 100,000 people.

The National Centre for Text Mining (NaCTeM) is a publicly funded text mining (TM) centre. It was established to provide support, advice, and information on TM technologies and to disseminate information from the larger TM community, while also providing tailored services and tools in response to the requirements of the United Kingdom academic community.

Medullary breast carcinoma Rare type of breast cancer

Medullary breast carcinoma is a rare type of breast cancer that is characterized as a relatively circumscribed tumor with pushing, rather than infiltrating, margins. It is histologically characterized as poorly differentiated cells with abundant cytoplasm and pleomorphic high grade vesicular nuclei. It involves lymphocytic infiltration in and around the tumor and can appear to be brown in appearance with necrosis and hemorrhage. Prognosis is measured through staging but can often be treated successfully and has a better prognosis than other infiltrating breast carcinomas.

Mucinous carcinoma Medical condition

Mucinous carcinoma is a type of cancer that arises from epithelial cells; these line certain internal organs and skin, and produce mucin. Over 40 percent of all mucinous carcinomas are colorectal.

Prospective cohort study Longitudinal cohort study

A prospective cohort study is a longitudinal cohort study that follows over time a group of similar individuals (cohorts) who differ with respect to certain factors under study, to determine how these factors affect rates of a certain outcome. For example, one might follow a cohort of middle-aged truck drivers who vary in terms of smoking habits, to test the hypothesis that the 20-year incidence rate of lung cancer will be highest among heavy smokers, followed by moderate smokers, and then nonsmokers.

N-localizer

The N-localizer is a device that enables guidance of stereotactic surgery or radiosurgery using tomographic images that are obtained via computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET). The N-localizer comprises a diagonal rod that spans two vertical rods to form an N-shape and permits calculation of the point where a tomographic image plane intersects the diagonal rod. Attaching three N-localizers to a stereotactic instrument allows calculation of three points where a tomographic image plane intersects three diagonal rods. These points determine the spatial orientation of the tomographic image plane relative to the stereotactic frame.

With an estimated 120,000 people living with HIV/AIDS, the HIV/AIDS epidemic in Colombia is consistent with the epidemic in much of Latin America as a whole, both in terms of prevalence of infection and characteristics of transmission and affected populations. Colombia has a relatively low rate of HIV infection at 0.4%, though certain groups, particularly men who have sex with men, bear the burden of significantly higher rates of infection than the general population. Colombia's health care system and conception of a "right to health," created by the T-760 decision of 2008, have revolutionized access to HIV treatment. Despite this, the quality of health insurance and treatment for HIV has often been disputed.

The management of strabismus may include the use of drugs or surgery to correct the strabismus. Agents used include paralytic agents such as botox used on extraocular muscles, topical autonomic nervous system agents to alter the refractive index in the eyes, and agents that act in the central nervous system to correct amblyopia.

Subramanian Kalyanaraman is an Indian neurosurgeon and a former head of the Department of Neurosurgery at Apollo Hospitals, Chennai. He was known for his pioneering techniques in stereotactic surgery and is an elected fellow of a number of science and medical academies including the National Academy of Medical Sciences and the Indian Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1969.

Santosh Gajanan Honavar is a renowned Indian ophthalmologist and is currently the editor of the Indian Journal of Ophthalmology and Indian Journal of Ophthalmology - Case Reports, the official journals of the All India Ophthalmological Society; Director, Medical Services ; Director, Department of Ocular Oncology and Oculoplasty at Centre for Sight, Hyderabad; and Director, National Retinoblastoma Foundation. A former head of the Department of Ophthalmic Plastic Surgery and Ocular Oncology and associate director at L. V. Prasad Eye Institute, he is known for his research on retinoblastoma. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to Medical Sciences in 2009.. He is counted among the top 2% of world researchers and among the top 10 Indian ophthalmologists in research. Dr Honavar is the only Indian Ophthalmologist to receive the Lifetime Achievement Award by the American Academy of Ophthalmology and the Honorary Fellowship of the Royal College of Ophthalmologists, London, UK.

Dan Theodorescu is the Director of the Samuel Oschin Comprehensive Cancer Institute at the Cedars-Sinai Medical Center and leader of Cedars-Sinai CANCER. From 2010 until 2018, Theodorescu was Director of the University of Colorado Cancer Center and a professor of Surgery-Urology. He has been appointed Paul Mellon Chair at the University of Virginia and Paul Bunn Chair and Distinguished University Professor at the University of Colorado

References

  1. Geiger, B. M., Frank, L. E., Caldera-Siu, A. D., Pothos, E. N. (2008). "Survivable Stereotaxic Surgery in Rodents". Journal of Visualized Experiments (20): e880. doi:10.3791/880. PMC   3233859 . PMID   19078946.CS1 maint: multiple names: authors list (link)
  2. McSweeney, C., Mao, Y. (2015). "Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors". Journal of Visualized Experiments (99). doi:10.3791/52653. PMC   4542605 . PMID   25992973.CS1 maint: multiple names: authors list (link)

PD-icon.svg This article incorporates  public domain material from the U.S. National Cancer Institute document: "Dictionary of Cancer Terms".