Table of volume of distribution for drugs

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This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.

MedicationVd L/kg body weight
heparin 0.05-0.1 [1]
insulin 0.05-0.1 [1]
warfarin 0.1-0.2 [1]
sulfamethoxazole 0.1-0.2 [1]
glibenclamide 0.1-0.2 [1]
atenolol 0.1-0.2 [1]
NXY-059 0.1-0.2 [2]
tubocurarine 0.2-0.4 [1]
theophylline 0.4-0.7 [1]
ethanol 0.7-0.9 [1]
neostigmine 0.7-0.9 [1]
phenytoin 0.7-0.9 [1]
methotrexate 1-2 [1]
indometacin 1-2 [1]
paracetamol 1-2 [1]
diazepam 1-2 [1]
lidocaine 1-2 [1]
glyceryl trinitrate 2-5 [1]
morphine 2-5 [1]
propranolol 2-5 [1]
digoxin 2-5 [1]
chlorpromazine 2-5 [1]
nortriptyline 2-5 [1]
chloroquine 200 [2]

References & footnotes

  1. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN   0-443-07145-4. Page 103
  2. 1 2 Estimated with a body weight of 70 kg.

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