Pathology is the study of disease and injury. The word pathology also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area that includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue and human cell samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases, and the affix pathy is sometimes used to indicate a state of disease in cases of both physical ailment and psychological conditions. A physician practicing pathology is called a pathologist.
Anatomical pathology (Commonwealth) or anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues. Over the 20th century, surgical pathology has evolved tremendously: from historical examination of whole bodies (autopsy) to a more modernized practice, centered on the diagnosis and prognosis of cancer to guide treatment decision-making in oncology. Its modern founder was the Italian scientist Giovanni Battista Morgagni from Forlì.
Forensic pathology is pathology that focuses on determining the cause of death by examining a corpse. A post mortem examination is performed by a medical examiner or forensic pathologist, usually during the investigation of criminal law cases and civil law cases in some jurisdictions. Coroners and medical examiners are also frequently asked to confirm the identity of remains.
Sudden infant death syndrome (SIDS), sometimes known as cot death, is the sudden unexplained death of a child of less than one year of age. Diagnosis requires that the death remain unexplained even after a thorough autopsy and detailed death scene investigation. SIDS usually occurs during sleep. Typically death occurs between the hours of midnight and 9:00 a.m. There is usually no noise or evidence of struggle. SIDS remains the leading cause of infant mortality in Western countries, constituting half of all post-neonatal deaths.
Positional asphyxia, also known as postural asphyxia, is a form of asphyxia which occurs when someone's position prevents the person from breathing adequately. People may die from positional asphyxia accidentally, when the mouth and nose are blocked, or where the chest may be unable to fully expand.
The medical examiner is an appointed official in some American jurisdictions that investigates deaths that occur under unusual or suspicious circumstances, to perform post-mortem examinations, and in some jurisdictions to initiate inquests. They are necessarily trained in pathology.
Sidney Farber was an American pediatric pathologist. He is regarded as the father of modern chemotherapy for his work using folic acid antagonists to combat leukemia, which led to the development of other chemotherapeutic agents against other malignancies. Farber was also active in cancer research advocacy and fundraising, most notably through his establishment of the Jimmy Fund, a foundation dedicated to pediatric research in childhood cancers. The Dana–Farber Cancer Institute is named after him.
Robert Royston Amos Coombs FRS FRCPath FRCP was a British immunologist, co-discoverer of the Coombs test (1945) used for detecting antibodies in various clinical scenarios, such as Rh disease and blood transfusion.
Clinical pathology is a medical specialty that is concerned with the diagnosis of disease based on the laboratory analysis of bodily fluids, such as blood, urine, and tissue homogenates or extracts using the tools of chemistry, microbiology, hematology, molecular pathology, and Immunohaematology. This specialty requires a medical residency.
Waneta Ethel (Nixon) Hoyt was an American serial killer who was convicted of killing all five of her biological children.
Charles Randal Smith is a former Canadian pathologist known for performing flawed child autopsies that resulted in wrongful convictions.
The Armed Forces Institute of Pathology is a main institution for defensive research into countermeasures against biological warfare. It is located in the vicinity of CMH Rawalpindi alongside the Armed Forces Institute of Cardiology in Rawalpindi Cantt, Punjab, Pakistan. Established in 1957, the AFIP, supported by civilian and military pathologists, has been engaged in the task of combating virus outbreaks in Pakistan.
Yehuda Hiss is a retired Israeli pathologist. He served as the Chief Pathologist at the Abu Kabir Institute of Forensic Medicine between 1988 and possibly as late as 2005. Hiss has also served as part of the faculty for the Terrorism and Medicine Program at the Institute for Counter-Terrorism (ICT) at IDC Herzliya and in the Department of Pathology for the Sackler Faculty of Medicine at Tel Aviv University.
In many legal jurisdictions, the manner of death is a determination, typically made by the coroner, medical examiner, police, or similar officials, and recorded as a vital statistic. Within the United States and the United Kingdom, a distinction is made between the cause of death, which is a specific disease or injury, versus manner of death, which is primarily a legal determination versus the mechanism of death which does not explain why the person died or the underlying cause of death and can include cardiac arrest or exsanguination. Different categories are used in different jurisdictions, but manner of death determinations include everything from very broad categories like "natural" and "homicide" to specific manners like "traffic accident" or "gunshot wound". In some cases an autopsy is performed, either due to general legal requirements, because the medical cause of death is uncertain, upon the request of family members or guardians, or because the circumstances of death were suspicious.
The prosecution of Rodricus Crawford in Caddo Parish, Louisiana in 2013, attracted national media attention. Crawford, a black man, was convicted and sentenced to death that year for suffocating his one-year-old son. His death sentence was seen as part of a pattern in the parish, which has the highest rate of death penalty sentencing in the nation. The prosecutor in this case said this penalty was needed for society's revenge.
Miguel A. Sanchez is a board-certified pathologist who specializes in anatomic pathology, clinical pathology and cytopathology. Sanchez is chief of pathology and medical director of The Leslie Simon Breast Care and Cytodiagnosis Center at Englewood Hospital and Medical Center in Englewood, New Jersey. He is best known for his contribution in setting the standards of diagnosis and treatment of breast and thyroid disease praised by the United States Congress in 1994.
John Lewis Emery was a British-born paediatric pathologist and emeritus professor at the University of Sheffield. Emery was most notable for being one of the founding fathers of paediatric pathology in the country, and for conducting research into haematology, developmental anatomy, congenital deformities, particularly hydrocephalus, and was probably Britain's leading scientist in the subject of unexplained infant deaths, or cot death.
Judy Melinek is an American forensic pathologist and writer. She is a pathologist at the Wellington District Health Board and Chief Executive Officer of PathologyExpert Inc.
Javed Iqbal Kazi (1955–2014) was a Pakistani pathologist specialized in renal pathology, professor and chairman of Histopathology at Karachi Medical and Dental College, Sindh Institute of Urology & Transplantation, Dr. Ziauddin Hospitals & National Institute of Blood Diseases, and served as Dean of medicine of University of Karachi. He was also the board member of Journal of Pakistan Medical Association since 2005. He established the department of Histopathology at Sindh Institute of Urology & Transplantation, Karachi, in 1995 and is the pioneer of Renal and Transplant Pathology in Pakistan.
Marta C. Cohen OBE is a clinical pediatric pathologist, and currently head of the Department of Histopathology and Clinical Director of Pharmacy, Pathology, and Genetics at Sheffield Children's Hospital, and an honorary professor at the University of Sheffield. Her clinical work focusses on sudden infant death.
