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Steven Brem is an American neurosurgeon at the Perelman School of Medicine at the University of Pennsylvania. [1] He graduated from Harvard School of Medicine and completed his residency at Massachusetts General Hospital. [2] [3]
Brem authored the comprehensive glioblastoma textbook "Glioblastoma". [4]
Jackson State University is a public historically black university in Jackson, Mississippi. It is one of the largest HBCUs in the United States and the fourth largest university in Mississippi. The university is a member of the Thurgood Marshall College Fund and classified among "R2: Doctoral Universities – High research activity".
Loperamide, sold under the brand name Imodium, among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in inflammatory bowel disease and short bowel syndrome. It is not recommended for those with blood in the stool, mucus in the stool, or fevers. The medication is taken by mouth.
The University of San Diego (USD) is a private Roman Catholic research university in San Diego, California. Chartered in July 1949 as the independent San Diego College for Women and San Diego University, the academic institutions merged in 1972 into the University of San Diego. Since then, the university has grown to comprise nine undergraduate and graduate schools, to include the Shiley-Marcos School of Engineering, Joan B. Kroc School of Peace Studies, and School of Law. USD has 89 undergraduate and graduate programs, and enrolls approximately 9,073 undergraduate, paralegal, graduate and law students. It is classified among "R2: Doctoral Universities – High research activity".
Doogie Howser, M.D. is an American medical drama that ran for four seasons on ABC from September 19, 1989, to March 24, 1993, totaling 97 episodes. Created by Steven Bochco and David E. Kelley, the show stars Neil Patrick Harris in the title role as a teenage physician who balances the challenge of practicing medicine with the everyday problems of teenage life.
Glioblastoma, also known as glioblastoma multiforme (GBM), is the most aggressive type of cancer that begins within the brain. Initially, signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke. Symptoms often worsen rapidly and may progress to unconsciousness.
Bevacizumab, sold under the brand name Avastin, is a medication used to treat a number of types of cancers and a specific eye disease. For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, glioblastoma, and renal-cell carcinoma. In many of these diseases it is used as a first-line therapy. For age-related macular degeneration it is given by injection into the eye (intravitreal).
Procarbazine is a chemotherapy medication used for the treatment of Hodgkin's lymphoma and brain cancers. For Hodgkin's it is often used together with chlormethine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine. It is typically taken by mouth.
The Duke University School of Medicine, commonly known as Duke Med, is the medical school of Duke University. It is located in the Collegiate Gothic-style West Campus of Duke University in Durham, North Carolina. The School of Medicine, along with the Duke University School of Nursing, Duke University Hospital, Duke Regional Hospital, Duke Children's Hospital, Duke Raleigh Hospital, and other affiliated hospitals, clinics, and laboratories, make up the Duke University Health System. Established in 1925 by James B. Duke, the School of Medicine has earned its reputation as an integral part of one of the world's foremost patient care and biomedical research institutions.
Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent.
Cilengitide is a molecule designed and synthesized at the Technical University Munich in collaboration with Merck KGaA in Darmstadt. It is based on the cyclic peptide cyclo(-RGDfV-), which is selective for αv integrins, which are important in angiogenesis, and other aspects of tumor biology. Hence, it is under investigation for the treatment of glioblastoma, where it may act by inhibiting angiogenesis, and influencing tumor invasion and proliferation.
Brem is traditional fermented food or fermented beverage from Indonesia. There are two types of brem, brem cake (solid) that is usually eaten as snack from Madiun and Wonogiri, and brem beverage (liquid) made of rice wine from Bali and Nusa Tenggara, but mostly known from Bali. Brem first appeared in Java around the year 1000, based on investigations regarding old Javanese inscriptions and literature.
Kendrick Kang-Joh Jeong is an American stand-up comedian, actor, producer, writer, television personality and licensed physician. He has appeared in the films Knocked Up (2007), Role Models (2008), Furry Vengeance (2010), Ride Along 2 (2016), Crazy Rich Asians (2018), and Tom and Jerry (2021). Jeong is best known for portraying Leslie Chow in The Hangover film series (2009–2013) and Ben Chang in NBC's Community (2009–2015) and was the lead in the ABC sitcom Dr. Ken (2015–2017). He was also the creator, writer, and executive producer of Dr. Ken.
NYU Langone Health is an academic medical center located in New York City, New York, United States, affiliated with New York University. NYU Langone comprises NYU Grossman School of Medicine and several inpatient facilities: Tisch Hospital, Kimmel Pavilion, NYU Langone Orthopedic Hospital, Hassenfeld Children's Hospital, NYU Langone Hospital-Brooklyn and NYU Langone Hospital-Long Island. It is also home to Rusk Rehabilitation. NYU Langone Health operates over 350 locations in the New York area. The Manhattan campus of NYU Langone Health overlooks the East River.
John P. A. Ioannidis is a Greek-American physician-scientist, writer and Stanford University professor who has made contributions to evidence-based medicine, epidemiology, and clinical research. Ioannidis studies scientific research itself, meta-research primarily in clinical medicine and the social sciences.
A bill of rights, sometimes called a declaration of rights or a charter of rights, is a list of the most important rights to the citizens of a country. The purpose is to protect those rights against infringement from public officials and private citizens.
Temozolomide (TMZ), sold under the brand name Temodar among others, is a medication used to treat some brain tumors such as glioblastoma multiforme or anaplastic astrocytoma. It is taken by mouth or via intravenous infusion.
Cabozantinib, sold under the brand names Cometriq and Cabometyx among others, is a medication used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma. It is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET. It was discovered and developed by Exelixis Inc.
William G. Kaelin Jr. is an American Nobel Laureate physician-scientist. He is a professor of medicine at Harvard University and the Dana-Farber Cancer Institute. His laboratory studies tumor suppressor proteins. In 2016, Kaelin received the Albert Lasker Award for Basic Medical Research and the AACR Princess Takamatsu Award. He also won the Nobel Prize in Physiology or Medicine in 2019 along with Peter J. Ratcliffe and Gregg L. Semenza.
Malcolm Francis Graham Stevens OBE, FRS is an English chemist and Emeritus professor of the University of Nottingham, having previously worked at Aston University where he developed the cancer drug temozolomide.