Steven Shafer is a professor of anesthesiology at Stanford University. In 2011, the International Society of Anaesthetic Pharmacology gave him their lifetime achievement award. [1]
Shafer graduated from Princeton University with an A.B. He received his M.D. from Stanford and completed his anesthesia residency at the University of Pennsylvania. [2]
Shafer is the former (2006-2016) editor-in-chief of Anesthesia & Analgesia . He specializes in the clinical pharmacology of intravenous anesthetic drugs. Shafer left Stanford in 2007 to go to Columbia University College of Physicians and Surgeons as a professor of anesthesiology. In 2012, Shafer returned to Stanford as an anesthesia professor in the Stanford University Medical Center. In addition, he is adjunct associate professor of bioengineering and therapeutic sciences at the University of California, San Francisco. [3]
Shafer was a co-founder of PharmacoFore, which subsequently changed its name to Signature Therapeutics. [2] [ citation needed ] He has held executive positions at other companies, including Pharsight and two software development companies. [2]
Shafer appeared as an expert witness in the Michael Jackson manslaughter trial. [4] [5]
Propofol, marketed as Diprivan, among other names, also known as 2,6-Diisopropylphenol, is a short-acting medication that results in a decreased level of consciousness and a lack of memory for events. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. It is also used for status epilepticus if other medications have not worked. It is given by injection into a vein, and the maximum effect takes about two minutes to occur and typically lasts five to ten minutes. Propofol is also used for euthanasia in Canada.
Epidural administration is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord. The epidural route is used by physicians and nurse anesthetists to administer local anesthetic agents, analgesics, diagnostic medicines such as radiocontrast agents, and other medicines such as glucocorticoids. Epidural administration involves the placement of a catheter into the epidural space, which may remain in place for the duration of the treatment. The technique of intentional epidural administration of medication was first described in 1921 by Spanish military surgeon Fidel Pagés.
Remifentanil, marketed under the brand name Ultiva is a potent, short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. The use of remifentanil has made possible the use of high-dose opioid and low-dose hypnotic anesthesia, due to synergism between remifentanil and various hypnotic drugs and volatile anesthetics.
Methoxyflurane, sold under the brand name Penthrox among others, is an inhaled medication primarily used to reduce pain following trauma. It may also be used for short episodes of pain as a result of medical procedures. Onset of pain relief is rapid and of a short duration. Use is only recommended with direct medical supervision.
Mivacurium chloride is a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Cisatracurium besilate is a bisbenzyltetrahydroisoquinolinium that has effect as a neuromuscular-blocking drug non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It shows intermediate duration of action. Cisatracurium is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture.
Dexmedetomidine, sold under the trade name Precedex among others, is a drug used in humans for sedation. Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. It is also used in humans to treat acute agitation associated with schizophrenia or bipolar I or II disorder.
Jean Emily Henley from was an anesthesiologist. She was the only child of Eugene Henry and Helen Esther Heller, who emigrated from Hungary and Germany respectively into the United States. She was fluent in German, due to that being her parents native language. The father changed the family surname to Henley while she was still a child. Both parents practiced lay psychotherapy and later obtained PhDs. As both a sculptor and linguist, she had many accomplishments.
Paul Frederick White, FANZCA is a researcher in anesthesiology, research consultant at Cedars-Sinai Medical Center at Los Angeles, retired professor and former holder of the Margaret Milam McDermott Distinguished Chair of Anesthesiology at The University of Texas Southwestern Medical Center at Dallas, and the author and editor of several journals and textbooks on the subject. With over 450 peer-reviewed publications and authorship in 9 anesthesiology textbooks, White has helped shape and revolutionize the field of ambulatory anesthesia and intravenous anesthesia.
The Outcomes Research Consortium is an international clinical research group that focuses on the perioperative period, along with critical care and pain management. The Consortium's aim is to improve the quality of care for surgical, critical care, and chronic pain patients and to "Provide the evidence for evidence-based practice." Members of the Consortium are especially interested in testing simple, low-risk, and inexpensive treatments that have the potential to markedly improve patients' surgical experiences.
Gantacurium chloride is a new experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Gantacurium is not yet available for widespread clinical use: it is currently undergoing Phase III clinical development.
BW A444U was an experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, intended to be used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It was synthesized and developed in the early 1980s.
Mervyn Maze, MD, MB ChB has been a Professor in the Departments of Anesthesia and Pain Medicine, Intensive Care at the University of California, San Francisco since 1988. He has also served as Professor and Chair at Imperial College London.
Obstetric anesthesia or obstetric anesthesiology, also known as ob-gyn anesthesia or ob-gyn anesthesiology, is a sub-specialty of anesthesiology that provides peripartum pain relief (analgesia) for labor and anesthesia for cesarean deliveries ('C-sections').
Robert Marvin Epstein is an American anesthesiologist, a member of the National Academy of Medicine, and the Harold Carron Professor of Anesthesiology (emeritus) at the University of Virginia.
James Edward Cottrell is the Chair Emeritus, Department of Anesthesiology at SUNY Downstate Medical Center in New York City. He serves as a member of the New York State Board of Regents and is an avid collector of contemporary fine-art.
Alex Bekker is a physician, author and academic. He is a professor and chair at the Department of Anesthesiology, Rutgers New Jersey Medical School. He is also professor at the Department of Physiology, Pharmacology & Neurosciences. He serves as the Chief of Anesthesiology Service at the University Hospital in Newark.
Total intravenous anesthesia (TIVA) refers to the intravenous administration of anesthetic agents to induce a temporary loss of sensation or awareness. The first study of TIVA was done in 1872 using chloral hydrate, and the common anesthetic agent propofol was licensed in 1986. TIVA is currently employed in various procedures as an alternative technique of general anesthesia in order to improve post-operative recovery.
Alex Macario is an American anesthesiologist, academic and author. He is a vice-chair for education, a professor in the Department of Anesthesiology, Perioperative and Pain Medicine, and program director for the anesthesiology residency at Stanford University School of Medicine.
Talmage D. Egan is an anesthesiologist, academic, entrepreneur, and author. He is a professor and chair in the department of anesthesiology, and an adjunct professor in the departments of pharmaceutics, bioengineering, and neurosurgery at the University of Utah School of Medicine.